7,452 research outputs found
Optical properties of metal nanoparticles with arbitrary shapes
We have studied the optical properties of metallic nanoparticles with
arbitrary shape. We performed theoretical calculations of the absorption,
extinction and scattering efficiencies, which can be directly compared with
experiments, using the Discrete Dipole Approximation (DDA). In this work, the
main features in the optical spectra have been investigated depending of the
geometry and size of the nanoparticles. The origin of the optical spectra are
discussed in terms of the size, shape and material properties of each
nanoparticle, showing that a nanoparticle can be distinguish by its optical
signature.Comment: 19 pages + 8 figure
Performance Characterization of a Solenoid-type Gas Valve for the Magnetron Source at FNAL
The magnetron-style ion sources currently in operation at Fermilab
use piezoelectric gas valves to function. This kind of gas valve is sensitive
to small changes in ambient temperature, which affect the stability and
performance of the ion source. This motivates the need to find an alternative
way of feeding H2 gas into the source. A solenoid-type gas valve has been
characterized in a dedicated off-line test stand to assess the feasibility of
its use in the operational ion sources. ion beams have been extracted
at 35 keV using this valve. In this study, the performance of the solenoid gas
valve has been characterized measuring the beam current output of the magnetron
source with respect to the voltage and pulse width of the signal applied to the
gas valve.Comment: 4 pp. arXiv admin note: text overlap with arXiv:1701.0175
Implementation of Design Changes Towards a More Reliable, Hands-off Magnetron Ion Source
As the main ion source for the accelerator complex, magnetron ion
sources have been used at Fermilab since the 1970s. At the offline test stand,
new R&D is carried out to develop and upgrade the present magnetron-type
sources of ions of up to 80 mA and 35 keV beam energy in the context of
the Proton Improvement Plan. The aim of this plan is to provide high-power
proton beams for the experiments at FNAL. In order to reduce the amount of
tuning and monitoring of these ion sources, a new electronic system consisting
of a current-regulated arc discharge modulator allow the ion source to run at a
constant arc current for improved beam output and operation. A solenoid-type
gas valve feeds gas into the source precisely and independently of
ambient temperature. This summary will cover several studies and design changes
that have been tested and will eventually be implemented on the operational
magnetron sources at Fermilab. Innovative results for this type of ion source
include cathode geometries, solenoid gas valves, current controlled arc pulser,
cesium boiler redesign, gas mixtures of hydrogen and nitrogen, and duty factor
reduction, with the aim to improve source lifetime, stability, and reducing the
amount of tuning needed. In this summary, I will highlight the advances made in
ion sources at Fermilab and will outline the directions of the continuing R&D
effort.Comment: 4 pp. arXiv admin note: substantial text overlap with
arXiv:1701.0175
Improvements on the Stability and Operation of a Magnetron H- Ion Source
The magnetron H- ion sources developed in the 1970s currently in operation at
Fermilab provide beam to the rest of the accelerator complex. A series of
modifications to these sources have been tested in a dedicated offline test
stand with the aim of improving different operational issues. The solenoid type
gas valve was tested as an alternative to the piezoelectric gas valve in order
to avoid its temperature dependence. A new cesium oven was designed and tested
in order to avoid glass pieces that were present with the previous oven,
improve thermal insulation and fine tune its temperature. A current-regulated
arc modulator was developed to run the ion source at a constant arc current,
providing very stable beam outputs during operations. In order to reduce beam
noise, the addition of small amounts of N2 gas was explored, as well as testing
different cathode shapes with increasing plasma volume. This paper summarizes
the studies and modifications done in the source over the last three years with
the aim of improving its stability, reliability and overall performance.Comment: 8 pages, 19 figure
A novel integrative risk index of papillary thyroid cancer progression combining genomic alterations and clinical factors.
Although the majority of papillary thyroid cancer (PTC) is indolent, a subset of PTC behaves aggressively despite the best available treatment. A major clinical challenge is to reliably distinguish early on between those patients who need aggressive treatment from those who do not. Using a large cohort of PTC samples obtained from The Cancer Genome Atlas (TCGA), we analyzed the association between disease progression and multiple forms of genomic data, such as transcriptome, somatic mutations, and somatic copy number alterations, and found that genes related to FOXM1 signaling pathway were significantly associated with PTC progression. Integrative genomic modeling was performed, controlling for demographic and clinical characteristics, which included patient age, gender, TNM stages, histological subtypes, and history of other malignancy, using a leave-one-out elastic net model and 10-fold cross validation. For each subject, the model from the remaining subjects was used to determine the risk index, defined as a linear combination of the clinical and genomic variables from the elastic net model, and the stability of the risk index distribution was assessed through 2,000 bootstrap resampling. We developed a novel approach to combine genomic alterations and patient-related clinical factors that delineates the subset of patients who have more aggressive disease from those whose tumors are indolent and likely will require less aggressive treatment and surveillance (p = 4.62 × 10-10, log-rank test). Our results suggest that risk index modeling that combines genomic alterations with current staging systems provides an opportunity for more effective anticipation of disease prognosis and therefore enhanced precision management of PTC
Potencial do uso de entomopatógenos no controle de pragas da soja e seletividade de agrotóxicos para fungos entomopatogênicos.
Reflexiones y noticias sobre escultores y ensambladores indígenas en Bolivia y Perú, siglos XVI y XVII
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