40 research outputs found
Corinne Pierreville (Ă©d. et comm.), Anthologie de la littĂ©rature Ă©rotique du Moyen Ăge
Lâanthologie conçue par Corinne Pierreville correspond Ă un dessein bien prĂ©cis, celui de donner lâimage la plus riche et la plus adĂ©quate de la littĂ©rature Ă©rotique mĂ©diĂ©vale. Lâa. propose donc un choix de textes qui permet de se faire une idĂ©e sur la relation que les gens du Moyen Ăge entretenaient avec leur corps et sur leurs fantasmes. Elle sâattache Ă montrer que certaines Ćuvres de lâĂ©poque mĂ©diĂ©vale sont plus novatrices dans le domaine Ă©rotique quâon ne le croit habituellement ; quâen ..
Histoires des Bretagnes 5. En marge, dir. HélÚne Bouget et Magali Coumert, Brest, Université de Bretagne Occidentale, 2015.
Le cinquiĂšme volume dâĂ©tudes consacrĂ©es aux Bretagnes mĂ©diĂ©vales a pour thĂšme principal la marginalitĂ©, notion dont les diffĂ©rents aspects (spatial, social, culturel) suscitent depuis un certain temps un foisonnement de recherches et que la situation gĂ©ographique des rĂ©gions celtiques rend incontournable lorsquâon se propose dâexplorer leur spĂ©cificitĂ©. Comme lâexpliquent les directrices du recueil dans lâintroduction, ce thĂšme fait Ă©cho Ă lâimage romantique des terres celtiques comme isolĂ©es..
Chaire, chair et bonne chĂšre. En hommage Ă Paul Bretel
Le titre du volume dâarticles dĂ©diĂ©s Ă Paul Bretel promet des lectures aussi utiles quâagrĂ©ables. Effectivement, outre les goĂ»ts et les dons culinaires de Paul Bretelsur lesquels reviennent plusieurs auteurs, on y apprend beaucoup. Comme lâexpliquent les Ă©diteurs, « lâopposition que souligne lâintitulĂ© de lâouvrage, entre le thĂšme religieux et Ă©difiant dâune part, et lâinspiration paĂŻenne (voir paillarde) et mondaine dâautre part, rend bien compte des aspects contrastĂ©s de la littĂ©rature et d..
Cloches et horloges dans les textes médiévaux
Le recueil fait suite Ă trois autres, consacrĂ©s Ă des objets que lâon peut considĂ©rer comme emblĂ©matiques pour un certain nombre de textes mĂ©diĂ©vaux, tous parus sous la direction de Fabienne Pomel aux Presses Universitaires de Rennes : Miroirs et jeux de miroirs dans la littĂ©rature mĂ©diĂ©vale, 2003 ; Les clefs des textes mĂ©diĂ©vaux : pouvoir, savoir et interprĂ©tation, 2006 et Cornes et plumes dans la littĂ©rature mĂ©diĂ©vale. Attributs, signes et emblĂšmes, 2010. Le sous-titre « Mesurer et maĂźtris..
Pluralité des points de vue dans la matiÚre tristanienne, Multiplicity of views on the matter of Tristan
Literary versions of the legend of Tristan and Isolde are suitable especially for an analysis of the issues connected with the point of view, particularly if it is understood in the literal, visual meaning, which is here closely associated with the narratological meaning. Lovers are constantly hiding, being followed, then found in the farthest recesses and exposed to gaze of the others, hostile or sympathetic. These gazes decide about their fate; a gaze is therefore an instrument of power, control, and judgment. In the first place, though, a gaze is the instrument of understanding and interpretation, which in many scenes are both shown as complex, problematic and non-obvious. Therefore, the opposition between favorable and hostile gazes is not always so strong: especially the gaze of King Mark, torn between the contradictory feelings for his wife and nephew, is characterized by ambivalence. This ambivalence can also be discerned in the changeable attitudes of some characters, hesitations of narrators and in numerous variants of particular versions of the legend.Literary versions of the legend of Tristan and Isolde are suitable especially for an analysis of the issues connected with the point of view, particularly if it is understood in the literal, visual meaning, which is here closely associated with the narratological meaning. Lovers are constantly hiding, being followed, then found in the farthest recesses and exposed to gaze of the others, hostile or sympathetic. These gazes decide about their fate; a gaze is therefore an instrument of power, control, and judgment. In the first place, though, a gaze is the instrument of understanding and interpretation, which in many scenes are both shown as complex, problematic and non-obvious. Therefore, the opposition between favorable and hostile gazes is not always so strong: especially the gaze of King Mark, torn between the contradictory feelings for his wife and nephew, is characterized by ambivalence. This ambivalence can also be discerned in the changeable attitudes of some characters, hesitations of narrators and in numerous variants of particular versions of the legend
Dâailes et dâoiseaux au Moyen Ăge. Langue, littĂ©rature, histoire des sciences
Pour pĂ©nĂ©trer le monde des oiseaux, il faut retrouver des yeux dâenfant, nous prĂ©vient Claude Thomasset dans lâintroduction de lâouvrage quâil a consacrĂ© Ă la mĂ©moire de Claude Gaignebet (p. 11). Le Moyen Ăge est peut-ĂȘtre pour la culture europĂ©enne cette enfance qui sâentend si bien avec le monde aviaire, tellement, Ă lâen croire le recueil en question, les oiseaux y Ă©taient prĂ©sents. Le recueil est divisĂ©, dâune façon un peu arbitraire, en cinq parties : « Dâailes et de mythes, dans les civ..
