996 research outputs found
Research Progress and Development of Sapphire Fiber Sensor 1
Abstract: Sapphire fiber thermometers have become a new potential option in the field of high-temperature measurements. Recent research progress of sapphire fiber sensors is summarized; operational principles, advantages, disadvantages, and applications of sapphire fiber sensors are introduced. Research has shown that sapphire fiber sensors can be used to accurately measure very high temperatures in harsh environments and has been widely applied in fields such as aviation, metallurgy, the chemical industry, energy, and other high temperature measurement areas. Sapphire optical fiber temperature measurement technology will move toward miniaturization, intelligence following the advances in materials, micro-fabrication and communication technologies. Copyright © 2014 IFSA Publishing, S. L
Kinetic Approaches to Understanding the Mechanisms of Fidelity of the Herpes Simplex Virus Type 1 DNA Polymerase
We discuss how the results of presteady-state and steady-state kinetic analysis of the polymerizing and excision activities of herpes simplex virus type 1 (HSV-1) DNA polymerase have led to a better understanding of the mechanisms controlling fidelity of this important model replication polymerase. Despite a poorer misincorporation frequency compared to other replicative polymerases with intrinsic 3′ to 5′ exonuclease (exo) activity, HSV-1 DNA replication fidelity is enhanced by a high kinetic barrier to extending a primer/template containing a mismatch or abasic lesion and by the dynamic ability of the polymerase to switch the primer terminus between the exo and polymerizing active sites. The HSV-1 polymerase with a catalytically inactivated exo activity possesses reduced rates of primer switching and fails to support productive replication, suggesting a novel means to target polymerase for replication inhibition
AST-GIN: Attribute-Augmented Spatial-Temporal Graph Informer Network for Electric Vehicle Charging Station Availability Forecasting
Electric Vehicle (EV) charging demand and charging station availability
forecasting is one of the challenges in the intelligent transportation system.
With the accurate EV station situation prediction, suitable charging behaviors
could be scheduled in advance to relieve range anxiety. Many existing deep
learning methods are proposed to address this issue, however, due to the
complex road network structure and comprehensive external factors, such as
point of interests (POIs) and weather effects, many commonly used algorithms
could just extract the historical usage information without considering
comprehensive influence of external factors. To enhance the prediction accuracy
and interpretability, the Attribute-Augmented Spatial-Temporal Graph Informer
(AST-GIN) structure is proposed in this study by combining the Graph
Convolutional Network (GCN) layer and the Informer layer to extract both
external and internal spatial-temporal dependence of relevant transportation
data. And the external factors are modeled as dynamic attributes by the
attribute-augmented encoder for training. AST-GIN model is tested on the data
collected in Dundee City and experimental results show the effectiveness of our
model considering external factors influence over various horizon settings
compared with other baselines.Comment: 10 pages; 17 figures; Under review for IEEE Transaction on Vehicular
Technolog
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