Interleukin-6 in Spontaneous and Induced Vaginal Birth and Neonatal Outcomes: A Cross-Sectional Study

Introduction: The detailed mechanisms fundamentally the onset of spontaneous labor at term remain obscure. Delayed labor means slower progress of the birth process and is associated with childbirth problems and negative birth feelings, resulting in subsequent pregnancy and labor. Inflammatory mechanisms are thought to play a vital role in the physiology of parturition and labor in pre-term and spontaneous term birth. Studies indicated that the mode of birth and labor change interleukin-6 concentrations in maternal and fetal sections. The immunobiological role of inflammatory cytokines in parturition and the onset of spontaneous labor at term, especially without exogenic motivation, remain unspecified yet. The specific role of Interleukin - 6 (IL - 6) in the biosynthesis of prostaglandins, myometrium contractions, cervix ripening, and finally, its role in the process of labor is reported in studies. According to the changes in the physiology of normal birth in induced labor, this study aimed to compare the mean level of IL-6 in pregnancies terminated by selective induction or spontaneous vaginal birth and neonatal outcome. Methods: This cross-sectional study was conducted on two groups of 40 women with spontaneous and induced birth. All pregnancies were term without clinical or obstetric complications. The enzyme-connected immunosorbent assay measured the level of IL - 6 in the umbilical cord. The obtained data were analyzed by SPSS 22 software. Results: The mean level of IL-6 in the umbilical cord was not significantly different in spontaneous (250.20 ± 39.36 pg./ml) and induced labor (240.97 ± 39.06 pg./ml) (P = 0.847). In the spontaneous birth group, the first and fifth minute Apgar scores were higher than the induced labor group (P = 0.021). None of the infants required resuscitation or NICU hospitalization in the neonatal unit. Approximately 97.5% of infants were breastfed in the induced birth group. Only one of the newborns in the induced birth group had jaundice and underwent phototherapy for 8 hours at home. In this study, there was found no association between IL - 6 and pregnancy/infant variables. Conclusions: Our results indicate that the birth method (induced and spontaneous) had no effect on the level of IL-6 in the umbilical cord blood, but the birth method had just a significant effect on the Apgar score. Induction of labor is associated with adverse birth outcomes. This study investigated interleukin-6 in cord blood in term newborns depending on the mode of delivery and labor. Delayed labor means slower progress of the birth process and is associated with childbirth problems and negative birth feelings, which can have consequences on subsequent pregnancy and labor. We determined whether normal spontaneous birth and induced birth at term was associated with poor newborns outcomes. Current study was a different view helping future studies to investigate other aspects of post term pregnancy and supporting physiological parturitio

Arbaeen Ceremony and its Impact on Suburban Road Accidents in Western of Iran

سابقه و هدف: مراسم اربعین حجم ترافیک جاده‌های استان کرمانشاه را افزایش داده‌است بنابراین تحلیل تصادف‌ها می‌تواند سیاست‌گذاری و برنامه‌های پیشگیری حوادث ترافیکی را ارتقاء دهد. هدف این مطالعه تحلیل حوادث ترافیکی جاده‌های برون شهری استان کرمانشاه با استفاده از GIS در سفرهای اربعین بود. روش‌ بررسی: مطالعه به صورت توصیفی - تحلیلی در سال 1398 و در محیط نرم‌افزار ArcGIS10.6 انجام گردید. مطالعه در سه فاز جمع‌آوری داده‌ها، آماده‌سازی پایگاه داده و تحلیل داده‌ها انجام شد. در فاز اول لایه‌های وکتوری مطالعه ایجاد و داده‌های تصادف‌های سال 1397 از پلیس راهور جمع‌آوری شدند، سپس داده‌های تصادف‌های مربوط به ایام اربعین (27/07/1397 الی 11/8/1397) از این مجموعه استخراج شدند. در فاز دوم نقشه محیط مطالعه به ArcGIS 10.6 وارد و لایه‌های وکتوری و جداول توصیفی آنها ایجاد شدند. فاز سوم، تحلیل داده‌ها جهت شناسایی علت، نوع و حالت تصادف‌ها، نقاط حادثه خیز و توزیع تصادف انجام شد. نتایج: در ایام اربعین سال 1397 تعداد 149 تصادف اتفاق افتاده بوده که در نتیجه آن 20 فوتی و 129 جرحی داشت.  تصادف خودروهای شخصی با 110، برخورد چند وسیله با 65 و تجاوز از سرعت مطمئنه با 54 مورد بیشترین نوع وسیله، حالت و علت تصادف‌ها بودند. نتیجه‌گیری: تردد زیاد وسایل نقلیه در ایام اربعین نیاز به برنامه‌ریزی دقیق دارد. بنابراین بهبود زیرساخت‌ها باعث بهبود وضعیت تردد و کاهش حوادث ترافیکی می‌گردد. همچنین توزيع مناسب منابع و تسهيلات، امدادرسانی و پاسخگويي‌ سريع در مسیرهای تردد اربعین بسيار ضروري است. How to cite this article: Mohammadi A, Mohammadi R, Shahsavari S, Shabani N. Arbaeen Ceremony and its Impact on Suburban Road Accidents in Western of Iran. Irtiqa Imini Pishgiri Masdumiyat. 2022;10(2): 124-30.Background and Objectives: The Arbaeen ceremony has increased the volume of road traffic in Kermanshah province, so accident analysis can improve policy-making and traffic accident prevention programs. The purpose of this study was to analyze traffic accidents on suburban roads of Kermanshah province using GIS in Arbaeen trips. Materials and Methods: This applied study was performed descriptively-analytically in 2019 in the ArcGIS 10.6 software environment. The study was conducted in three phases: data collection, database preparation, and data analysis. In the first phase, the vector layers of the study were created and the accident data of 2018 were collected from Police Office, then the accident data related to the Arbaeen days (13.10.2018- 2.11.2018) were extracted from this collection. In the second phase, the study environment map was entered into ArcGIS 10.6 and their vector layers and descriptive tables were created. Phase 3, data analysis was performed to identify the cause, type, and condition of accidents, accident hotspots, and distribution. Results: In the Arbaeen days of 2018, 149 accidents occurred, as a result of which there were 20 deaths and 129 injuries. Personal vehicle crashes with 110, multi-vehicle collisions with 65, and speeding with 54 were the most common types of vehicles, modes, and causes of accidents.  Conclusion: High vehicle traffic in the Arbaeen days requires careful planning. Therefore, improving the infrastructure will improve the traffic situation and reduce traffic accidents. Proper distribution of resources and facilities, relief, and rapid response in Arbaeen traffic routes are also essential. How to cite this article: Mohammadi A, Mohammadi R, Shahsavari S, Shabani N. Arbaeen Ceremony and its Impact on Suburban Road Accidents in Western of Iran. Irtiqa Imini Pishgiri Masdumiyat. 2022;10(2): 124-30

