812 research outputs found

    Asymptotic distribution of least squares estimators for linear models with dependent errors : regular designs

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    In this paper, we consider the usual linear regression model in the case where the error process is assumed strictly stationary. We use a result from Hannan, who proved a Central Limit Theorem for the usual least squares estimator under general conditions on the design and on the error process. We show that for a large class of designs, the asymptotic covariance matrix is as simple as the independent and identically distributed case. We then estimate the covariance matrix using an estimator of the spectral density whose consistency is proved under very mild conditions.Comment: 31 page

    Indigenous Policy Conference Summary Report: Beyond Reconciliation

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    The School of Public Policy (SPP) at the University of Calgary organized a conference to announce the establishment of its Indigenous Policy program and to share knowledge and stories about policy issues critical to Indigenous Peoples in Canada. The conference, titled “Beyond Reconciliation,” was held at the University of Calgary Downtown Campus on Nov. 21, 2016 and was attended by 73 participants. This included Indigenous elders, chiefs and leaders, and members of Indigenous organizations, including a women’s group. Also included were members of universities and academic institutions, including students; industry representatives from the oil and gas, pipeline, forestry, electricity, legal and financial sectors; as well as representatives from government and regulatory agencies. The purpose of the conference was established with the following abstract, which was circulated to speakers and participants: The School of Public Policy is establishing a new Indigenous Policy program in order to produce widely disseminated research and engage in outreach that covers an array of policy areas, such as health, education, self-government, and natural resource development. The program will directly engage Indigenous communities in the search for original, long-term, and evidence-based solutions, as part of an effort to improve our national capacity in problem-solving and policy development. The conference will provide a platform to launch the program, showcasing preliminary research and providing a venue for discussion of policy solutions. The conference included three moderated panel sessions and a keynote speaker.1 The first panel considered business and entrepreneurship in Indigenous communities; the second panel showcased case studies that are examining the experiences of Indigenous communities with natural resource development projects, and particularly their experiences with consultation and engagement. The final panel focused on ways of improving the consultation and engagement process with Indigenous communities. This report summarizes both the presentations and the major themes explored at the conference. The purpose is to capture the ideas and debates emerging from the conference, and provide an overview of the day for interested policy-makers and the public. The report begins with an outline of the agenda, before summarizing each of the panel sessions and the keynote speaker’s presentation. The concluding section provides a discussion of the key themes emerging from the conference and next steps for policy-makers and researchers. Three students enrolled in the SPP’s Master of Public Policy program took detailed notes throughout the day. The authors thank them for their thoroughness. The student notes and the authors’ notes were used to inform this report

    Le jeu comme outil thérapeutique et la thérapie cognitivo-comportementale : aider les enfants ayant des troubles du comportement

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    La thĂ©rapie par le jeu est une approche qui semble controversĂ©e en service social. MalgrĂ©, ses nombreux avantages en intervention avec les enfants, plusieurs se demandent si elle est prouvĂ©e scientifiquement. Dans ce mĂ©moire, je cherche Ă  montrer comment les outils thĂ©rapeutiques en thĂ©rapie par le jeu juxtaposĂ© Ă  la thĂ©rapie cognitivo-comportementale aident les enfants Ă  surmonter leurs difficultĂ©s de comportements relationnels liĂ©es Ă  des situations de vie. Afin d’en faire l’expĂ©rience, j’ai choisi de faire un stage spĂ©cialisĂ© de 450 heures durant lequel j’ai pu faire de l’intervention auprĂšs de sept enfants ĂągĂ©s entre 5 et 12 ans et prĂ©sentant des difficultĂ©s de comportement. Dans cet essai de stage, seulement deux de ces cas sont prĂ©sentĂ©s afin qu’on puisse voir en dĂ©tail les interventions effectuĂ©es et les rĂ©sultats atteints. Dans ces deux cas, comme d’ailleurs dans les autres situations d’intervention, la thĂ©rapie par le jeu et la thĂ©rapie cognitivo-comportementale sont une excellente combinaison qui permet Ă  l’enfant de dĂ©velopper divers outils afin de surmonter ses difficultĂ©s de comportement et dĂ©velopper un sentiment de confiance et d’appartenance dans le processus de relation d’aide. J’ai pu aussi remarquer l’importance d’impliquer les parents de la premiĂšre Ă  la derniĂšre session d’intervention. Tous ces Ă©lĂ©ments augmentent les probabilitĂ©s de rĂ©ussite en intervention.MaĂźtrise en Service Socia

