Economic Development: Diagnosis of the High Andean Valleys of Venezuela (Tuname and Burbusay)

The primary objective of this study was to set development policies applicable for the high Andean valleys of Tuname and Burbusay (Venezuela) ; and secondly to develop a quick and inexpensive way to assess development prospects of high Andean valleys similar to the ones studied here. The methodology employed was to classify various agricultural regions with specific development phases using the Thorbecke\u27s classification and policy scheme. Production functions were estimated, fitted and analyzed to determine the parameters pertinent to such a classification for the two valleys where data was available. The analyses and classifications permitted a limited enumeration of policies for the valleys that could logically be expected to bring economic development. However, the study fell short of devising a quick and inexpensive method to assess developmental prospects of similar areas, which would not require some additional data collection and further refinement of the evaluation methodology

Volcanic Water Vapour Abundance Retrieved Using Hypespectral Data

In the present study a remote sensing differential absorption technique, already developed to calculate the atmospheric water vapour abundance, has been adapted to calculate water vapour columnar abundance in tropospheric volcanic plume. Water vapour is the most abundant gas of a volcanic plume released into the atmosphere from an active volcanic system. The technique is based on the correlation between the dip in the spectral curve measured by the spectrometer were water vapour absorptions bands are presents, and the precipitable water content in the column. Airborne and satellite remote sensing images in the infrared wavelength range were used. The technique has been applied to data acquired over two different degassing volcanoes. The Airborne Visible and Infrared Imaging Spectrometer (AVIRIS) acquired data over the Hawaiian Pu’u’O’o Vent cone of the Kilauea volcano on April 2000. The Hyperion sensor on EO-1 satellite has been requested to acquire data on July 2003, during a ground-based measurements campaign on Mt. Etna (Italy). The result is the spatial distribution of water vapour abundance of the Mt. Etna and of the Pu`u` O`o Vent volcanic plumes. A comparison between the two results has been done, showing the differences in the volcanic activity. The algorithm produces reliable results compared to the ground based measurements in the plume area acquired during a measurements campaign over Mt. Etna

The Role of Kynurenines Produced by Indolamine-2,3-Dioxygenase 1 in Sepsis.

BACKGROUND The enzyme indolamine-2,3-dioxygenase 1 (IDO1) is the rate-limiting enzyme of the kynurenine (KYN) pathway and metabolizes the essential amino acid tryptophan to KYNs. The depletion of tryptophan and the generation of KYNs were shown to be involved in the global downregulation of the immune system during the later stages of sepsis, also referred to as sepsis-associated immunosuppression. SUMMARY The generation of KYNs by IDO1 leads to a depletion of effector T cells, including increased rate of apoptosis, decreased ability of T-cell proliferation and activation, and the generation of FoxP3+ regulatory T cells. Furthermore, KYN was shown a potent vasorelaxant during inflammation-induced hypotension. Experimental studies in murine sepsis models and in humans show promising data for using the activation of IDO1 both as a prognostic marker and potential drug target in sepsis

Near real-time routine for volcano monitoring using infrared satellite data

An Advanced Very-High-Resolution Radiometer (AVHRR) routine for hotspot detection and effusion rate estimation (AVHotRR) using AVHRR infrared space-borne images is presented here for the monitoring of active lava flow. AVHotRR uses directly broadcast National Oceanic and Atmospheric Administration (NOAA)-AVHRR remotely sensed data. The 2006 summit eruption of Mount Etna provided the opportunity to test the products generated by AVHotRR for monitoring purposes. Low spatial and high temporal resolution products can also be used as inputs of flow models to drive numerical simulations of lava-flow paths and thus to provide quantitative hazard assessment and volcanic risk mitigation

water dynamics at the root of metamorphosis in living organisms

Liquid water has been recognized long ago to be the matrix of many processes, including life and also rock dynamics. Interactions among biomolecules occur very differently in a non-aqueous system and are unable to produce life. This ability to make living processes possible implies a very peculiar structure of liquid water. According to modern Quantum Field Theory (QFT), a complementary principle (in the sense of Niels Bohr) holds between the number N of field quanta (including the matter field whose quanta are just the atoms/molecules) and the phase Ф. This means that when we focus on the atomic structure of matter it loses its coherence properties and, vice versa, when we examine the phase dynamics of the system its atomic structure becomes undefined. Superfluid liquid Helium is the first example of this peculiar quantum dynamics. In the present paper we show how consideration of the phase dynamics of liquid water makes the understanding of its peculiar role in the onset of self-organization in living organisms and in ecosystems possible

The Bone Marrow Endosteal Niche: How Far from the Surface?

aaHematopoietic stem cells (HSC) self‐renewal takes place in the same microenvironment in which massive hematopoietic progenitor proliferation, commitment, and differentiation will occur. This is only made possible if the bone marrow microenvironment comprises different specific niches, composed by different stromal cells that work in harmony to regulate all the steps of the hematopoiesis cascade. Histological and functional assays indicated that HSC and multipotent progenitors preferentially colonize the endosteal and subendosteal regions, in close association with the bone surface. Conversely, committed progenitors and differentiated cells are distributed in the central and perisinusoidal regions, respectively. Over the last decade, many investigative teams sought to define which cell types regulate the HSC niche, how they are organized, and to what extent they interface with each other. System dynamics requires different stromal cells to operate distinct functions over similar HSC pools rather than a single stromal cell type controlling everything. Therefore, our focus herein is to depict the players in the endosteal and subendosteal regions, named the endosteal niche, a necessary step to better understand the interactions of the HSC within the niche and to identify potential targets to manipulate and/or modulate normal and malignant HSC behavior. J. Cell. Biochem. 116: 6–11, 2015. © 2014 Wiley Periodicals, Inc.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109640/1/jcb24952.pd