Evaluating the Potential of the Original Texas Land Survey for Mapping Historical Land and Vegetation Cover

© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).This paper reports on research to evaluate the potential of Original Texas Land Survey (OTLS) to generate information that can be used to quantitatively map historical vegetation cover and analyse pertinent aspects of vegetation ecology. Research was conducted in Brazos County in east-central Texas. OTLS data are easy to acquire and convert to geo-referenced autecological information. Reconstructing and mapping vegetation and land cover, conducting vegetation- and species-site analyses with to soil-ecological maps, reconstructing vegetation assemblages and forest structure can be easily accomplished. Due to the irregular surveying framework used by OTLS, mapping gradational grassland-savannah ecotone boundaries is impracticable. View Full-Tex

Spatial structure of demersal fish assemblages in South and Southeast Asia and implications for fisheries management

We provide a review of the assemblage structure of demersal fish resources in four South and Southeast Asian countries. Multivariate techniques (classification and ordination analysis) were used to analyze scientific trawl survey data from a collaborative project in the region. Analyses covered major coastal fishing areas in Bangladesh, Indonesia, Malaysia, and the Philippines. This represents the first such assessment of fish assemblages for the region using a standard analysis framework. Results indicate that spatial patterns of demersal assemblages are influenced by depth. However, other environmental factors such as salinity and substrate type also appear important. Critical fisheries management implications of the observed assemblage patterns are discussed, particularly in terms of the existing spatial management zones. Existing management zones are based on distance from shore and were found to be largely inconsistent with the assemblage patterns observed. If management is to be effective it must be structured to take into account the underlying pattern of the fish assemblages

Complex interventions to implement a diabetic retinopathy care pathway in the public health system in Kerala: the Nayanamritham study protocol

Introduction: Using a type 2 hybrid effectiveness-implementation design, we aim to pilot a diabetic retinopathy (DR) care pathway in the public health system in Kerala to understand how it can be scaled up to and sustained in the whole state. Methods and analysis: Currently, there is no systematic DR screening programme in Kerala. Our intervention is a teleophthalmology pathway for people with diabetes in the non-communicable disease registers in 16 family health centres. The planned implementation strategy of the pathway will be developed based on the discrete Expert Recommendations for Implementing Change taxonomy. We will use both quantitative data from a cross-sectional study and qualitative data obtained from structured interviews, surveys and group discussions with stakeholders to report the effectiveness of the DR care pathway and evaluation of the implementation strategy. We will use logistic regression models to assess crude associations DR and sight-threatening diabetic retinopathy and fractional polynomials to account for the form of continuous covariates to predict uptake of DR screening. The primary effectiveness outcome is the proportion of patients in the non-communicable disease register with diabetes screened for DR over 12 months. Other outcomes include cost-effectiveness, safety, efficiency, patient satisfaction, timeliness and equity. The outcomes of evaluation of the implementation strategies include acceptability, feasibility, adoption, appropriateness, fidelity, penetration, costs and sustainability. Addition of more family health centres during the staggered initial phase of the programme will be considered as a sign of acceptability and feasibility. In the long term, the state-wide adoption of the DR care pathway will be considered as a successful outcome of the Nayanamritham study. Ethics and dissemination: The study was approved by Indian Medical Research Council (2018-0551) dated 13 March 2019. Study findings will be disseminated through scientific publications and the report will inform adoption of the DR care pathway by Kerala state in future

Dual variables for the SU(2) lattice gauge theory at finite temperature

We study the three-dimensional SU(2) lattice gauge theory at finite temperature using an observable which is dual to the Wilson line. This observable displays a behaviour which is the reverse of that seen for the Wilson line. It is non-zero in the confined phase and becomes zero in the deconfined phase. At large distances, it's correlation function falls off exponentially in the deconfined phase and remains non-zero in the confined phase. The dual variable is non-local and has a string attached to it which creates a Z(2) interface in the system. It's correlation function measures the string tension between oppositely oriented Z(2) domains. The construction of this variable can also be made in the four-dimensional theory where it measures the surface tension between oppositely oriented Z(2) domains.Comment: 13 pages, LaTeX, 4 figures are included in the latex fil

Another Look at Some Isogeny Hardness Assumptions

The security proofs for isogeny-based undeniable signature schemes have been based primarily on the assumptions that the One-Sided Modified SSCDH problem and the One-More SSCDH problem are intractable. We challenge the validity of these assumptions, showing that both the decisional and computational variants of these problems can be solved in polynomial time. We further demonstrate an attack, applicable to two undeniable signature schemes, one of which was proposed at PQCrypto 2014. The attack allows to forge signatures in 24λ/5 steps on a classical computer. This is an improvement over the expected classical security of 2λ, where λ denotes the chosen security parameter.SCOPUS: cp.kinfo:eu-repo/semantics/publishedCryptographers Track at the RSA Conference, CT-RSA 2020; San Francisco; United States; 24 February 2020 through 28 February 2020ISBN: 978-303040185-

A regional database management system—the fisheries resource information system and tools (FiRST): Its design, utility and future directions

South and Southeast Asian countries have undertaken demersal trawl surveys to measure the fisheries potential of their waters throughout the 20th century. However, ensuring full use of, and easy access to the resulting data is a challenge in developing countries. The “Fisheries Resource Information System and Tools” (FiRST) was developed through a regional collaborative effort across eight South and Southeast Asian counties to meet these needs. FiRST is a data management system for scientific trawl survey data and includes data summary and visualization tools, an analytical routine to estimate biomass, and data import/export modules. The FiRST software has also facilitated the establishment of a regional database, ‘Trawl Base’, which contains more than 20,000 hauls or stations from scientific trawl surveys in 10 countries conducted between 1926 and 1995. The regional database is an important regional resource for coastal fisheries management complementing national fisheries catch statistics

Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21

Meta-AnalysisThis is the final version of the article. Available from the American Diabetes Association via the DOI in this record.Indians undergoing socioeconomic and lifestyle transitions will be maximally affected by epidemic of type 2 diabetes (T2D). We conducted a two-stage genome-wide association study of T2D in 12,535 Indians, a less explored but high-risk group. We identified a new type 2 diabetes-associated locus at 2q21, with the lead signal being rs6723108 (odds ratio 1.31; P = 3.32 × 10⁻⁹). Imputation analysis refined the signal to rs998451 (odds ratio 1.56; P = 6.3 × 10⁻¹²) within TMEM163 that encodes a probable vesicular transporter in nerve terminals. TMEM163 variants also showed association with decreased fasting plasma insulin and homeostatic model assessment of insulin resistance, indicating a plausible effect through impaired insulin secretion. The 2q21 region also harbors RAB3GAP1 and ACMSD; those are involved in neurologic disorders. Forty-nine of 56 previously reported signals showed consistency in direction with similar effect sizes in Indians and previous studies, and 25 of them were also associated (P < 0.05). Known loci and the newly identified 2q21 locus altogether explained 7.65% variance in the risk of T2D in Indians. Our study suggests that common susceptibility variants for T2D are largely the same across populations, but also reveals a population-specific locus and provides further insights into genetic architecture and etiology of T2D.The major funding for this work comes from Council for Scientific and Industrial Research, Government of India, in the form of the grant “Diabetes mellitus—New drug discovery R&D, molecular mechanisms, and genetic and epidemiological factors” (NWP0032-19). R.T. received a postdoctoral fellowship from the Fogarty International Center and the Eunice Kennedy Shriver National Institute of Child Health and Human Development at the National Institutes of Health (D43-HD-065249)

Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.

Indians undergoing socioeconomic and lifestyle transitions will be maximally affected by epidemic of type 2 diabetes (T2D). We conducted a two-stage genome-wide association study of T2D in 12,535 Indians, a less explored but high-risk group. We identified a new type 2 diabetes-associated locus at 2q21, with the lead signal being rs6723108 (odds ratio 1.31; P = 3.32 × 10⁻⁹). Imputation analysis refined the signal to rs998451 (odds ratio 1.56; P = 6.3 × 10⁻¹²) within TMEM163 that encodes a probable vesicular transporter in nerve terminals. TMEM163 variants also showed association with decreased fasting plasma insulin and homeostatic model assessment of insulin resistance, indicating a plausible effect through impaired insulin secretion. The 2q21 region also harbors RAB3GAP1 and ACMSD; those are involved in neurologic disorders. Forty-nine of 56 previously reported signals showed consistency in direction with similar effect sizes in Indians and previous studies, and 25 of them were also associated (P < 0.05). Known loci and the newly identified 2q21 locus altogether explained 7.65% variance in the risk of T2D in Indians. Our study suggests that common susceptibility variants for T2D are largely the same across populations, but also reveals a population-specific locus and provides further insights into genetic architecture and etiology of T2D

The Public Health Leadership and Implementation Academy for Noncommunicable Diseases.

PURPOSE AND OBJECTIVES: Low- and middle-income countries (LMICs) have a large burden of noncommunicable diseases and confront leadership capacity challenges and gaps in implementation of proven interventions. To address these issues, we designed the Public Health Leadership and Implementation Academy (PH-LEADER) for noncommunicable diseases. The objective of this program evaluation was to assess the quality and effectiveness of PH-LEADER. INTERVENTION APPROACH: PH-LEADER was directed at midcareer public health professionals, researchers, and government public health workers from LMICs who were involved in prevention and control of noncommunicable diseases. The 1-year program focused on building implementation research and leadership capacity to address noncommunicable diseases and included 3 complementary components: a 2-month online preparation period, a 2-week summer course in the United States, and a 9-month, in-country, mentored project. EVALUATION METHODS: Four trainee groups participated from 2013 through 2016. We collected demographic information on all trainees and monitored project and program outputs. Among the 2015 and 2016 trainees, we assessed program satisfaction and pre-post program changes in leadership practices and the perceived competence of trainees for performing implementation research. RESULTS: Ninety professionals (mean age 38.8 years; 57% male) from 12 countries were trained over 4 years. Of these trainees, 50% were from India and 29% from Mexico. Trainees developed 53 projects and 9 publications. Among 2015 and 2016 trainees who completed evaluation surveys (n = 46 of 55), we saw pre-post training improvements in the frequency with which they acted as role models (Cohen's d = 0.62, P <.001), inspired a shared vision (d = 0.43, P =.005), challenged current processes (d = 0.60, P <.001), enabled others to act (d = 0.51, P =.001), and encouraged others by recognizing or celebrating their contributions and accomplishments (d = 0.49, P =.002). Through short on-site evaluation forms (scale of 1-10), trainees rated summer course sessions as useful (mean, 7.5; SD = 0.2), with very good content (mean, 8.5; SD = 0.6) and delivered by very good professors (mean, 8.6; SD = 0.6), though they highlighted areas for improvement. IMPLICATIONS FOR PUBLIC HEALTH: The PH-LEADER program is a promising strategy to build implementation research and leadership capacity to address noncommunicable diseases in LMICs