Efficient collinear third-harmonic generation in a single two-dimensional nonlinear photonic crystal

We propose novel multi-phase-matched process that starts with generation of a pair of symmetric second-harmonic waves. Each of them interacts again with the fundamental wave to produce two constructively interfering third harmonic waves collinear to the fundamental input wave.Comment: Summary of presentation at the IQEC/LAT-2002 conferenc

Monitoring ultrashort pulses by transverse frequency doubling of counterpropagating pulses in random media

The authors study experimentally the transverse second-harmonic generation of counterpropagating pulses by a quasi-phase-matching in a medium with a random ferroelectric domain structure. The authors show that this parametric process results in a direct realization of the cross correlation of two optical signals and, therefore, it can be employed for direct characterizations of ultrashort pulses including their temporal structure and pulse front tilt.The authors acknowledge the support of the Australian Research Council

Generation of the second-harmonic Bessel beams via nonlinear Bragg diffraction

We generate conical second-harmonic radiation by transverse excitation of a two-dimensional annular periodically-poled nonlinear photonic structure with a fundamental Gaussian beam. We show that these conical waves are the far-field images of the Bessel beams generated in a crystal by parametric frequency conversion assisted by nonlinear Bragg diffraction.Comment: 4 pages, 5 figures. submitte

Nonlinear diffraction from a virtual beam

We observe experimentally a novel type of nonlinear diffraction in the process of two-wave mixing on a nonlinear quadratic grating. We demonstrate that when the nonlinear grating is illuminated simultaneously by two noncollinear beams, a second-harmonic diffraction pattern is generated by a virtual beam propagating along the bisector of the two pump beams. The observed diffraction phenomena is a purely nonlinear effect that has no analogue in linear diffraction

Multi-component optical solitary waves

We discuss several novel types of multi-component (temporal and spatial) envelope solitary waves that appear in fiber and waveguide nonlinear optics. In particular, we describe multi-channel solitary waves in bit-parallel-wavelength fiber transmission systems for high performance computer networks, multi-colour parametric spatial solitary waves due to cascaded nonlinearities of quadratic materials, and quasiperiodic envelope solitons due to quasi-phase-matching in Fibonacci optical superlattices.Comment: 12 pages, 11 figures; To be published in: Proceedings of the Dynamics Days Asia-Pacific: First International Conference on Nonlinear Science (Hong-Kong, 13-16 July, 1999), Editor: Bambi Hu (Elsevier Publishers, 2000

Positional Cloning of “Lisch-like”, a Candidate Modifier of Susceptibility to Type 2 Diabetes in Mice

In 404 Lepob/ob F2 progeny of a C57BL/6J (B6) x DBA/2J (DBA) intercross, we mapped a DBA-related quantitative trait locus (QTL) to distal Chr1 at 169.6 Mb, centered about D1Mit110, for diabetes-related phenotypes that included blood glucose, HbA1c, and pancreatic islet histology. The interval was refined to 1.8 Mb in a series of B6.DBA congenic/subcongenic lines also segregating for Lepob. The phenotypes of B6.DBA congenic mice include reduced β-cell replication rates accompanied by reduced β-cell mass, reduced insulin/glucose ratio in blood, reduced glucose tolerance, and persistent mild hypoinsulinemic hyperglycemia. Nucleotide sequence and expression analysis of 14 genes in this interval identified a predicted gene that we have designated “Lisch-like” (Ll) as the most likely candidate. The gene spans 62.7 kb on Chr1qH2.3, encoding a 10-exon, 646–amino acid polypeptide, homologous to Lsr on Chr7qB1 and to Ildr1 on Chr16qB3. The largest isoform of Ll is predicted to be a transmembrane molecule with an immunoglobulin-like extracellular domain and a serine/threonine-rich intracellular domain that contains a 14-3-3 binding domain. Morpholino knockdown of the zebrafish paralog of Ll resulted in a generalized delay in endodermal development in the gut region and dispersion of insulin-positive cells. Mice segregating for an ENU-induced null allele of Ll have phenotypes comparable to the B.D congenic lines. The human ortholog, C1orf32, is in the middle of a 30-Mb region of Chr1q23-25 that has been repeatedly associated with type 2 diabetes

Phase matching in nonlinear c(2) photonic crystals

We analyze harmonic generation in a two-dimensional (2D) χ(2) photonic crystal and demonstrate the possibility of multiple phase matching and multicolor parametric frequency conversion. We suggest a new type of photonic structure to achieve simultaneou