FABRICATION OF SODIUM ALGINATE/GUM GHATTI IPN MICROBEADS INTERCALATED WITH KAOLIN NANO CLAY FOR CONTROLLED RELEASE OF CURCUMIN

Objective: The objective of this study is to fabricate sodium alginate (SA)/gum ghatti (GG) microbeads intercalated with Kaolin (KA) nano clay for the sustained release of curcumin (CUR). Methods: The microbeads were prepared by a simple ionotropic gelation technique. The developed beads were characterized by fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), X-ray diffraction (X-RD), and scanning electron microscopy (SEM). Swelling studies and in vitro release studies were investigated under both pH 7.4 and pH 1.2 at 37 °C. Results: The developed microbeads were characterized by FTIR, which confirms the interaction between CUR, polymeric matrix and KA. DSC and XRD analysis reveals that the CUR has molecularly dispersed in the polymer matrix. In vitro results illustrated that microbeads were influenced by the pH of test media, which might be suitable for intestinal drug delivery. The drug release mechanism was analyzed by fitting the release data into different kinetic equations and n values are obtained in the range of 0.609-0.640, suggesting that the developed microbeads showed the non-Fickian diffusion type drug release. Conclusion: These results clearly illustrated that the developed KA intercalated polymeric microbeads are potential drug carriers for the controlled release of CUR

Study of Electrical and Thermal Behaviour of Li-ion Polymer Cells for Auxiliary Power Supply in Underwater Applications

Lithium  ion  polymer (Li-Po) battery technology is the latest technology for portable use and the most promising technology for exercise torpedoes. These batteries are technologically evolved from Lithium ion batteries. In this paper, extensive experimental studies on Li-Po cells which include studies on electrical characteristics during charge-discharge cycles, discharge at different C rates, self discharge throughout  charge stand, temperature profiles at the cathode and anode during the discharges, etc. are reported and discussed. The extensive electrical characterisation done on these cells indicates the capability of these cells for use as auxiliary power supply in underwater weapon applications.Defence Science Journal, 2012, 62(2), pp.127-131, DOI:http://dx.doi.org/10.14429/dsj.62.99

An Improvised Methodology to Unbar Android Mobile Phone for Forensic Examination

At the end of 2015, there were 4.7 billion noteworthy mobile subscribers globally, equivalent to 63% of the world’s population. Mobile phones had all the essential components or characteristics neatly fitted into a small space and designed to achieve high speeds, massive storage, and increased functionalities. Smart phones used to carry out imparting or exchanging of information such as calling, texting, Internet browsing, e-mail, photos, videos, and etc. Criminals can use smart phones for a number of activities. Namely, committing a fraud over e-mail, harassment via text messages, drug trafficking, child pornography, etc. In this research paper, We demonstrate, if a mobile phone is identified in a criminal activity and if it is locked by any one of the locking mechanisms such as pattern lock, PIN lock and password lock, then how to unlock the mobile device without data loss for forensic examination. It is a great challenge for forensic experts to extract data from a mobile phone for forensic purpose that can be used as evidence in the court of law. The experimental results show that our approach can break all kinds of pattern locks

Objective structured practical examination as a formative assessment tool for IInd MBBS microbiology students

Background: Assessment drives learning. It is well known that conventional or Traditional Practical Examination (TPE) has several limitations, especially in terms of subjectivity. In OSPE the procedures are standardized, so objectivity is ensured and also reliability maximized. Objectives of the study were to compare TPE & OSPE examination in formative assessment for IInd MBBS microbiology students on the topic culture media and to obtain feedback from students attending OSPE, and faculty.Methods: 76 students were taught about culture media and simultaneously were sensitized about OSPE and TPE, which followed the next week. Informed consent was taken. All students were randomly divided into 2 batches (TPE and OSPE) based on roll call. 71 students were tested, 33 for OSPE and 38 for TPE. Eight OSPE stations were set up with 8 culture media, plus a rest station after station 4. TPE students went for viva-voce to one examiner for same eight culture media. Both OSPE and TPE students were evaluated for a score of 20. OSPE students and the faculty were given a pre-validated questionnaire for feedback.Results: Mean scores, standard deviation (SD) and “p” values were calculated using the T-test from the scores obtained. The mean scores for OSPE and TPE were found to be statistically significant- p-value <0.01. Feedback from OSPE students & faculty was also evaluated.Conclusions: OSPE is more structured and eliminates examiner bias better, and should be practiced in formative assessments and also be introduced in summative assessments

Analysis of Legacy System in Software Application Development: A Comparative Survey

Software evolution is one of the challenging issues in today’s business environment. It is necessary for the organizations, which make use of Information, and Communication Technologies will have to align their business processes to compete with global business. The existing large software systems (“legacy” systems) have never been built to cope with the current business requirement for their poor coding, design structures, logic and documentation. Moreover, Legacy applications have various problems such as lack of up to-date documentation, skilled man power, resources of the Legacy applications, and high maintenance costs. Even though the Legacy system is obsolete, it contains detailed business rules and in continuous use, because it satisfies the users' needs and forms the backbone of the information flow of organization. One of the possible solutions is to refactor or modernize those systems into a new platform. It is necessary to analyse the existing legacy system for better understanding the business logic and its functionalities. This paper analyses various techniques proposed for understanding Legacy systems in existence

A New Multilevel Inverter Topology For High Step Up DC-DC Converter

High step up proportion dc–dc converters with megawatt evaluations are of enthusiasm for wind turbine interfaces and high-voltage direct current frameworks. This paper introduces a secluded multilevel dc–dc converter in view of the standard boost converter topology yet with the typical single switches supplanted by various capacitor-cinched sub modules. The converter is worked in resounding mode with reverberation between sub module capacitors and the arm inductor. A phase-shifted switching  course of action is connected with the end goal that there is a consistent number, i.e., N, of sub modules supporting the high voltage at once. In this operation mode, the progression up proportion is reliant on the quantity of sub modules and the inductor charging proportion. The converter shows versatility without utilizing a transformer and is equipped for bidirectional power stream. This venture is reached out to next sub module for expanding working scope of the converter. The outcomes checked through MATLAB/SIMULINK condition

Preparation and characterization of non-random YBa<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>7</SUB>-Ag composite

Silver addition to the high Tc superconductor, YBa2Cu3O7 (YBCO) is known to improve its mechanical properties and critical current (Jc) characteristics. We have synthesized the superconductor-metal composite YBCO-Ag by an electroless process at room temperature (using sucrose or hydrazine hydrate in an alkaline medium). The latter method produces a non-random coating whereby each grain of YBCO is coated uniformly by silver. The intrinsic high Tc of 90 K of YBCO can be recovered by compaction of the composite and subsequent heat treatment (900&#176;C and 600&#176;C) in oxygen

A Survey on Mathematics Fuzzy Logic Model

The fundamental target of mathematics instruction is to invigorate one's instinct and logical point of view. Since the instinct is fuzzy, one can't be kept to two– esteemed logical considering. There ought to be some regular introduction to build up a one's numerical deduction in fuzzy - esteemed logical way with the goal that one might have the capacity to express their instinct regarding multi esteemed logic rather than two esteemed logic to make the mathematics system more adaptable and versatile