903 research outputs found

    Development of one-dimensional and two-dimensional computational tools that simulate steady internal condensing flows in terrestrial and zero-gravity environments

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    This dissertation presents an effective quasi one-dimensional (1-D) computational simulation tool and a full two-dimensional (2-D) computational simulation methodology for steady annular/stratified internal condensing flows of pure vapor. These simulation tools are used to investigate internal condensing flows in both gravity as well as shear driven environments. Through accurate numerical simulations of the full two dimensional governing equations, results for laminar/laminar condensing flows inside mm-scale ducts are presented. The methodology has been developed using MATLAB/COMSOL platform and is currently capable of simulating film-wise condensation for steady (and unsteady flows). Moreover, a novel 1-D solution technique, capable of simulating condensing flows inside rectangular and circular ducts with different thermal boundary conditions is also presented. The results obtained from the 2-D scientific tool and 1-D engineering tool, are validated and synthesized with experimental results for gravity dominated flows inside vertical tube and inclined channel; and, also, for shear/pressure driven flows inside horizontal channels. Furthermore, these simulation tools are employed to demonstrate key differences of physics between gravity dominated and shear/pressure driven flows. A transition map that distinguishes shear driven, gravity driven, and “mixed” driven flow zones within the non-dimensional parameter space that govern these duct flows is presented along with the film thickness and heat transfer correlations that are valid in these zones. It has also been shown that internal condensing flows in a micro-meter scale duct experiences shear driven flow, even in different gravitational environments. The full 2-D steady computational tool has been employed to investigate the length of annularity. The result for a shear driven flow in a horizontal channel shows that in absence of any noise or pressure fluctuation at the inlet, the onset of non-annularity is partly due to insufficient shear at the liquid-vapor interface. This result is being further corroborated/investigated by R. R. Naik with the help of the unsteady simulation tool. The condensing flow results and flow physics understanding developed through these simulation tools will be instrumental in reliable design of modern micro-scale and spacebased thermal systems

    Graceful labeling of triangular extension of complete bipartite graph

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    For positive integers m, n, K m,n represents the complete bipartite graph. We name the graph G = K m,n ⊙ K2 as triangular extension of complete bipartite graph K m,n , since there is a triangle hanging from every vertex of K m,n . In this paper we show that G is graceful when m = n = 2ℓ, for any integer ℓ

    L(2, 1)-labeling of circulant graphs

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    An L(2, 1)-labeling of a graph Γ is an assignment of non-negative integers to the vertices such that adjacent vertices receive labels that differ by at least 2, and those at a distance of two receive labels that differ by at least one. Let λ12(Γ) denote the least λ such that Γ admits an L(2, 1)-labeling using labels from {0, 1, . . ., λ}. A Cayley graph of group G is called a circulant graph of order n, if G = Zn. In this paper initially we investigate the upper bound for the span of the L(2, 1)-labeling for Cayley graphs on cyclic groups with “large” connection sets. Then we extend our observation and find the span of L(2, 1)-labeling for any circulants of order n

    Cadmium induces lung inflammation independent of lung cell proliferation: a molecular approach

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    <p>Abstract</p> <p>Background</p> <p>Cadmium is one of the inflammation-related xenobiotics and has been regarded as a potent carcinogen. The relationship between inflammation and cell proliferation due to chronic infection has been studied, but the mechanism is not fully clear. Though the mode of cadmium toxicity is well characterized in animal cells, still it requires some further investigations. Previously we reported that cadmium induces immune cell death in Swiss albino mice. In the present study we showed that instead of inducing cell death mechanism, cadmium in low concentration triggers proliferation in mice lung cell and our results reveals that prior to the induction of proliferation it causes severe inflammation.</p> <p>Methods</p> <p>Swiss albino mice were treated with different concentrations of cadmium to determine the LD50. Mice were subdivided (5 mice each) according to the exposure period (15, 30, 45, 60 days) and were given sub lethal dose (5 mg/Kg body weight) of cadmium chloride and ibuprofen (50 mg/Kg body weight, recommended dose) once in a week. SEM and histology were performed as evidence of changes in cellular morphology. Inflammation was measured by the expression of Cox-2 and MMPs. Expression of proinflammatory cytokines (Cox-2, IL-6), signaling and cell cycle regulatory molecules (STAT3, Akt, CyclinD1) were measured by western blot, ELISA and immunoprecipitation. Mutagenecity was evidenced by comet assay. Cell proliferation was determined by cell count, cell cycle and DNA analysis.</p> <p>Results</p> <p>Prolonged exposure of low concentration of cadmium resulted in up regulation of proinflammatory cytokines and cell cycle regulatory molecules. Though NSAIDs like Ibuprofen reduces the expression of inflammatory cytokines, but it did not show any inhibitory effect on cadmium adopted lung cell proliferation.</p> <p>Conclusion</p> <p>Our results prove that cadmium causes both inflammation and cell proliferation when applied in a low dose but proliferative changes occur independent of inflammation.</p

    Giant Magnetoimpedance (GMI) Effect and Field Sensitivity of Ferrofluid Coated Co66Fe2Si13B15Cr4 Soft Magnetic Amorphous Microwire

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    AbstractCo66Fe2Si13B15Cr4 based amorphous microwire was developed at the laboratory using in-water quenching apparatus. The field sensitivity of the wire was enhanced when coated with ferrofluids. The presence of coating also decreased the frequency of the magnetising field 5MHz to 1MHz at which the maximum GMI ratio observed

    Significance of the high charge state of projectile ions inside the target and its role in electron capture leading to target-ionization phenomena

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    The K x-ray spectra of different targets (Cu, Zn, and Ge) induced by 3-5 MeV/u Si projectile ions have been measured to determine the K-shell ionization cross section. A significant difference is observed between the measurements and theoretical estimates, with the latter being about 50% below the experimental results. This underestimation is attributed to the charge exchange from the target K shell to projectile K and L shells. Such an observation can only be possible if the projectile ions attain up to H- and He-like charge states. Corresponding projectile charge state fractions have been evaluated from the Lorentzian charge state distribution, where the mean charge state is taken from the Fermi gas model [W. Brandt, Phys. Rev. Lett. 30, 358 (1973)PRLTAO0031-900710.1103/PhysRevLett.30.358] and the width from the Novikov and Teplova approach [Phys. Lett. A 378, 1286 (2014)10.1016/j.physleta.2014.03.004]. The sum of the direct ionization cross section and K-K+K-L capture cross sections gives a good agreement with the measured cross sections. Furthermore, we have validated this methodology with available data for a Si ion on Ti target. Such results may be useful in many solid target-based applications.Fil: Chatterjee, Soumya. University Of Kalyani; IndiaFil: Sharma, Prashant. Weizmann Institute Of Science Israel; IsraelFil: Singh, Shashank. Panjab University; IndiaFil: Oswal, Mumtaz. No especifĂ­ca;Fil: Kumar, Sunil. No especifĂ­ca;Fil: Montanari, Claudia Carmen. Consejo Nacional de InvestigaciĂłnes CientĂ­ficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Ciudad Universitaria. Instituto de AstronomĂ­a y FĂ­sica del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de AstronomĂ­a y FĂ­sica del Espacio; ArgentinaFil: Mitra, D.. University Of Kalyani; IndiaFil: Nandi, T.. No especifĂ­ca
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