1 research outputs found
<span style="font-size:12.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-GB;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-GB">Synthesis, characterisation and anthelmintic activity of 3-(4-acetyl-5-phenyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)- 2<i style="mso-bidi-font-style: normal">H</i>-chromen-2-one derivatives</span>
422-427<span style="mso-ansi-language:
EN-US;mso-bidi-font-weight:bold" lang="EN-US">Convectional synthesis of several
coumarin-oxadiazole derivatives from starting compounds 2-hydroxy benzaldehyde and diethylmalonate has been accomplished.
Successful synthesis of the derivatives has been confirmed by spectral studies i.e. UV, IR, MS and 1H NMR.
All successfully synthesized compounds have been screened for in vitro anthelmintic activity by taking
adult Indian earthworms Pheretima
posthuma. Among all the derivatives 4-chloro derivatives have shown maximum
activity when compared with the standard.
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