Biclustering Algorithm for Embryonic Tumor Gene Expression Dataset: LAS Algorithm

An important step in considering of gene expression data is obtained groups of genes that have similarity patterns. Biclustering methods was recently introduced for discovering subsets of genes that have coherent values across a subset of conditions. The LAS algorithm relies on a heuristic randomized search to find biclusters. In this paper, we introduce biclustering LAS algorithm and then apply this procedure for real value gene expression data. In this study after normalized data, LAS performed. 31 biclusters were  discovered that 26 of them were for positive gene expression values and others were for negative. Biological validity for LAS procedure in biological process, in molecular function and in cellular component were 77.96% , 62.28% and 74.39% respictively. The result of biological validation of LAS algorithm in this study had shown LAS algorithm effectively convenient in discovering good biclusters

Correlation between inner strength and health-promoting behaviors in women with heart failure

Introduction: Inner strength is a factor for mental health and well-being and, consequently, a dynamic component of holistic healing. Health-promoting behaviors are appropriate activities to improve health status and prevent the progression of the functional defect resulting from heart failure. The present study aimed to determine the correlation between inner strength and health-promoting behaviors in women with heart failure referred to hospitals affiliated with Shahid Beheshti University of Medical Sciences (SBMU) in 2013. Methods: In this cross-sectional study, 145 women with hearth failure were selected through convenient sampling from the clients referred to hospitals affiliated with SBMU. The data collection tool included a three- section questionnaire of personal characteristics, inner strength, and health-promoting life profile II (HPLP II). The data analysis used descriptive statistical tests and Pearson correlation coefficient through SPSS version 20. Results: A direct significant correlation was found between inner strength and all dimensions of health- promoting behaviors and overall health-promoting behaviors (p=0.000) as well as between all dimensions of inner strength (except for the dimension of knowing and searching with physical activity and the dimension of connectedness with personal accountability in healthcare as well as connectedness with physical activity) with health-promoting behaviors (p=0.000 to p=0008). Conclusion: To improve the level of health and well-being and reduce the costs of care services in women with health failure, close attention should be paid to developing and empowering their inner strength

The correlation of inner strength and health promoting behaviors in women with heart failure

AbstractBackgroundHealth promoting behaviors are appropriate actions to promote health and prevent further decompensation due to heartfailure. Inner strength is a factor of psychological health and well- being and therefore is a dynamic element in holisticrecovery. The aim of this study was to determine the correlation of inner strength and health promoting behaviors inwomen with heart failure referring to hospital affiliated with Beheshti University of Medical Sciences in 2013.Materials and methodsIn this descriptive-Correlation Study, 145 women with heart failure referring to hospital affiliated with ShaheedBeheshti Medical University were selected by convenience sampling method. A 3-part questionnaire includingdemographics, inner strength questionnaire and Health-promoting lifestyle profile II was used for data collection. Datawere analyzed with SPSS 20.FindingThere was significant correlation between inner strength and health promoting behaviors dimensions and healthpromoting behaviors in general (p<0.001) as well as between all dimensions of inner strength (except knowing andSearching dimension with physical activity, connectedness dimension with health responsibility and connectednessdimension with physical activity) (p<0.01).ConclusionThere is significant correlation between inner strength and health promoting behaviors of women with heart failure.Therefore, attention to enhancement of inner strength by nurses seems necessary to improve the health in women withheart failure.Keywords:Inner strength, Health promoting behaviors, Women, Heart failur

