La lutte chimique contre la fonte des semis en pépinières forestières, intérêt du pelliculage des graines

This article is about the fourth and last year of study on the damping-off in forest nurseries. The tests conducted in 1989 on four different sites (different pedo-climatic conditions) on the Laricio pine indicated that the stripping of forest seeds is a good way to control these diseases. However, only the lack of an efficient anti-Fusarium product on the market remains a limiting factor. / Il s'agit de la 4ème et dernière année de l'étude contre les fontes des semis en pépinières forestières. Les essais menés en 1989 en 4 sites différents (contextes pédo-climatiques différents) sur pin laricio ont permis de confirmer l'intérêt du pelliculage des graines forestières pour lutter contre ces maladies de pépinières. Cependant, seule l'absence d'un produit anti-Fusarium efficace sur le marché actuel demeure le facteur limitant

Altered parabrachial nucleus nociceptive processing may underlie central pain in Parkinson’s disease.

The presence of central neuropathic pain in Parkinson’s disease suggests that the brain circuits that allow us to process pain could be dysfunctional in the disorder. However, there is to date no clear pathophysiological mechanism to explain these symptoms. In this work, we present evidence that the dysfunction of the subthalamic nucleus and/or substantia nigra pars reticulata may impact nociceptive processing in the parabrachial nucleus (PBN), a low level primary nociceptive structure in the brainstem, and induce a cellular and molecular neuro-adaptation in this structure. In rat models of Parkinson’s disease with a partial dopaminergic lesion in the substantia nigra compacta, we found that the substantia nigra reticulata showed enhanced nociceptive responses. Such responses were less impacted in the subthalamic nucleus. A total dopaminergic lesion produced an increase in the nociceptive responses as well as an increase of the firing rate in both structures. In the PBN, inhibited nociceptive responses and increased expression of GABAA receptors were found following a total dopaminergic lesion. However, neuro-adaptations at the level of dendritic spine density and post-synaptic density were found in both dopaminergic lesion groups. These results suggest that the molecular changes within the PBN following a larger dopaminergic lesion, such as increased GABAA expression, is a key mechanism to produce nociceptive processing impairment, whilst other changes may protect function after smaller dopaminergic lesions. We also propose that these neuro-adaptations follow increased inhibitory tone from the substantia nigra pars reticulata and may represent the mechanism generating central neuropathic pain in Parkinson’s disease

La lutte chimique contre la fonte des semis en pepinieres forestieres, interet du pelliculage des graines

Available from INIST (FR), Document Supply Service, under shelf-number : GR 1409 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueSIGLEFRFranc

La lutte chimique contre la fonte de semis en pepinieres forestieres : resultats obtenus en 1988

SIGLEAvailable from INIST (FR), Document Supply Service, under shelf-number : GR 1405 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc