352 research outputs found
Π’Π΅Ρ Π½ΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°Π½Π³Π»ΠΈΠΉΡΠΊΠΈΠΉ ΡΠ·ΡΠΊ Π΄Π»Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠΎΡΠ΅ΡΡΠΈΠΎΠ½Π°Π»ΡΠ½ΡΡ ΡΠΌΠ΅Π½ΠΈΠΉ Ρ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΡΡΠΎΠ² Π°Π²ΠΈΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠΈΠ»Ρ
Π¦Π΅Π»ΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΡΡ
ΡΠΌΠ΅Π½ΠΈΠΉ Ρ Π±ΡΠ΄ΡΡΠΈΡ
ΠΏΠΈΠ»ΠΎΡΠΎΠ² ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΡΡ
Π°Π²ΠΈΠ°Π»ΠΈΠ½ΠΈΠΉ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΠΌΠ΅ΠΆΠΏΡΠ΅Π΄ΠΌΠ΅ΡΠ½ΡΡ
ΡΠ²ΡΠ·Π΅ΠΉ ΡΠ΅Ρ
Π½ΠΈΡΠ΅ΡΠΊΠΈΡ
Π΄ΠΈΡΡΠΈΠΏΠ»ΠΈΠ½
ΠΠΎΠΊΡΠΌΠ΅Π½ΡΠ°Π»ΡΠ½Π° ΡΠΏΠ°Π΄ΡΠΈΠ½Π° Π΄ΡΡΡΡΠ² Π±ΡΠ»ΠΎΡΡΡΡΠΊΠΎΡ ΠΊΡΠ»ΡΡΡΡΠΈ Π² Π°ΡΡ ΡΠ²Π°Ρ Π£ΠΊΡΠ°ΡΠ½ΠΈ
In an earlier article, we analysed the actuality and potential of participation at the international level, or more specifically: at the level of the United Nations (un). Is there a demand for public participation in the work of the United Nations, and if so, who has such demands? And how should the un meet these demands? In this article we will apply the theory presented in the first article to a case study: global public participation in the drafting process, at the un, of the Sustainable Development Goals will be examined and assessed against the findings uncovered in the first article
Π‘ΡΡΠ°Π½Π° Π΄Π΅ΡΡΡΠ²Π° Π²ΡΠ΄Π°ΡΡΠ΅Π³ΠΎΡΡ ΡΡΠ΅Π½ΠΎΠ³ΠΎ
Π Π΅ΡΠ΅Π½Π·ΡΡ Π½Π° ΠΊΠ½ΠΈΠ³Ρ: Π‘ΠΎΠΊΠΎΠ»ΠΎΠ² Π.Π‘. ΠΠ°ΠΏΠΈΡΠΊΠΈ Ρ Π±Π΅ΡΠ΅Π³ΠΎΠ² ΠΠΌΠΎΠ»ΠΎΠΆΡΡ. β Π‘ΠΠ±.: Π Π΅ΡΠΈΡ
ΠΎΠ²ΡΠΊΠΈΠΉ ΡΠ΅Π½ΡΡ Π‘ΠΠ±ΠΠ£; ΠΡΡΠ½ΠΈΠΉ ΠΠΎΠ»ΠΎΡΡΠΊ: ΠΡΠΈΠ΄Π°-ΠΏΡΠ΅ΡΡ, 2007. β 448 Ρ. (Π‘Π΅ΡΠΈΡ Β«Π©Π΅Π΄ΡΡΠΉ Π΄Π°ΡΒ». β ΠΡΠΏ.. IV).ΠΠΊΠ°Π΄Π΅ΠΌΠΈΠΊ Π ΠΠ ΠΠΎΡΠΈΡ Π‘Π΅ΡΠ³Π΅Π΅Π²ΠΈΡ Π‘ΠΎΠΊΠΎΠ»ΠΎΠ² β ΠΊΡΡΠΏΠ½Π΅ΠΉΡΠΈΠΉ ΡΡΠ΅Π½ΡΠΉ-Π΅ΡΡΠ΅ΡΡΠ²ΠΎΠΈΡΠΏΡΡΠ°ΡΠ΅Π»Ρ, ΡΠΈΡΠΎΠΊΠΎ ΠΈΠ·Π²Π΅ΡΡΠ½ΡΠΉ Π½Π° ΠΏΠΎΡΡΡΠΎΠ²Π΅ΡΡΠΊΠΎΠΌ ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅ ΠΈ Π·Π° ΡΡΠ±Π΅ΠΆΠΎΠΌ ΡΡΡΠ΄Π°ΠΌΠΈ ΠΏΠΎ ΠΏΠ°Π»Π΅ΠΎΠ½ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈΡΠΊΠΎΠΏΠ°Π΅ΠΌΡΡ
