SAFETY OF NEUROAXIAL BLOCKADES AT SURGICAL DELIVERY IN PATIENTS WITH DISSEMINATED SCLEROSIS

We realized, prospective study, including staging clinicolaboratory and specialized neurological research during 12 months after the operation, to estimate the course of disseminated, sclerosis after Cesarean section at the neuroaxial blockades with use of modern local anesthetics. We observed 17 patients of 26—30 years with disseminated, sclerosis. It is showed, that neuroaxial anesthesia techniques with modern local anesthetics at the operative delivery don't worsen the prognosis of underlying disease

Induced quantum numbers of a magnetic monopole at finite temperature

A Dirac electron field is quantized in the background of a Dirac magnetic monopole, and the phenomenon of induced quantum numbers in this system is analyzed. We show that, in addition to electric charge, also squares of orbital angular momentum, spin, and total angular momentum are induced. The functional dependence of these quantities on the temperature and the CP-violating vacuum angle is determined. Thermal quadratic fluctuations of charge and squared total angular momentum, as well as the correlation between them and their correlations with squared orbital angular momentum and squared spin, are examined. We find the conditions when charge and squared total angular momentum at zero temperature are sharp quantum observables rather than mere quantum averages.Comment: 24 pages, minor grammatical changes, journal versio

Morphological characteristics of zone of titanium nickelide mesh prosthesis implantation after esophagocardiopexy in experiment

The results of research using 20 rabbits are presented in the article. All animals underwent esophagocardiopexia by fixing nickel titanium mesh prosthesis to the diaphragm and the anterior wall of the stomach. The morphology of tissues in contact with the implant, histological and ultramicroscopic picture were assessed. Evaluation of foreign body reaction have demonstrated minimal degree of tissue reactions. After 6 weeks the changes of normal histological structure of the investigated organs were not detected. At the end of research period the collagen fibers formed the ordered structures around the metallic filaments. The obtained data have shown high biocompatibility of titanium nickelide mesh prosthesis and the low level of mesh-related complications

Results of the study of the immunogenic activity of cell envelopes of Francisella tularensis different subspicies (Report 2)

The effect of cell envelopes preparations of four subspecies of Francisella tularensis, derived from urea lysates of tularemia microbe on cytokine production by immunocompetent cells of experimental animals has been studied. Stimulating influence of F. tularensis cell envelopes preparations on cytokine synthesis on the 7th day after inoculation was shown. The results showed that the cell envelopes of different subspecies F. tularensis have different stimulatory effect on the production of proinflammatory cytokines and growth factors GM-CSF and G-CSF, further defining the immune system of host.The results allow to consider cell envelopes preparations of F. tularensis as constituent component in the development of subunit vaccines

Relative body mass index as a new tool for nutritional status assessment in children and adolescents with bronchial asthma

© 2017, Nizhny Novgorod State Medical Academy. All rights reserved.The aim of the investigation was to estimate the possibilities of using relative body mass index (RBMI) for determining age- and gender-specific aspects of nutritional status in children and adolescents with bronchial asthma (BA) of different severity degrees. Materials and Methods. The study involved 887 children and adolescents with BA of different severities, aged 5–17 years (61– 215 months), of them 655 were boys. Their body mass index (BMI) was evaluated based on the Z-score criterion and nutritional status was determined as recommended by the World Health Organization (WHO). To unify nutritional status assessment in patients of different age and gender groups, there was introduced RBMI representing the ratio of the patient’s BMI to gender- and age-specific median BMI value presented in the WHO reference data. Results. Nutritional status and its relation to BA were studied in children and adolescents using two parameters: the standard nutritional status indicator based on BMI Z-scores as recommended by WHO, and a new parameter, RBMI, representing the ratio of the patient’s BMI to gender- and age-specific median BMI value recommended by WHO. No significant nutritional status differences were found in the studied sample of patients with various degrees of BA severity. There was revealed a tendency to a decrease in the proportion of children with normal body weight and an increase in the proportion of overweight children as BA severity increased, χ2=26.82; р=0.08. Conclusion. Using RBMI for assessment of BA patients makes it possible to significantly facilitate clinical data analysis and obtain new data unavailable when standard parameters are applied

Применение удобрений пролонгированного действия при выращивании рассады земляники садовой