    Path constraints in semistructured data

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    International audienceWe consider semistructured data as multirooted edge-labelled directed graphs, and path inclusion constraints on these graphs. A path inclusion constraint pnot precedes, equalsq is satisfied by a semistructured data if any node reached by the regular query p is also reached by the regular query q. In this paper, two problems are mainly studied: the implication problem and the problem of the existence of a finite exact model. - We give a new decision algorithm for the implication problem of a constraint pnot precedes, equalsq by a set of bounded path constraints pinot precedes, equalsui where p, q, and the pi's are regular path expressions and the ui's are words, improving in this particular case, the more general algorithms of S. Abiteboul and V. Vianu, and N. Alechina et al. In the case of a set of word equalities ui≡vi, we provide a more efficient decision algorithm for the implication of a word equality u≡v, improving the more general algorithm of P. Buneman et al. We prove that, in this case, implication for nondeterministic models is equivalent to implication for (complete) deterministic ones. - We introduce the notion of exact model: an exact model of a set of path constraints Click to view the MathML source satisfies the constraint pnot precedes, equalsq if and only if this constraint is implied by Click to view the MathML source. We prove that any set of constraints has an exact model and we give a decidable characterization of data which are exact models of bounded path inclusion constraints sets

    Phytostabilisation d'un site pollué par les éléments traces : opération pilote et pérennité du traitement

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    National audienceGrùce à l'utilisation combinée de plantes et d'agents immobilisants, la phytostabilisation assistée limite les risques associés à un sol contaminé en réduisant la biodisponibilité des polluants. Le rÎle des plantes est de réduire le lessivage et l'érosion. En Europe et dans le monde, de nombreux sites ont déjà été phytostabilisés avec succÚs. Cependant, peu de projets de phytostabilisation associent une surface et une durée d'expérimentation suffisantes pour établir l'efficacité sur le long terme et en conditions réelles d'une telle pratique pour la gestion d'un site pollué. La nécessité de conduire des opérations pilotes sur une longue durée a été ainsi mise en avant par la communauté scientifique. L'objectif de ce projet mené sur un dispositif pilote mis en place en 2002 est d'estimer l'efficacité dans le temps d'une phytostabilisation assistée appliquée à un sédiment pollué par les éléments traces (Cd, Zn, Pb, Cu, As). Les paramÚtres suivis dans cette étude sont liés aux plantes initialement semées, aux espÚces végétales venues spontanément coloniser le dispositif, aux agents immobilisants utilisés et aux caractéristiques physico-agronomiques de la matrice polluée. Une synthÚse des résultats obtenus sur 7 années de suivi sera présentée lors du colloque

    Clinical behavior and outcomes of breast cancer in young women with germline BRCA pathogenic variants

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    CĂ ncer de mama; GenĂštica del cĂ ncerCĂĄncer de mama; GenĂ©tica del cĂĄncerBreast cancer; Cancer geneticsYoung breast cancer (BC) patients carrying a germline BRCA pathogenic variant (mBRCA) have similar outcomes as non-carriers. However, the impact of the type of gene (BRCA1 vs. BRCA2) and hormone receptor status (positive [HR+] vs. negative [HR−]) on clinical behavior and outcomes of mBRCA BC remains largely unknown. This is an international, multicenter, hospital-based, retrospective cohort study that included mBRCA patients diagnosed, between January 2000 and December 2012, with stage I–III invasive early BC at age ≀40 years. From 30 centers worldwide, 1236 young mBRCA BC patients were included. Among 808 and 428 patients with mBRCA1 or mBRCA2, 191 (23.6%) and 356 (83.2%) had HR+tumors, respectively (P < 0.001). Median follow-up was 7.9 years. Second primary BC (P = 0.009) and non-BC malignancies (P = 0.02) were more frequent among mBRCA1 patients while distant recurrences were less frequent (P = 0.02). Irrespective of hormone receptor status, mBRCA1 patients had worse disease-free survival (DFS; adjusted HR = 0.76, 95% CI = 0.60–0.96), with no difference in distant recurrence-free interval (DRFI) and overall survival (OS). Patients with HR+ disease had more frequent distant recurrences (P < 0.001) and less frequent second primary malignancies (BC: P = 0.005; non-BC: P = 0.18). No differences in DFS and OS were observed according to hormone receptor status, with a tendency for worse DRFI (adjusted HR = 1.39, 95% CI = 0.94–2.05) in patients with HR+ BC. Type of mBRCA gene and hormone receptor status strongly impact BC clinical behavior and outcomes in mBRCA young patients. These results provide important information for patients’ counseling on treatment, prevention, and surveillance strategies.This study received partial financial support by grants from the Italian Ministry of Health - 5 × 1000 funds 2017 (no grant number), the Italian Association for Cancer Research (AIRC; MFAG 2020 ID 24698), and “Les Amis de l’Institut Bordet” foundation (no grant number). The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. M.L. acknowledges the support from the European Society for Medical Oncology (ESMO) for a Translational Research Fellowship at the Institut Jules Bordet in Brussels (Belgium) at the time of study conduction. K.P. acknowledges the support from a predoctoral clinical ‘KOOR’ mandate from the University Hospitals Leuven (Leuven, Belgium). F.P.D. acknowledges the support for a postdoctoral clinical mandate (2017-034) from the not-for-profit organization ‘Foundation Against Cancer’ (Brussels, Belgium). A.H.P. acknowledges the support from Susan G. Komen and Breast Cancer Research Foundation (BCRF). J.H. acknowledges the support from the Carlos III National Health Institute funded by FEDER funds—a way to build Europe (PI16/11363). This research was presented in the Poster Spotlight session at the 2020 San Antonio Breast Cancer Symposium (SABCS), San Antonio, TX, United States of America, on 8–12 December 2020

