29 research outputs found
Texts, Bodies, and the Memory of Bloody Sunday
We examine here recent arguments that embodied experience is an
important site of collective memory, and related challenges to the
standard emphasis on discourse and symbols in collective memory
research. We argue that although theories of embodied memory offer
new insights, they are limited by (1) an overdrawn distinction between
embodied memory and textual memory that neglects the complex
relations between the two, (2) an overemphasis on ritual performance
at the expense of collective conversation, (3) an oversimplified view of
performativity, and (4) an underestimation of the ambiguity in embodied
performance. Theories of embodied collective memory should be
narrowed and specified with focused comparisons examining the
influence of embodied experience in the formation of collective identities,
in conflicts over collective memories, and in the persistence and
malleability of memories across generations. We illustrate our argument
throughout with examples drawn from the collective memory of
Bloody Sunday in Northern Ireland in 1972
The politics and aesthetics of commemoration: national days in southern Africa
The contributions to the special section in this issue study recent independence celebrations and other national days in South
Africa, Namibia, Zimbabwe, Madagascar and the Democratic Republic of Congo. They explore the role of national days in
state-making and nation-building, and examine the performativity of nationalism and the role of performances in national
festivities. Placing the case studies in a broader, comparative perspective, the introduction first discusses the role of the state in
national celebrations, highlighting three themes: firstly, the political power-play and contested politics of memory involved in
the creation of a country’s festive calendar; secondly, the relationship between state control of national days and civic or
popular participation or contestation; and thirdly, the complex relationship between regional and ethnic loyalties and national
identifications. It then turns to the role of performance and aesthetics in the making of nations in general, and in national
celebrations in particular. Finally, we look at the different formats and meanings of national days in the region and address the
question whether there is anything specific about national days in southern Africa as compared to other parts of the continent
or national celebrations world-wide.Web of Scienc
Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box
Chemical matter is needed to target the divergent biology associated with the different life cycle stages of Plasmodium. Here, we report the parallel de novo screening of the Medicines for Malaria Venture (MMV) Pandemic Response Box against Plasmodium asexual and liver stage parasites, stage IV/V gametocytes, gametes, oocysts and as endectocides. Unique chemotypes were identified with both multistage activity or stage-specific activity, including structurally diverse gametocyte-targeted compounds with potent transmission-blocking activity, such as the JmjC inhibitor ML324 and the antitubercular clinical candidate SQ109. Mechanistic investigations prove that ML324 prevents histone demethylation, resulting in aberrant gene expression and death in gametocytes. Moreover, the selection of parasites resistant to SQ109 implicates the druggable V-type H+-ATPase for the reduced sensitivity. Our data therefore provides an expansive dataset of compounds that could be redirected for antimalarial development and also point towards proteins that can be targeted in multiple parasite life cycle stages.Supplementary Data 1: Data of the supra-hexagonal plot in Figure 2ASupplementary Data 2: Complete dataset of all MMV PRB compounds’ activity on Plasmodium life cycle stagesSupplementary Data 3: Full SMFA dataset to support Figure 5CSupplementary Data 4: Transcriptome analysis of MMV1580488 (ML324) treated parasites to support Figure 6C.The Medicines for Malaria Venture and South African Technology Innovation Agency (TIA). This project was in part supported by the South African Medical Research Council with funds received from the South African Department of Science and Innovation, in partnership with the Medicines for Malaria Venture; and the DST/NRF South African Research Chairs Initiative Grant; and CSIR Parliamentary Grant funding as well as the Bill and Melinda Gates Foundation and the Australian NHMRC (APP1072217).http://www.nature.com/ncommshj2021BiochemistryGeneticsMicrobiology and Plant PathologyUP Centre for Sustainable Malaria Control (UP CSMC
Texts, Bodies, and the Memory of Bloody Sunday
We examine here recent arguments that embodied experience is an
important site of collective memory, and related challenges to the
standard emphasis on discourse and symbols in collective memory
research. We argue that although theories of embodied memory offer
new insights, they are limited by (1) an overdrawn distinction between
embodied memory and textual memory that neglects the complex
relations between the two, (2) an overemphasis on ritual performance
at the expense of collective conversation, (3) an oversimplified view of
performativity, and (4) an underestimation of the ambiguity in embodied
performance. Theories of embodied collective memory should be
narrowed and specified with focused comparisons examining the
influence of embodied experience in the formation of collective identities,
in conflicts over collective memories, and in the persistence and
malleability of memories across generations. We illustrate our argument
throughout with examples drawn from the collective memory of
Bloody Sunday in Northern Ireland in 1972
Texts, Bodies, and the Memory of Bloody Sunday
We examine here recent arguments that embodied experience is an
important site of collective memory, and related challenges to the
standard emphasis on discourse and symbols in collective memory
research. We argue that although theories of embodied memory offer
new insights, they are limited by (1) an overdrawn distinction between
embodied memory and textual memory that neglects the complex
relations between the two, (2) an overemphasis on ritual performance
at the expense of collective conversation, (3) an oversimplified view of
performativity, and (4) an underestimation of the ambiguity in embodied
performance. Theories of embodied collective memory should be
narrowed and specified with focused comparisons examining the
influence of embodied experience in the formation of collective identities,
in conflicts over collective memories, and in the persistence and
malleability of memories across generations. We illustrate our argument
throughout with examples drawn from the collective memory of
Bloody Sunday in Northern Ireland in 1972
Sociologia Culturale
La sociologia culturale mira a comprendere il ruolo che la cultura, la differenza culturale e il conflitto culturale svolgono in tutti i settori della realtà sociale. Attingendo a una ricca varietà di esempi tratti da ricerche sia classiche che contemporanee, il libro presenta un quadro analitico in cui va a inscriversi l'intero campo disciplinare. Nei capitoli centrali l'autrice introduce prospettive e approcci di volta in volta diversi, che si integrano poi per spiegare i processi di meaning-making e la funzione che essi hanno nella vita di relazione: la costruzione di significato attraverso le forme simboliche, l'interazione come processo di costruzione di significato, la produzione di cultura attraverso organizzazioni, strutture e istituzioni