1,396 research outputs found

    Neutrons from Piezonuclear Reactions

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    We report the results obtained by cavitating water solutions of iron salts (iron chloride and iron nitrate) with different concentrations at different ultrasound powers. In all cases we detected a neutron radiation well higher than the background level. The neutron production is perfectly reproducible and can at some extent be controlled. These evidences for neutron emission generated by cavitation support some preliminary clues for the possibility of piezonuclear reactions (namely nuclear reactions induced by pressure and shock waves) obtained in the last ten years. We have been able for the first time to state some basic features of such a neutron emission induced by cavitation, namely: 1) a marked threshold behavior in power, energy and time; 2) its occurring without a concomitant production of gamma radiation.Comment: 8 figures; we added some more important references; we replaced some figures with more detailed ones; we added more comprehensive details which could not be desclosed before as part of private patents which have been published no

    Structural variants of chromosome 9: a possibile association with hypogonadotropic hypogonadism

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    We report two cases of structural variations of chromosome 9 associated with hypogonadotropic hypogonadism and azoospermia in adolescent boys. One patient also had a partially imperforated urethral meatus. Histological examination revealed that both had hypotrophic and underdeveloped testes. There was no LH and FSH response to LH-RH stimulation nor was there any response to naloxone tests. Basal and HCG stimulated plasma testosterone values were below normal prepubertal levels. As the administration of gonadotrophins did not improve the clinical and hormonal findings, alternative androgen therapy was necessary to achieve secondary sexual characteristics. Although they reached a good level of androgenization, their testes were still very small and azoospermia remained, as confirmed by repeated semen analyses. A possible association between chromosome 9 polymorphisms and hypothalamo-pituitary axis abnormalities is suggested. It is hypothesized that structural variants of chromosome 9 are not unrelated occurrences. Furthermore, and in view of the fact that they can lead to a high risk of azoospermia and infertility, such variants call for clinical investigatio

    Investigation of potential extreme load reduction for a two-bladed upwind turbine with partial pitch

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    This paper presents a wind turbine concept with an innovative design combining partial pitch with a two-bladed (PP-2B) turbine configuration. Special emphasis is on extreme load reduction during storm situations at standstill, but operational loads are also investigated. In order to compare the loads and dynamics of the PP-2B turbine, a partial pitch three-bladed (PP-3B) turbine and a normal pitch regulated three-bladed (3B) turbine are introduced on the basis of solidity similarity scaling. From the dynamic comparisons between two- and three-bladed turbines, it has been observed that the blade vibrations are transferred differently from the rotor to the tower. For a three-bladed turbine, blade vibrations seen in a fixed frame of reference are split with ±1P only. A two-bladed turbine has a similar split of ±1P but also includes contributions on higher harmonics (±2P, ±3P, ... etc.). Further on, frequency split is also seen for the tower vibrations, where an additional ±2P contribution has been observed for the two-bladed turbine. Regarding load comparisons, the PP-2B turbine produces larger tower load variations because of 2P excitation during the operational cases. However, extreme loads are reduced by approximately 20% for the PP-2B and 18% for the PP-3B compared with the 3B turbine for the parked condition in a storm situation. Moreover, a huge potential of 60% is observed for the reduction of the extreme tower bottom bending moment for the PP-2B turbine, when the wind direction is from ±90° to the turbine, but this also requires that the turbine is parked in a T-configuration

    Práticas de conservação de solos sob pastagens para Mato Grosso do Sul: revisão bibliográfica.

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    Solos de Mato Grosso do Sul. Degradação. Práticas de conservação do solo em pastagens.bitstream/item/135511/1/DOC-54.pd

    Mangosteen Extract Shows a Potent Insulin Sensitizing Effect in Obese Female Patients: A Prospective Randomized Controlled Pilot Study.

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    There is a widely acknowledged association between insulin resistance and obesity/type 2 diabetes (T2DM), and insulin sensitizing treatments have proved effective in preventing diabetes and inducing weight loss. Obesity and T2DM are also associated with increased inflammation. Mangosteen is a tropical tree, whose fruits—known for their antioxidant properties—have been recently suggested having a possible further role in the treatment of obesity and T2DM. The objective of this pilot study has been to evaluate safety and efficacy of treatment with mangosteen extract on insulin resistance, weight management, and inflammatory status in obese female patients with insulin resistance. Twenty-two patients were randomized 1:1 to behavioral therapy alone or behavioral therapy and mangosteen and 20 completed the 26-week study. The mangosteen group reported a significant improvement in insulin sensitivity (homeostatic model assessment-insulin resistance, HOMA-IR −53.22% vs. −15.23%, p = 0.004), and no side effect attributable to treatment was reported. Given the positive preliminary results we report and the excellent safety profile, we suggest a possible supplementary role of mangosteen extracts in the treatment of obesity, insulin resistance, and inflammation

    Impairment of methyl cycle affects mitochondrial methyl availability and glutathione level in Down's Sindrome

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    In Down's syndrome there is evidence that increased gene expression coding for specific cystathionine beta-synthase translates directly into biochemical aberrations, which result in a biochemical and metabolic imbalance of the methyl status. This event is destined to impact mitochondrial function since methylation is a necessary event in mitochondria and relies on the availability and uptake of the methyl donor S-adenosylmethionine. Indeed mitochondrial dysfunctions have been widely described in Down's syndrome, but they have never been correlated to a possible mitochondrial methyl unbalance. In the present study we find that the mitochondrial levels of S-adenosylmethionine are reduced in Down's syndrome compared to control cells demonstrating the effect of the methyl unbalance on mitochondria. The possible role of methylation in mitochondria is discussed and some preliminary results on a possible methylation target are presented
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