ΠΊΠΎΡΠ°Π»Π»ΠΎΠ² ΠΈ Π΄ΡΠ΅Π²Π½Π΅ΠΉΡΠΈΠΌ Π³ΡΡΠΏΠΏΠ°ΠΌ ΠΎΡΠ³Π°Π½ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΌΠΈΡΠ°, ΠΏΠΎ ΡΡΡΠ°ΡΠΈΠ³ΡΠ°ΡΠΈΠΈ, ΠΏΠ°Π»Π΅ΠΎΠ³Π΅ΠΎ Π³ΡΠ°ΡΠΈΠΈ, ΡΠ΅Π³ΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠΉ Π³Π΅ΠΎΠ»ΠΎΠ³ΠΈΠΈ, Π³Π΅ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π½Π΅ΡΡΠΈ ΠΈ Π³Π°Π·Π° Π ΡΡΡΠΊΠΎΠΉ ΠΏΠ»Π°ΡΡΠΎΡΠΌΡ, Π‘ΠΈΠ±ΠΈΡΠΈ, Π‘ΡΠ΅Π΄Π½Π΅ΠΉ ΠΠ·ΠΈΠΈ ΠΈ ΠΠΈΡΠ°Ρ, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ ΡΡΠ΅Π½ΠΈΡ Π.Π. ΠΠ΅ΡΠ½Π°Π΄ΡΠΊΠΎΠ³ΠΎ ΠΎ Π±ΠΈΠΎΡΡΠ΅ΡΠ΅. Π.Π‘. Π‘ΠΎΠΊΠΎΠ»ΠΎΠ² β Π»Π°ΡΡΠ΅Π°Ρ ΠΠ΅Π½ΠΈΠ½ΡΠΊΠΎΠΉ ΠΏΡΠ΅ΠΌΠΈΠΈ (1967), ΠΠ΅ΡΠΎΠΉ Π‘ΠΎΡΠΈΠ°Π»ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π’ΡΡΠ΄Π° (1984), Π»Π°ΡΡΠ΅Π°Ρ ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΠΎΠΉ ΠΏΡΠ΅ΠΌΠΈΠΈ ΠΈΠΌΠ΅Π½ΠΈ ΠΠ°ΡΠΏΠΈΠ½ΡΠΊΠΎΠ³ΠΎ β Π¨Π²Π΅ΠΉΡΠ΅ΡΠ°, ΡΠΎΡΡΠΈΠΉΡΠΊΠΎΠΉ Π½Π΅Π·Π°Π²ΠΈΡΠΈΠΌΠΎΠΉ ΠΏΡΠ΅ΠΌΠΈΠΈ Β«Π’ΡΠΈΡΠΌΡΒ» ΠΈ ΠΌΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΠΎΠΉ ΠΏΡΠ΅ΠΌΠΈΠΈ ΠΈΠΌΠ΅Π½ΠΈ ΠΠΈΠΊΠΎΠ»Π°Ρ Π Π΅ΡΠΈΡ
Π°, ΡΡΠΈ Π΄Π΅ΡΡΡΠΊΠ° Π»Π΅Ρ ΠΎΠ½ Π²ΠΎΠ·Π³Π»Π°Π²Π»ΡΠ» Π² Π‘Π‘Π‘Π ΠΈ Π ΠΎΡΡΠΈΠΈ Π°Π²ΡΠΎΡΠΈΡΠ΅ΡΠ½Π΅ΠΉΡΠ΅Π΅ Π½Π°ΡΡΠ½ΠΎΠ΅ ΠΎΠ±ΡΠ΅ΡΡΠ²ΠΎ β ΠΠ°Π»Π΅ΠΎΠ½ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅, Ρ 1980 Π³. β ΠΏΡΠ΅Π·ΠΈΠ΄Π΅Π½Ρ ΠΠ΅ΠΆΠ΄ΡΠ½Π°ΡΠΎΠ΄Π½ΠΎΠΉ ΠΏΠ°Π»Π΅ΠΎΠ½ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π°ΡΡΠΎΡΠΈΠ°ΡΠΈΠΈ
Editorial for Localising the Sustainable Human Right to Water
This Special Issue on Localising the Sustainable Human Right to Water begins with contributions focused on a global and more general perspective. These contributions provide a general introduction to the topic of the sustainable human right to water.
