Síndrome de Cronkhite-Canada: Cronkhite Syndrome Canada

Introdução: A Síndrome de Cronkhite-Canada é uma, apesar de rara, importante causa de alopecia, além de alterações ungueais, cutâneas e gastrointestinais, podendo as últimas serem fator de risco para o desenvolvimento de câncer do trato gastrointestinal. É possível encontrar pólipos distribuídos por todo o trato gastrointestinal. Pouco se sabe sobre sua etiologia, mas são consideradas causas infecciosas, autoimunes, alérgicas e genéticas, podendo ter como fatores predisponentes o estresse físico e mental. Apresentação do caso: Homem, 63 anos, trabalhador braçal, comparece à unidade de pronto atendimento com quadro de diarreia, náuseas, vômitos e dor em região abdominal há 2 meses, associado a perda ponderal, hipogeusia, unhas quebradiças e queda de cabelo. Endoscopia digestiva alta demonstrou polipose acentuada em estômago e duodeno. A histologia do material analisado explanou hamartomas, leve infiltração de células inflamatórias eosinofílicas, edema submucoso e dilatação de glândulas mucosas. Discussão: A SCC Apresenta um prognóstico ruim com taxa de mortalidade que ultrapassa 50% devido a doença ser progressiva com curso variável, pois a sua etiologia ainda é desconhecida. O diagnóstico depende de características patológicas, clínicas  e  endoscópicas. Porém, o diagnóstico geralmente é atrasado devido à sua raridade e à falta de um algoritmo diagnóstico. Conclusão: recomenda-se que no atendimento de um paciente apresentando as alterações descritas acima, a SCC entre como hipótese diagnóstica e seja feita uma busca ativa com exames endoscópicos e histopatológicos na suspeita de anormalidade no padrão dos pólipos. Além disso, deve ser associado a um conhecimento dermatológico amplo

Hemangioma hepático gigante: Giant hepatic hemangioma

Introdução: Devido à maior disponibilidade de exames de imagem, os tumores hepáticos estão cada vez mais presentes na prática clínica, tendo como o mais comum o hemangioma (5-20%) da população, com maior incidência em mulheres (5:1). Por ser comumente diagnosticado de maneira incidental, os hemangiomas gigantes podem cursar com sintomas condutores a suspeita. Apresentação do caso: MCRM, sexo feminino, 33 anos de idade, admitida no PS Ciams Urias Magalhães, com quadro de desconforto no abdome superior, sensação de plenitude. Negou comorbidades e uso de medicamentos. Estável hemodinamicamente, massa palpável em abdome. Tomografia de tórax evidenciou lesão de 7 cm em seu maior diâmetro, compatível com hemangioma. Discussão: o tratamento se mantém controverso. Atualmente, a conduta é expectante, exceto em casos de pacientes sintomáticos, tumores gigantes (>4 cm ), com complicações e desejo de engravidar. Nesses casos, o tratamento cirúrgico é indicado, sendo eles a ressecção hepática ou a hepatectomia. Conclusão: Geralmente, são tumores hepáticos benignos e assintomáticos, apesar de estarem sendo cada vez mais diagnosticados os hemangiomas gigantes. As complicações são raras, como rotura, abscesso, Síndrome de Kasabach-Merritt e icterícia por obstrução, ficando reservado o transplante hepático nesses casos mais graves

Brazilian Flora 2020: Leveraging the power of a collaborative scientific network

International audienceThe shortage of reliable primary taxonomic data limits the description of biological taxa and the understanding of biodiversity patterns and processes, complicating biogeographical, ecological, and evolutionary studies. This deficit creates a significant taxonomic impediment to biodiversity research and conservation planning. The taxonomic impediment and the biodiversity crisis are widely recognized, highlighting the urgent need for reliable taxonomic data. Over the past decade, numerous countries worldwide have devoted considerable effort to Target 1 of the Global Strategy for Plant Conservation (GSPC), which called for the preparation of a working list of all known plant species by 2010 and an online world Flora by 2020. Brazil is a megadiverse country, home to more of the world's known plant species than any other country. Despite that, Flora Brasiliensis, concluded in 1906, was the last comprehensive treatment of the Brazilian flora. The lack of accurate estimates of the number of species of algae, fungi, and plants occurring in Brazil contributes to the prevailing taxonomic impediment and delays progress towards the GSPC targets. Over the past 12 years, a legion of taxonomists motivated to meet Target 1 of the GSPC, worked together to gather and integrate knowledge on the algal, plant, and fungal diversity of Brazil. Overall, a team of about 980 taxonomists joined efforts in a highly collaborative project that used cybertaxonomy to prepare an updated Flora of Brazil, showing the power of scientific collaboration to reach ambitious goals. This paper presents an overview of the Brazilian Flora 2020 and provides taxonomic and spatial updates on the algae, fungi, and plants found in one of the world's most biodiverse countries. We further identify collection gaps and summarize future goals that extend beyond 2020. Our results show that Brazil is home to 46,975 native species of algae, fungi, and plants, of which 19,669 are endemic to the country. The data compiled to date suggests that the Atlantic Rainforest might be the most diverse Brazilian domain for all plant groups except gymnosperms, which are most diverse in the Amazon. However, scientific knowledge of Brazilian diversity is still unequally distributed, with the Atlantic Rainforest and the Cerrado being the most intensively sampled and studied biomes in the country. In times of “scientific reductionism”, with botanical and mycological sciences suffering pervasive depreciation in recent decades, the first online Flora of Brazil 2020 significantly enhanced the quality and quantity of taxonomic data available for algae, fungi, and plants from Brazil. This project also made all the information freely available online, providing a firm foundation for future research and for the management, conservation, and sustainable use of the Brazilian funga and flora

NEOTROPICAL CARNIVORES: a data set on carnivore distribution in the Neotropics

Mammalian carnivores are considered a key group in maintaining ecological health and can indicate potential ecological integrity in landscapes where they occur. Carnivores also hold high conservation value and their habitat requirements can guide management and conservation plans. The order Carnivora has 84 species from 8 families in the Neotropical region: Canidae; Felidae; Mephitidae; Mustelidae; Otariidae; Phocidae; Procyonidae; and Ursidae. Herein, we include published and unpublished data on native terrestrial Neotropical carnivores (Canidae; Felidae; Mephitidae; Mustelidae; Procyonidae; and Ursidae). NEOTROPICAL CARNIVORES is a publicly available data set that includes 99,605 data entries from 35,511 unique georeferenced coordinates. Detection/non-detection and quantitative data were obtained from 1818 to 2018 by researchers, governmental agencies, non-governmental organizations, and private consultants. Data were collected using several methods including camera trapping, museum collections, roadkill, line transect, and opportunistic records. Literature (peer-reviewed and grey literature) from Portuguese, Spanish and English were incorporated in this compilation. Most of the data set consists of detection data entries (n = 79,343; 79.7%) but also includes non-detection data (n = 20,262; 20.3%). Of those, 43.3% also include count data (n = 43,151). The information available in NEOTROPICAL CARNIVORES will contribute to macroecological, ecological, and conservation questions in multiple spatio-temporal perspectives. As carnivores play key roles in trophic interactions, a better understanding of their distribution and habitat requirements are essential to establish conservation management plans and safeguard the future ecological health of Neotropical ecosystems. Our data paper, combined with other large-scale data sets, has great potential to clarify species distribution and related ecological processes within the Neotropics. There are no copyright restrictions and no restriction for using data from this data paper, as long as the data paper is cited as the source of the information used. We also request that users inform us of how they intend to use the data