Idealogical Clashes in Bharathi Mukherjee’s ‘WIFE’

The life of an Indian Women surrounded in Diasporic atmosphere takes numerous twists and always things may not go as expected. The protagonist in Bharathi Mukherjee’s Wife undergoes psychological stress in foreign world, where she is not amidst of her blood relations nor friends from the same culture. Before going to U.S.A, she looks up at that country as a land of freedom - a place where women enjoy liberty and equality. Having being suppressed from her childhood in the name of tradition and culture in India, she tries to fulfill all her unfulfilled desires after getting married to an engineer who works in U.S.A.She has a dream of settling in the land of opportunity and her husband has similar aspirations to settle in U.S.A, but faces financial  crises in the insecure and temporary jobs. In her disillusionment she restrains herself to watching T.V and gets rid of pregnancy viewing it as an obstacle of her freedom. Ultimately with the psychological depression she views her husband as a person who has failed and  kills him. The basic flaw in Dimple is that she  always expected freedom and happiness. She wanted to be loved by others but she does not love herself and the person who does not love oneself can never love anyone. Dimple lacks the self-efficiency and self actualization which comes from within oneself . The present paper focuses on her Illusion and Disillusion due to East – West Encounter

One-pot three-component synthesis of 4-aryl-3,4-dihydro-pyrimidin-2(1H)-thiones catalyzed by Ni loaded SiO2

A simple and efficient method has been developed for the synthesis of 4-aryl-3,4-dihydropyrimidin-2(1H)-thiones from methyl 3-oxopentanoate, aldehydes and thiourea in the presence of a catalytic amount of Ni loaded SiO2 at room temperature.KEY WORDS: Ni loaded SiO2, 4-Aryl-3,4-dihydropyrimidin-2(1H)-thiones, One-pot three-component synthesis, Methyl 3-oxopentanoate, Aldehydes,  Thiourea Bull. Chem. Soc. Ethiop. 2012, 26(1), 121-126.DOI: http://dx.doi.org/10.4314/bcse.v26i1.1

PHYTOPHARMACOLOGICAL REVIEW OF KNEMA ATTENUATA (HOOK F. AND THOMSON) WARB

Knema attenuata, a member of Myristicaceae family and commonly known to world as ‘wild nutmeg’ is broadly used in folk medicine for treating ailments such as jaundice, chronic fever, inflammations, spleen disorders, breathing disorders and impaired taste sensation. This review article aims to compile all the updated information on the phytochemical and pharmacological activities of plant Knema attenuata. Studies indicate that different parts such as aril, seed and stem bark of the plant is rich in phenolics, flavonoids, tannins, steroids, terpenes, resins and glycolipids. Moreover, stem bark of Knema attenuata contains a lignan ‘attenuol’ with diverse pharmacological activities. In addition, different extracts of plant parts have been found to possess various pharmacological activities such as antioxidant, antifungal, larvicidal, analgesic, anti-inflammatory, antihyperlipidemic, and hepatoprotective activities. More research on phytochemical composition and therapeutic implications are recommended

A splendid method for synthesis of 2-(benzothiazole)-3-phenyl acrylonitrile derivatives catalysed by piperdine

A simple and efficient method is developed for the synthesis of 2-(benzothiazol-2-yl)-3-(substituted phenyl)acrylonitrile from 2-(benzothiazole-2-yl)-3-oxopentanedinitrile and aromatic aldehydes in the presence of a catalytic amount of piperdine into ethanol at reflux. Advantage of this procedure is relatively good yields (81-86%) with short reaction times (1.5-3 h), under moderate reaction conditions and simple workup procedure, plus easy preparation and handling of the catalyst.DOI: http://dx.doi.org/10.4314/bcse.v26i3.1

Bulk viscosity in hyperonic star and r-mode instability

We consider a rotating neutron star with the presence of hyperons in its core, using an equation of state in an effective chiral model within the relativistic mean field approximation. We calculate the hyperonic bulk viscosity coefficient due to nonleptonic weak interactions. By estimating the damping timescales of the dissipative processes, we investigate its role in the suppression of gravitationally driven instabilities in the $r$-mode. We observe that $r$-mode instability remains very much significant for hyperon core temperature of around $10^8$K, resulting in a comparatively larger instability window. We find that such instability can reduce the angular velocity of the rapidly rotating star considerably upto $\sim0.04 \Omega_K$, with $\Omega_K$ as the Keplerian angular velocity.Comment: 10 pages including 7 figure

On attributes of a Rotating Neutron star with a Hyperon core

We study the effect of rotation on global properties of neutron star with a hyperon core in an effective chiral model with varying nucleon effective mass within a mean field approach. The resulting gross properties of the rotating compact star sequences are then compared and analyzed with other theoretical predictions and observations from neutron stars. The maximum mass of the compact star predicted by the model lies in the range $(1.4-2.4) ~M_{\odot}$ at Kepler frequency $\Omega_K$, which is consistant with recent observation of high mass stars thereby reflecting the sensitivity of the underlying nucleon effective mass in the dense matter EoS. We also discuss the implications of the experimental constraints from the flow data from heavy-ion collisions on the global properties of the rotating neutron stars.Comment: 11 Pages, 10 Figures and 2 Table

Development of Extended Release Formulations of Ilaprazole Tablets

Extended release products are designed to release their medication in a controlled manner at a predetermined rate, duration, and location to achieve and maintain optimum therapeutic blood levels of a drug. The objective of the study is to formulate and evaluate Ilaprazole Controlled release tablets comparable to the innovator product. F1-F9 formulations were prepared using varying concentrations of super disintegrates like Crospovidone, Croscarmellose sodium and Sodium starch glycolate in different concentrations. Based on the hardness, friability, weight variation, drug content, F6 formulation was found to be optimised. The selected F6 formulation was sub coated with HPMC P 50 and followed by enteric coating with Acryl-EZE-80 (Eudragit L100-55). 3 formulations (F10-F12) were prepared by using coating. Among the three formulations, F11 formulation was found to be best. FTIR studies were carried out to find out drug and excipient compatibility studies, the studies revealed that there were no interactions. DSC studies also carried out to demonstrate any changes in physical forms of the drug molecule. Keywords: Ilaprazole, Extended release tablets, Crospovidone, Croscarmellose sodium, Sodium starch glycolate, HPMC P 50, Acryl-EZE-80