含フッ素テトラアリールホウ酸イオンによって疎水性溶媒中に可溶化されたアルカリ金属イオンの反応性の研究

序論 第1章 かさ高い脂溶性アニオン種の合成 第2章 アゾ化スピロピランの合成 第3章 アゾ色素の吸収スペクトルに及ぼすアルカリ金属ホウ酸塩の効果 第4章 疎水性溶媒中におけるベタイン色素の吸収スペクトルに及ぼすアルカリ金属ホウ酸塩の効果 第5章 疎水性溶媒中のスピロピラン型色素の吸収スペクトルに及ぼすアルカリ金属ホウ酸塩の効果 第6章 疎水性溶媒中に可溶化されたアルカリ金属イオンによるトリチルカチオンの発生 第7章 アルカリ金属ホウ酸塩を触媒に用いた炭素一炭素結合形成反応 結論Made available in DSpace on 2012-07-04T00:33:48Z (GMT). No. of bitstreams: 3 sonoda1.pdf: 12097412 bytes, checksum: 82b4e490350fa89d532b604c67a574fd (MD5) sonoda2.pdf: 11959572 bytes, checksum: 72aa40294400f79cbf5d72e7d534462d (MD5) sonoda3.pdf: 10894210 bytes, checksum: 6847c70bbc26e92aec1cd968875446e3 (MD5) Previous issue date: 1993-03-2

Antibacterial Effect of Amino Acid-Silver Complex Loaded Montmorillonite Incorporated in Dental Acrylic Resin

Several dental materials contain silver for antibacterial effect, however the effect is relatively low. The reason for the lower antibacterial efficacy of silver is considered to be the fact that silver ions bind to chloride ions in saliva. To develop new effective silver antibacterial agents that can be useful in the mouth, we synthesized two novel amino acid (methionine or histidine)-silver complexes (Met or His-Ag) loaded with montmorillonite (Mont) and analyzed their antibacterial efficacy. At first the complexes were characterized using nuclear magnetic resonance (NMR), and amino acid-Ag complex-loaded Mont (amino acid-Ag-Mont) were characterized using X-ray diffraction (XRD) and scanning electron microscopy (SEM). The antibacterial efficacy of these materials in dental acrylic resin was then investigated by bacterial growth measurement using a spectrophotometer. As controls, commercially available silver-loaded zeolite and silver-zirconium phosphate were also tested. Dental acrylic resin incorporating His-Ag-Mont strongly inhibited Streptococcus mutans growth. This was explained by the fact that His-Ag complex revealed the highest amounts of silver ions in the presence of chloride. The structure of the amino acid-Ag complexes affected the silver ion presence in chloride and the antibacterial efficacy. His-Ag-Mont might be used as antibacterial agents for dental materials