    SERG Final report: Ecosystemic impacts of forest tent caterpillar outbreaks

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    The forest tent caterpillar (Malacosoma disstria) is a significant defoliator of hardwoods throughout Canada. Historically, infestations usually collapsed after one or two years of defoliation, but longer and more severe outbreaks have been observed in recent years, leading to mortality of both sugar maple and trembling aspen, and making the forest tent caterpillar another pest whose impacts are increasing under a changing climate. This project examines how forest tent caterpillar outbreaks influence soil ecosystems, in both temperate deciduous and mixed boreal forests. We will assess inputs to soil ecosystems associated with forest tent caterpillar outbreaks and determine impacts on soil arthropod communities and tree regeneration. We also examine the different sources of mortality of the forest tent caterpillar colonies during and after the outbreak. It will thus provide empirical data to assess effects of forest tent caterpillar outbreaks on forest ecosystems and successional processes as well as population dynamics throughout the outbreaking cycle. Results suggest that defoliation favours the growth of non-host saplings. They also suggest that sources of mortality change during the different parts of the outbreak. Results will also contribute to the development of novel silvicultural approaches taking into account the effects of forest tent caterpillar outbreaks on forest regeneration and the need to keep process promoting regulation of forest tent caterpillar populations. La livrĂ©e des forĂȘts (Malacosoma disstria) est un dĂ©foliateur important des forĂȘts feuillues du Canada. Dans le passĂ©, les Ă©pidĂ©mies s’effondraient gĂ©nĂ©ralement aprĂšs une ou deux annĂ©es de dĂ©foliation sans causer de dommages significatifs Ă  la forĂȘt, mais l’observation rĂ©cente d’épidĂ©mies plus longues et plus sĂ©vĂšres, suivies de mortalitĂ© des tiges de peuplier faux-tremble et d’érable Ă  sucre, suggĂšrent que les impacts de la livrĂ©e des forĂȘts, comme de plusieurs autres insectes ravageurs, augmentent en raison des changements climatiques. Ce projet examine les effets d’une Ă©pidĂ©mie de livrĂ©e des forĂȘts sur l’écosystĂšme du sol dans deux Ă©cosystĂšmes forestiers: la forĂȘt feuillue et la forĂȘt borĂ©ale mixte. Nous examinerons les apports en nutriments au sol associĂ©s aux Ă©pidĂ©mies de livrĂ©e et Ă©valuerons les effets sur la communautĂ© d’arthropodes du sol et sur la rĂ©gĂ©nĂ©ration des arbres. Nous avons aussi examinĂ© les sources de mortalitĂ© des colonies de livrĂ©e des forĂȘts durant et aprĂšs l’épidĂ©mie. Les rĂ©sultats fourniront des donnĂ©es empiriques pour Ă©valuer les impacts des Ă©pidĂ©mies de livrĂ©e sur les Ă©cosystĂšmes forestiers et les processus de succession Ă©cologiques ainsi que les dynamiques de populations Ă  travers les cycles Ă©pidĂ©miques. Les rĂ©sultats suggĂšrent que la dĂ©foliation peut bĂ©nĂ©ficier la croissance des jeunes arbres non-hĂŽtes. Ils suggĂšrent aussi que les sources de mortalitĂ© diffĂšrent lors des diffĂ©rentes parties du cycles Ă©pidĂ©miques. Les rĂ©sultats contribueront aussi au dĂ©veloppement d’approches sylvicoles qui prennent en considĂ©ration le rĂŽle de la livrĂ©e dans la rĂ©gĂ©nĂ©ration des forĂȘts

    XML Security Views Revisited

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    International audienceIn this paper, we revisit the view based security framework for XML without imposing any of the previously considered restrictions on the class of queries, the class of DTDs, and the type of annotations used to dene the view. First, we show that the full class of Regular XPath queries is closed under query rewriting. Next, we address the problem of constructing a DTD that describes the view schema, which in general needs not be regular. We propose three dierent methods of ap- proximating the view schema and we show that the produced DTDs are indistinguishable from the exact schema (with queries from a class speci c for each method). Finally, we investigate problems of static analysis of security access specications

    Static analysis of XML security views and query rewriting

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    International audienceIn this paper, we revisit the view based security framework for XML without imposing any of the previously considered restrictions on the class of queries, the class of DTDs, and the type of annotations used to define the view. First, we study {\em query rewriting} with views when the classes used to define queries and views are Regular XPath and MSO. Next, we investigate problems of {\em static analysis} of security access specifications (SAS): we introduce the novel class of \emph{interval-bounded} SAS and we define three different manners to compare views (i.e. queries), with a security point of view. We provide a systematic study of the complexity for deciding these three comparisons, when the depth of the XML documents is bounded, when the document may have an arbitrary depth but the queries defining the views are restricted to guarantee the interval-bounded property, and in the general setting without restriction on queries and document
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