Additional file 3: of Age-driven modulation of tRNA-derived fragments in Drosophila and their potential targets

Significantly enriched GO terms in the analysis of potential targets of mt:SerGCT. AmiGO [32] output (showing enrichment of specific GO terms) is provided for the three GO catgories in three respective worksheets. (XLSX 16 kb

Additional file 1: of Age-driven modulation of tRNA-derived fragments in Drosophila and their potential targets

Significantly enriched GO terms in the analysis of potential targets of GlyGCC. AmiGO [32] output (showing enrichment of specific GO terms) is provided for the three GO catgories in three respective worksheets. (XLSX 8 kb

Supplementary Figure S6 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression

Supplementary Figure S6. Graphical abstract depicting the pro-metastatic role and mechanism of Trp53R172H-dependent Csf-1/Csf-1r signaling.</p

Supplementary Table S1 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression

Supplementary Table S1. List of oligonucleotides used in the study.</p

Supplementary Figure S5 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression

Supplementary Figure S5. CSF-1/CSF-1R signaling associates positively with clinical outcomes, and leukocyte infiltration ESCC.</p

Supplementary Table S2 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression

Supplementary Table S2. List of antibodies and dilutions used in the study.</p

Supplementary Figure S4 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression

Supplementary Figure S4. Depletion of Brd4 reduces Csf1 secretion and ESCC tumor cell invasion.</p

Supplementary Figure S2 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression

Supplementary Figure S2. Trp53R172H-dependent Csf-1/Csf-1r signaling promotes metastasis only in the presence of p53-R172H, but not p53 null or wild-type p53.</p

Supplementary Table S3 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression

Supplementary Table S3. Statistics of aligned reads from the CUT&RUN-seq analysis of H3K27ac in ESCC cells with Trp53R172H/- (n=3) and Trp53+/+ (n=2).</p