A methodology to assess non-axial loading on the distal radius

39e Congrès de la Société de Biomécanique, VALENCIENNES, FRANCE, 27-/08/2014 - 29/08/2014Osteoporosis is a worldwide health problem related to bone fragility. Micro-finite element analysis (mFEA) based on high-resolution peripheral quantitative computed tomography (HR-pQCT, Scanco) images are used to evaluate in vivo biomechanical properties (Boutroy et al. 2008). Most of the previous studies used an axial loading to assess the bone strength. However, among fractures due to a fall from the standing height, only 15% are related to an axial loading (Melton et al. 2010). We assumed that a non-axial loading might be more discriminant to assess bone fracture. The main aim of our study is to develop a method to compare forearm strength using axial and nonaxial loadings. To reach this goal, first step consists in developing a methodology to build a micro-finite element model allowing non-axial loadings and comparing the results along with the standard HR-pQCT mFEA axial loading.Osteoporosis is a worldwide health problem related to bone fragility. Micro-finite element analysis (mFEA) based on high-resolution peripheral quantitative computed tomography (HR-pQCT, Scanco) images are used to evaluate in vivo biomechanical properties (Boutroy et al. 2008). Most of the previous studies used an axial loading to assess the bone strength. However, among fractures due to a fall from the standing height, only 15% are related to an axial loading (Melton et al. 2010). We assumed that a non-axial loading might be more discriminant to assess bone fracture. The main aim of our study is to develop a method to compare forearm strength using axial and nonaxial loadings. To reach this goal, first step consists in developing a methodology to build a micro-finite element model allowing non-axial loadings and comparing the results along with the standard HR-pQCT mFEA axial loading

Longitudinal Bone Mineralization Assessment in Children Treated With Long-Term Parenteral Nutrition for Severe Intestinal Failure

International audienc

Distal phalangeal bone erosions observed by HR-pQCT in patients with psoriatic onycholysis

Objectives: PsA prevalence among skin psoriasis is ∼30%. Nail psoriasis, especially onycholysis, is present in >70% of PsA and the risk of developing PsA is more than doubled in patients with nail involvement. We hypothesized that onycholysis may be associated with early bone erosions of the DIP joint without harbouring PsA symptoms. Methods: We compared tendon thickness, assessed by US, and bone erosions, assessed by high-resolution peripheral quantitative CT, of the DIP joint in patients with psoriatic onycholysis without PsA (ONY) with those in patients with cutaneous psoriasis only (PSO). We used patients with PsA as reference (PsA group), and healthy age-matched controls (CTRL). Differences between groups were assessed by analysis of variance tests followed by post hoc analysis using the Scheffe method. Results: Mean (s.e.m.) age of the 87 participants (61% males) was 45.2 (1.3) years. The mean extensor tendon thickness was significantly larger in ONY than in PSO patients. In the PsA group, 68% of patients exhibited erosions of three different shapes: V-, Omega- A nd U-shape. Association with erosions was greater in the ONY group than in the PSO group (frequency: 57 vs 14%; P < 0.001; mean number of erosions: 1.10 (0.35) vs 0.03 (0.03); P < 0.001). Conclusion: Onycholysis was associated with significant enthesopathy and bone erosions in our cohort. These data support the pathogenic role of enthesopathy in PsA. Onycholysis may be considered as a surrogate marker of severity in psoriasis.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Anthropologie des abris de loisirs

Tentes, caravanes, mobil homes, cabanes, cabanons, kiosques, chalets, cabines… les abris convertis ou créés à des fins ludiques sont une réalité bien ancrée dans nos vies. À un tel point que ces objets d'une architecture pensée comme temporaire, provisoire, voire précaire, dépassent les frontières de la culture occidentale et traversent les âges. D'un point de vue anthropologique, l'abri de loisirs dévoile un habitus manuel inscrit au plus profond de nous. Il est bricolé, jardiné, techniquement agi et agissant. Sur le plan historique, ces objets divers rejouent le passage du nécessaire à l'accessoire, du sérieux au futile, dans une société des loisirs où la chasse, la pêche, la cueillette et plus largement toute une gamme d'exercices physiques sont devenus secondaires. Depuis la fin du xviiie siècle, ils n'ont cessé de se multiplier dans un ensemble de dispositifs pensés pour contrôler les masses, mais aussi dans des contextes de ruse avec les logiques de l'habitat. Cet héritage déjà long rejoue aujourd'hui les manières de penser la société. Les abris s'adressent à différents âges de la vie, ils semblent avoir un sexe et se métamorphoser selon la condition sociale de son occupant. Dans cette rencontre entre formes d'habitats et loisirs se dessinent de multiples prises sur le monde, croisant destins individuels et collectifs, rejouant la fragile réversibilité de la nature et de la culture