It then shifts perspective to provide regional contributions, and finally zooms in to contributions focused on the implementation of this right at the national level
Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide
Background
Hypertension is, amongst others, characterized by endothelial dysfunction and vascular remodeling. As sphingolipids have been implicated in both the regulation of vascular contractility and growth, we investigated whether sphingolipid biology is altered in hypertension and whether this is reflected in altered vascular function. Methods and Findings
In isolated carotid arteries from spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats, shifting the ceramide/S1P ratio towards ceramide dominance by administration of a sphingosine kinase inhibitor (dimethylsphingosine) or exogenous application of sphingomyelinase, induced marked endothelium-dependent contractions in SHR vessels (DMS: 1.4Β±0.4 and SMase: 2.1Β±0.1 mN/mm; n = 10), that were virtually absent in WKY vessels (DMS: 0.0Β±0.0 and SMase: 0.6Β±0.1 mN/mm; n = 9, p Conclusions
Hypertension is associated with marked alterations in vascular sphingolipid biology such as elevated ceramide levels and signaling, that contribute to increased vascular tone
f0(980) production in inelastic pp collisions at s = 5.02 TeV
The measurement of the production of f0(980) in inelastic pp collisions at sqrt(s) = 5.02 TeV is presented. This is the first reported measurement of inclusive f0(980) yield at LHC energies. The production is measured at midrapidity, |y| pi+pi- hadronic decay channel using the ALICE detector. The pT-differential yields are compared to those of pions, protons and Ο mesons as well as to predictions from the HERWIG 7.2 QCD-inspired Monte Carlo event generator and calculations from a coalescence model that uses the AMPT model as an input. The ratio of the pT-integrated yield of f0(980) relative to pions is compared to measurements in e+e- and pp collisions at lower energies and predictions from statistical hadronisation models and HERWIG 7.2. A mild collision energy dependence of the f0(980) to pion production is observed in pp collisions from SPS to LHC energies. All considered models underpredict the pT-integrated 2f0(980)/(pi+ + pi-) ratio. The prediction from the canonical statistical hadronisation model assuming a zero total strangeness content of f0(980) is consistent with the data within 1.9Ο and is the closest to the data. The results provide an essential reference for future measurements of the particle yield and nuclear modification in pβPb and PbβPb collisions, which have been proposed to be instrumental to probe the elusive nature and quark composition of the f0(980) scalar meson
First measurement of Ξ©c 0 production in pp collisions at s=13 TeV
The inclusive production of the charmβstrange baryon Omega_c^0 is measured for the first time via its hadronic decay into Omega-pi+ at midrapidity (|y|<0.5) in protonβproton (pp) collisions at the centre-of-mass energy sqrt(s) = 13 TeV with the ALICE detector at the LHC. The transverse momentum (pT) differential cross section multiplied by the branching ratio is presented in the interval 2 < pT < 12 GeV/c . The pT dependence of the Omega_C^0-baryon production relative to the prompt D^0-meson and to the prompt Csi_C^0-baryon production is compared to various models that take different hadronisation mechanisms into consideration. In the measured pT interval, the ratio of the pT-integrated cross sections of Omega_c^0 and prompt Lambda_c^+ baryons multiplied by the Omega- pi+ branching ratio is found to be larger by a factor of about 20 with a significance of about 4Ο when compared to e+e- collisions
Photoproduction of low-pT J/Ο from peripheral to central PbβPb collisions at 5.02 TeV
An excess of J/Ο yield at very low transverse momentum (pT < 0.3 GeV/c), originating from coherent photoproduction, is observed in peripheral and semicentral hadronic PbβPb collisions at a center-of-mass energy per nucleon pair of sqrt(sNN) = 5.02 TeV. The measurement is performed with the ALICE detector via the dimuon decay channel at forward rapidity (2.5 < y <4). The nuclear modification factor at very low pT and the coherent photoproduction cross section are measured as a function of centrality down to the 10% most central collisions. These results extend the previous study at sqrt(sNN) = 2.76 TeV, confirming the clear excess over hadronic production in the pT range 0-0.3 GeV/c and the centrality range 70β90%, and establishing an excess with a significance greater than 5Ο also in the 50β70% and 30β50% centrality ranges. The results are compared with earlier measurements at sqrt(sNN) = 2.76 TeV and with different theoretical predictions aiming at describing how coherent photoproduction occurs in hadronic interactions with nuclear overlap
Measurement of beauty-strange meson production in PbβPb collisions at sNN=5.02TeV via non-prompt Ds + mesons
The production yields of non-prompt D_s^+ mesons, namely D_s^+ mesons from beauty-hadron decays, were measured for the first time as a function of the transverse momentum (pT) at midrapidity (|y| phi pi+, with phi -> K+ K-, in the 4 < pT < 36 GeV/c and 2 < pT < 24 GeV/c intervals for the 0β10% and 30β50% centrality classes, respectively. The measured yields of non-prompt D_S^+ mesons are compared to those of prompt D_s^+ and non-prompt D0 mesons by calculating the ratios of the production yields in PbβPb collisions and the nuclear modification factor RAA. The ratio between the RAA of non-prompt D_s^+ and prompt D_s^+ mesons, and that between the RAA of non-prompt D_s^+ and non-prompt D0 mesons in central PbβPb collisions are found to be on average higher than unity in the 4 < pT < 12 GeV/c interval with a statistical significance of about 1.6 sigma and 1.7 sigma, respectively. The measured RAA ratios are compared with the predictions of theoretical models of heavy-quark transport in a hydrodynamically expanding QGP that incorporate hadronisation via quark recombination
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