COVID-19患者との接触が精神科病院職員に与えた影響

博士（医学）・乙第1515号・令和3年12月21日© 2020 The Authors Psychiatry and Clinical Neurosciences.© 2020 Japanese Society of Psychiatry and Neurology.This is the peer reviewed version of the following article: [https://onlinelibrary.wiley.com/doi/10.1111/pcn.13179], which has been published in final form at [https://doi.org/10.1111/pcn.13179]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited

constructive comments and advice.

For this dissertation, I am extremely fortunate to have worked with my research supervisor Professor Mitsuru Ishizuka. He is a great supervisor and provided me with constant encouragement and guidance. His willingness to show me the clear research direction so that I could excel in my work was always inspiring. In the regular lab meetings, the fruitful and valuable ideas gained from the lab members on complementing this research are highly appreciated. The encouraging discussion was always the best way in reaching an optima solution for system flaw and the sources of fun as well. I would like to take this chance to send my greatest respect to Professor Hitoshi Iba, Hiroshi Dohi Sensei, Fujita Tameko san and Dr. Helmut Prendinger for helping me up throughout the years. Also, my highest gratitude to all my seniors, Dr. Yasufumi Takama, Dr. Santi Saeyor, Dr. Itsur

Carbonate record of temporal change in oxygen fugacity and gaseous species in asteroid Ryugu

The Hayabusa2 spacecraft explored asteroid Ryugu and brought its surface materials to Earth. Ryugu samples resemble Ivuna-type (CI) chondrites-the most chemically primitive meteorites-and contain secondary phyllosilicates and carbonates, which are indicative of aqueous alteration. Understanding the conditions (such as temperature, redox state and fluid composition) during aqueous alteration is crucial to elucidating how Ryugu evolved to its present state, but little is known about the temporal changes in these conditions. Here we show that calcium carbonate (calcite) grains in Ryugu and Ivuna samples have variable O-18/O-16 and C-13/C-12 ratios that are, respectively, 24-46 & PTSTHOUSND; and 65-108 & PTSTHOUSND; greater than terrestrial standard values, whereas those of calcium-magnesium carbonate (dolomite) grains are much more homogeneous, ranging within 31-36 & PTSTHOUSND; for oxygen and 67-75 & PTSTHOUSND; for carbon. We infer that the calcite precipitated first over a wide range of temperatures and oxygen partial pressures, and that the proportion of gaseous CO2/CO/CH4 molecules changed temporally. By contrast, the dolomite formed later in a more oxygen-rich and thus CO2-dominated environment when the system was approaching equilibrium. The characteristic isotopic compositions of secondary carbonates in Ryugu and Ivuna are not observed for other hydrous meteorites, suggesting a unique evolutionary pathway for their parent asteroid(s). The asteroid Ryugu experienced aqueous alteration under changing temperature and redox conditions, according to an isotopic analysis of secondary calcite and dolomite grains in samples from Ryugu obtained by the Hayabusa2 spacecraft