6 research outputs found
A review on triterpenoids from plant sources as potential antiviral agents
Viral infections are considered as leading a health issue globally. Numerous numbers of biologically active anti-viral agents have been identified from plants and other organisms. Particularly, terpenoids are a major component of the plant secondary metabolites and a complexity of these structures is accompanied by the potency of their biological activities. It is believed that most of the terpenoids possess the bioactivity against viral infections and cancer diseases. Hence, affected by the pressing a need elevated by the spreading of seriously life-threaten viruses, this review highlights the importance of terpenoids and their activity as antiviral agents that can be employed to treat current lethal diseases such as HIV, H1N1, SARS-CoV and HSV
Mycorrhiza and Lichens as Two Models of Fungal Symbiosis
Fungi have evolved many symbioses including different eukaryotes and prokaryotes. Mutualism is one of the symbioses and here both symbionts benefit from the interaction. The most common mutualistic relationships involving fungi are mycorrhiza and lichens. A mycorrhiza is a symbiotic relationship between a roots of a plant and a fungus while lichen associates between a fungus and an algae. Many studies have performed to investigate these symbiotic relationships in depth, however, still have some debates on them, though many taxonomists rely on genetic analyses besides with traditional morphological data. In our study, it highlights the nature, importance, nutritional and pharmaceutical uses, and applications of these mysterious dual between fungi and plant and/or algae
Biologically active orcinol-based secondary metabolites originated from lichens
Lichens have attracted considerable interest since ancient time due to their medicinal properties. Lichen produce a variety of orcinol-based compounds such as xanthones, anthraquinones, dibenzofurans, depsides, and depsidones. Several related compounds have shown potent bioactivities as antiviral, antioxidant, anti-herbivore, insecticidal, antifungal, and anticancer. Lichens have been employed as traditional medicines, and these are continuing to be of great interest for their biotechnological potential. The purpose of this review was to systematically evaluate the literature on the orcinol based biologically active secondary metabolites of lichen
A review on triterpenoids from plant sources as potential antiviral agents
Viral infections are considered as leading a health issue globally. Numerous numbers of biologically active anti-viral agents have been identified from plants and other organisms. Particularly, terpenoids are a major component of the plant secondary metabolites and a complexity of these structures is accompanied by the potency of their biological activities. It is believed that most of the terpenoids possess the bioactivity against viral infections and cancer diseases. Hence, affected by the pressing a need elevated by the spreading of seriously life-threaten viruses, this review highlights the importance of terpenoids and their activity as antiviral agents that can be employed to treat current lethal diseases such as HIV, H1N1, SARS-CoV and HSV
A review on triterpenoids from plant sources as potential antiviral agents
761-770Viral infections are considered as leading a health issue globally. Numerous numbers of biologically active anti-viral
agents have been identified from plants and other organisms. Particularly, terpenoids are a major component of the plant
secondary metabolites and a complexity of these structures is accompanied by the potency of their biological activities. It is
believed that most of the terpenoids possess the bioactivity against viral infections and cancer diseases. Hence, affected by
the pressing a need elevated by the spreading of seriously life-threaten viruses, this review highlights the importance of
terpenoids and their activity as antiviral agents that can be employed to treat current lethal diseases such as HIV, H1N1,
SARS-CoV and HSV
Design, Synthesis and Biological Studies of Tetrazole Fused olpidemimidazopyridines
New tetrazole fused imidazopyridine derivatives (12a–j) were developed to exploit their cytotoxic activity towards cancer cell lines-MCF7, A549, and MDA-MB-231, utilizing MTT reduction assay with doxorubicin as standard drug. The compounds 12 h and 12j demonstrated strong anticancer activity bearing IC50 values 1.44 µM and 1.33 µM against A549 cell line