Timeliness. Currently, the Russian Federation has a high demand in healthy planting material of garden strawberries. The benefits of using fertilizers when growing strawberry seedlings have been proven by numerous studies. However, a comparative study of the effect of new fertilizers and methods of their application is very limited. In this regard, studies aimed at identifying the effectiveness of the use of prolonged-acting fertilizers in the production of garden strawberry planting material in protected soil conditions are relevant.Methods. Adapted to non-sterile conditions, ex vitro healthy garden strawberry plants were planted in a peat substrate of Veltorf LLC (recipe No. 5c/2) with the addition of Pg mix starter fertilizer with the structure NPK 14-16-18 + microelements (1.5 g/l of substrate). At the same time, prolonged-acting fertilizers were introduced into the substrate in the recommended concentrations: FertiPro Gran 1M (1.25 g/l of substrate), Ruscote 5-6M (3.0 g/l of substrate), Basacote Plus 6M (4.0 g/l of substrate), control peat substrate without fertilizers, PG mix standard.Results. It has been established that for the Karmen crop with an average runner-forming ability, the effectiveness of applying FertiPro Gran 1M fertilizer to the substrate was revealed, with the use of which, on the 180th day of cultivation, the number of runners and rosettes increases by 3.5–3.8 times compared to the control. At the same time, the yield of marketable seedlings is 95% compared to 70% in the control. For the Jūnija smaids crop with a high vine-forming ability, the effectiveness of all experimental variants with the application of FertiPro Gran 1M, Ruscote and Basacote Plus fertilizers to the substrate was revealed, with the use of which, on the 180th day of cultivation, the number of runners and rosettes increases by 1,9-2,5 times compared to the control. At the same time, the yield of marketable seedlings is 94-96% compared to 65% in the control.Conclusion. The introduction of long–acting fertilizers FertiPro Gran, Ruscote and Basacote Plus into the peat substrate with the addition of Pg mix starter fertilizer allowed a 2.3 – 3.8-fold increase in the number of runners obtained and 1.9-3.5-fold increase in the number of sockets obtained compared to the control without fertilizers. Актуальность. В настоящее время в Российской Федерации существует высокая потребность в оздоровленном посадочном материале земляники садовой. Преимущество применения удобрений при выращивании рассады земляники были доказаны многочисленными исследованиями. Однако сравнительное изучение действия влияния новых удобрений и методов их применения очень ограничено. В связи с этим, исследования направленные на выявление эффективности использования удобрений пролонгированного действия при производстве посадочного материала земляники садовой в условиях защищенного грунта являются актуальными.Методы. Адаптированные к нестерильным условиям оздоровленные еx vitro растения земляники садовой высаживали в торфяной субстрат компании ООО Велторф (рецепт № 5с/2) с добавлением стартового удобрения Pg mix со структурой NPK 14-16- 18 – микроэлементы (1,5 г/л субстрата). При этом в состав субстрата вводили удобрения пролонгированного действия в рекомендованных концентрациях FertiPro Gran 1М (1,25 г/л субстрата), Ruscote 5-6М (3,0 г/л субстрата), Basacote Plus 6М (4,0 г/л субстрата), контроль торфяной субстрат без удобрений, эталон PG mix.Результаты. Установлено, что для сорта Karmen со средней усообразовательной способностью выявлена эффективность внесения в субстрат удобрения FertiPro Gran 1М, при применении которого на 180 сутки выращивания в 3,5-3,8 раз увеличивается количество усов и розеток по сравнению с контролем и при этом выход товарной рассады составляет 95 % по сравнению с 70% в контроле. Для сорта Jūnija smaids с высокой усообразовательной способностью выявлена эффективность всех опытных вариантов с внесением в субстрат удобрений FertiPro Gran 1М, Ruscote и Basacote Plus при применении которых на 180 сутки выращивания в 1,9-2,5 раза увеличивается количество усов и розеток по сравнению с контролем и при этом выход товарной рассады составляет 94-96% по сравнению с 65% в контроле.Заключение. Внесение удобрений пролонгированного действия FertiPro Gran, Ruscote и Basacote Plus в торфяной субстрат с добавлением стартового удобрения Pg mix позволило 2,3-3,8 раз увеличить количество полученных усов и в 1,9- 3,5 раз полученных розеток по сравнению с контролем без удобрений.

Quaternary Selenides EuLnCuSe3: Synthesis, Structures, Properties and In Silico Studies

In this work, we report on the synthesis, in-depth crystal structure studies as well as optical and magnetic properties of newly synthesized heterometallic quaternary selenides of the Eu+2Ln+3Cu+1Se3 composition. Crystal structures of the obtained compounds were refined by the derivative difference minimization (DDM) method from the powder X-ray diffraction data. The structures are found to belong to orthorhombic space groups Pnma (structure type Ba2MnS3 for EuLaCuSe3 and structure type Eu2CuS3 for EuLnCuSe3, where Ln = Sm, Gd, Tb, Dy, Ho and Y) and Cmcm (structure type KZrCuS3 for EuLnCuSe3, where Ln = Tm, Yb and Lu). Space groups Pnma and Cmcm were delimited based on the tolerance factor t’, and vibrational spectroscopy additionally confirmed the formation of three structural types. With a decrease in the ionic radius of Ln3+ in the reported structures, the distortion of the (LnCuSe3) layers decreases, and a gradual formation of the more symmetric structure occurs in the sequence Ba2MnS3 → Eu2CuS3 → KZrCuS3. According to magnetic studies, compounds EuLnCuSe3 (Ln = Tb, Dy, Ho and Tm) each exhibit ferrimagnetic properties with transition temperatures ranging from 4.7 to 6.3 K. A negative magnetization effect is observed for compound EuHoCuSe3 at temperatures below 4.8 K. The magnetic properties of the discussed selenides and isostructural sulfides were compared. The direct optical band gaps for EuLnCuSe3, subtracted from the corresponding diffuse reflectance spectra, were found to be 1.87– 2.09 eV. Deviation between experimental and calculated band gaps is ascribed to lower d states of Eu2+ in the crystal field of EuLnCuSe3, while anomalous narrowing of the band gap of EuYbCuSe3 is explained by the low-lying charge-transfer state. Ab initio calculations of the crystal structures, elastic properties and phonon spectra of the reported compounds were performed. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.Funding: The research was supported by the Tyumen region within the framework of the grant agreement in the form of a grant to non-profit organizations no. 89-don dated 07.12.2020. This study was supported by the Ministry of Science and Higher Education of the Russian Federation (project no. FEUZ-2020-0054). This work was supported by state assignment of the Ministry of Science and Higher Education of the Russian Federation (Project Reg. No. 720000Ф.99.1.БЗ85АА13000). The work was conducted within the framework of the budget project № 0287-2021-0013 for the Institute of Chemistry and Chemical Technology SB RAS