Projecte de condicionament del camí rural de l’Aiguabarreig al terme municipal de Massalcoreig (Lleida)

El tema d’aquest projecte és el condicionament del camí rural, situat al llarg del riu Cinca, al terme municipal de Massalcoreig (Lleida). Aquest projecte està format per quatre documents, classificats en dos volums. Al primer volum trobem el document número 1, format per la memòria amb els seus annexes on es defineixen les característiques bàsiques a tenir en compte per a realitzar el condicionament del camí, així com el desenvolupament de les activitats. Al segon volum, trobem la resta de documents. En primer lloc, trobem el segon document, els plànols necessaris per a dur a terme l’obra. A continuació, el tercer document és el plec de condicions en el que s’estipulen les normes que s’han de tenir en compte durant l’execució del projecte. Finalment, el quart document, és el pressupost, on hi ha el cost de l’obra

Microperimetry biofeedback training in a patient with bilateral myopic macular degeneration with central scotoma

Microperimetry-1 (MP-1) evaluation and MP-1 biofeedback training were done in a case of bilateral myopic macular degeneration with a central scotoma. Fixation behavior, location and stability of preferred retinal locus, eye movement speed, and mean sensitivity were assessed. The mean retinal sensitivities before, after and at 1-year after training in the right eye were 2.9 dB, 2.9 dB and 3.7 dB and in the left eye were 3.5 dB, 3.7 dB and 1.8 dB. The fixation point in the 2° gravitation circle, improved from 40% to 50% in the right eye and from 43% to 67% in the left eye. The average eye speed before, after and at 1-year after training in right eye were 0.19°/s, 0.26°/s and 0.25°/s and in left eye were 0.36°/s, 0.25°/s and 0.27°/s. Thus, biofeedback training using MP-1 can improve the visual function in patients with macular diseases and central scotoma

Mapping the human parafoveal vascular network to understand flow variability in capillaries.

Capillary flow is known to be non-homogenous between vessels and variable over time, for reasons that are poorly understood. The local properties of individual vessels have been shown to have limited explanatory power in this regard. This exploratory study investigates the association of network-level properties such as vessel depth, branch order, and distance from the feeding arteriole with capillary flow. Detailed network connectivity analysis was undertaken in 3 healthy young subjects using flood-illuminated adaptive optics retinal imaging, with axial depth of vessels determined via optical coherence tomography angiography. Forty-one out of 70 vessels studied were of terminal capillary type, i.e. fed from an arterial junction and drained by a venous junction. Approximately half of vessel junctions were amenable to fitting with a model of relative branch diameters, with only a few adhering to Murray's Law. A key parameter of the model (the junction exponent) was found to be inversely related to the average velocity (r = -0.59, p = 0.015) and trough velocity (r = -0.67, p = 0.004) in downstream vessels. Aspects of cellular flow, such as the minimum velocity, were also moderately correlated (r = 0.46, p = 0.009) with distance to the upstream feeding arteriole. Overall, this study shows that capillary network topology contributes significantly to the flow variability in retinal capillaries in human eyes. Understanding the heterogeneity in capillary flow is an important first step before pathological flow states can be properly understood. These results show that flow within capillary vessels is not affected by vessel depths but significantly influenced by the upstream feeder distance as well as the downstream vessel junction exponents, but there remains much to be uncovered regarding healthy capillary flow

Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months

Purpose: To study the long-term safety profile and visual outcomes of primary intraocular lens (IOL) implantation in infants <6 months of age. Methods: This was a retrospective observational study conducted at a tertiary eye care center in South India. Infants under 6 months meeting the selection criteria who underwent cataract surgery (lens aspiration, primary posterior capsulorhexis, and anterior vitrectomy) with primary IOL implantation between January 2008 and December 2011 and minimum 3-year follow-up were included. Patient demographics, serial refractions, visual acuity, complications, and associated amblyopia/strabismus were reviewed. Visual acuity, myopic shift, and complications were the outcome measures. Results: Sixty-nine eyes of 38 infants (31 bilateral; mean age: 4.6 months) were reviewed. Mean follow-up was 51 months (range: 36–84). Median logMAR best-corrected visual acuity at the final visit was 0.74 (interquartile range [IQR]: 0.50–0.98) in eyes with bilateral cataracts and 0.87 (IQR: 0.60–1.14) in eyes with unilateral cataracts with an average myopic shift of 6.7 diopters over 4.2 years. Most common postoperative complication was visual axis opacification (VAO) (13 eyes, 18%), necessitating membranectomy followed by pigmentary IOL deposits (11 eyes, 15%), and IOL decentration and glaucoma in four eyes each (5.6%). Mixed linear effect model found no significant association of age, gender, laterality, and postoperative complications with final visual acuity (P ≥ 0.05). Eyes with unilateral cataracts had a greater myopic shift than bilateral cases (P = 0.03). Conclusion: Primary IOL implantation in infants <6 months is reasonably safe in appropriately selected infants. VAO was the most common postoperative complication, and a large myopic shift was observed

Distribution of vessel depths from all vessels segments analysed.

The histogram plot reveals that vessel depths show a bimodal distribution with 2 peaks (indicated by red stars), 1st peak (with a frequency of about n = 14) noted at the deeper layer (at 150 μm away from PR1 layer) and the other peak (a frequency close to 7) at the superficial layer (i.e., at 200 μm away from PR1 layer). The bimodal distribution of vessel depths was also found in a given field (as given in Fig 3).</p

Illustrating the distribution of network variables and their correlations with the raw flow parameters.

Illustrating the distribution of network variables and their correlations with the raw flow parameters.</p

Vessel identifiers used to map network connections.

A: Showing motion contrast image of a supero-temporal field from subject 1. Showing the relationship of VOI with the upstream (parent) vessels and the downstream (daughter) vessels. The radii of these vessels were used to calculate the Junction exponents. Arrows indicate flow direction. Vessels of interest indicated by yellow star, parent vessel in red star, and daughter vessels represented by blue star. B: The numbers and the color code indicate unique ID for each vessel segment (reference to the DIV image in A) separated by a branch (indicated by white arrows) or a junction/crossing.</p

Establishing vessel connections.

AO montage overlaid on and registered with OCTA data for Subject 1, arrows indicate blood flow direction, arrows in cyan and yellow indicate vessels of interest, cyan represent deeper vessels, yellow represent superficial vessels, magenta indicates unknown depth & non-VOI, yellow asterisks represent feeding arterioles.</p

OCTA extraction for vessel depth analysis.

A: Enface image of the OCTA data showing perfused vessels of the chosen slab thickness. Crosshairs are positioned at a vessel segment of interest located 1.25° superior to FAZ (green line represents transverse scan and blue is the orthogonal scan). B: A close up view of Structural OCT section images with overlay of OCTA data in yellow, showing thickness slab (in red dashed lines pointed by blue arrow) positioned 160 microns away from photoreceptor layer 1 (indicated by orange arrow).</p