Comparing the effects of pethidine and diclofenac suppository on patients with renal colic in the emergency department

Objective: Renal colic is a common cause of emergency room visits. Due to the spontaneous passage of more than 90% of kidney stones, treatment in the emergency department (ED) is limited to pain control. Analgesics currently used are selected based on physician experiences and various theories from different sources. The aim of this study was to compare the common drugs (pethidine and diclofenac) used for renal colic in Iran. Methods: In this single-blinded randomized clinical trial, 90 patients with renal colic who referred to the ED of Imam Reza hospital in Kermanshah were randomly assigned to each of 3 treatments including pethidine suppository (50 mg, iv), diclofenac suppository (50 mg), and a combination of pethidine and diclofenac suppository. In this regard, the response to treatment and duration of hospitalization were compared. Results: The best medicine to relieve pain intensity in patients under 25 years was diclofenac suppository. In patients in the age range of 25-45 years, pethidine and diclofenac were the best choice. Conversely, in patients older than 45 years, pethidine was the best treatment. We could also observe a decrease in the length of hospitalization in patients who received pethidine. Conclusion: It can be concluded that morphine is more appropriate to control pain and reduce the length of hospitalization in patients with renal colic. Clinical Trial Registration: irct.ir, Identifier: IRCT2010121453

Comparison of Physical Activity in Fertile and Infertile Couples in Kermanshah, Iran during 2013

Abstract:Background and aimInfertility is a major reproductive health problem that affect 10%-15% of couples. According to the WorldHealth Organization, there are currently 50-80 million infertile couples in the world. Physical activity is alife style factor with possible positive or negative effects on reproductive. The aim of this study was tocompare the physical activity of fertile and infertile couples in Kermanshah, Iran during 2013.Materials and MethodsThis was a descriptive comparative study. The case group consisted of 118 infertile couples attendingMotazedi Infertility Center. One hundred and eight fertile couple attending to six public health centers inKermanshah, Iran, were the controls. The sampling method was convenience sampling. Data were collectedby a questionnaire. The questionnaire was consisted of two section. The first section was demographic andfertility characteristics and the second section was international physical activity questionnaire. The data ispresented by descriptive statistics and analyzed with logistic regression, independent t-test, chi-square, andgamma tests using SPSS v16.ResultsThe result of this study showed that the majority of fertile women(86.1%), infertile women(73.1%), fertilemen(87%) and infertile men(96.3%) had moderate level of physical activity. There was a significantdifference between fertile and infertile men and women in terms of physical activity. The fertile and infertilecouples, also, have significant difference in physical activity(P<0/05).ConclusionsGiven the importance of physical activity on reproductive health and significant difference of physicalactivity between fertile and infertile couples in this study, it seems that more attention should be paid tolifestyle behaviors, especially in infertile couples.KeywordsLife Style; Physical Activity; Fertility, Ira

Comparison of lifestyle in fertile and infertile couples in Kermanshah during 2013

Background: Infertility is a major reproductive health in gynecology. According to the world health organization, there are currently 50-80 million infertile couples in the world. Objective: Considering the critical effects of lifestyle on reproductive health, this study aimed to compare the lifestyle of fertile and infertile couples in Kermanshah during 2013. Materials and Methods: This research is a descriptive cross sectional study that was done on 216 fertile and infertile couples attending Infertility Center and six medical centers that were selected through the convenience sampling. Data were collected using a researcher-made questionnaire containing demographic and fertility-related information and also lifestyle items on nutrition, physical activity, perceived social support, responsibility for health, and inappropriate health behaviors. Descriptive statistics, logistic regression analysis, independent t, chi-square and Generalized Estimating equation were performed to analyze the data. Results: Fertile and infertile women (86.1% and 73. 1% respectively, p= 0. 03) as well as fertile and infertile men were significantly different in terms of physical activity (87% and 96.3% p<0.001, respectively) and perceived social support (p<0.001). Moreover, there was a significant difference between fertile and infertile women in nutrition (p<0.001). Similar differences were observed in responsibility for health and inappropriate health behaviors between fertile and infertile men. However, all of the dimensions of lifestyle, except nutrition, were significantly different between fertile and infertile couples. Conclusion: As lifestyle plays a crucial role in reproductive health, the inappropriate lifestyle of infertile couples has to be modified through effective measures such as awareness promotion, behavioral changes, and development of a healthy environment