The concept of unstable atherosclerotic plaque and pharmacological therapeutic strategies
GĆĂłwnÄ
przyczynÄ
umieralnoĆci w Polsce sÄ
choroby ukĆadu sercowo-naczyniowego. W patogenezie miaĆŒdĆŒycy poczÄ
tkiem sÄ
zaburzenia funkcji ĆrĂłdbĆonka naczyniowego. MiaĆŒdĆŒyca jako proces zapalny, obejmujÄ
cy ĆcianÄ naczynia, rozwija siÄ poprzez wiele szlakĂłw sygnaĆowych. Zaburzenia gospodarki lipidowej dodatkowo przyspieszajÄ
jej rozwĂłj. RĂłwnieĆŒ zaburzenia przepĆywu krwi, definiowane jako maĆe i oscylacyjne naprÄĆŒenia ĆcinajÄ
ce, wpĆywajÄ
przez proces mechanotransdukcji na zwiÄkszenie ekspresji genĂłw odpowiedzialnych za odkĆadanie siÄ zĆogĂłw w Ćcianie naczyĆ. W konsekwencji dochodzi do nasilenia reakcji wolnorodnikowych. Nadal jednak brak jednoznacznych informacji na temat mechanizmĂłw progresji od zmian bezobjawowych do blaszek niestabilnych o wysokim ryzyku pÄkniÄcia. BiorÄ
c pod uwagÄ tak wiele mechanizmĂłw uczestniczÄ
cych w patogenezie rozwoju miaĆŒdĆŒycy dysponujemy juĆŒ wieloma farmakologicznymi strategiami zapobiegania i leczenia jej powikĆaĆ. W niniejszym artykule omĂłwiono gĆĂłwne grupy lekĂłw o udokumentowanej skutecznoĆci w stabilizacji blaszki miaĆŒdĆŒycowej. PojawiajÄ
siÄ nowe moĆŒliwoĆci jakie dajÄ
nanoleki, ktĂłre poprzez potencjalne zwiÄkszenie efektywnoĆci terapii jednoczeĆnie minimalizujÄ
jej powikĆania, dziaĆajÄ
c bezpoĆrednio w miejscu docelowym.The main cause of mortality in Poland are diseases of the cardiovascular system. Vascular endothelial dysfunction is the beginning of atherosclerosis development. Atherosclerosis, as an inflammatory process involving the vessel wall, evolves through multiple signaling pathways. While the dyslipidemia accelerate its development. Also, blood flow disorders defined as small and oscillating shear stress through the process of mechanotransduction, increases expression of genes, which are responsible for accumulating deposits in vessel walls. Consequently potentiates free radical reactions. There is still lack of clarity about mechanisms of progression from asymptomatic lesions to unstable plaques with high risk of rapture. Considering so many mechanisms participating in the pathogenesis of atherosclerosis we already have a lot of pharmacological strategies for preventing and treating its complications. This article discusses the main groups of drugs with documented effectiveness in the stabilization of atherosclerotic plaque. There are new opportunities offered by nanodrugs due to an effectiveness increase of the treatment while minimizing its complications by acting directly at the target site
The prognostic impact of therapeutic hypothermia after a sudden cardiac arrest in the course of myocardial infarction
Background: Mild therapeutic hypothermia (MTH) is one of the treatment methods recommended in post-sudden cardiac arrest (SCA) patients who remain unconscious after cardiopulmonary resuscitation. The present study aimed at assessing the prognostic impact of intravascular MTH on invasively treated patients with an acute myocardial infarction complicated by SCA.
Methods: The presented data were collected via a single-center retrospective analysis of the hospitalization and follow-up of 54 patients with post-myocardial infarction complicated by SCA. The patients were treated in the years 2014â2020 and the average follow-up period was 1141 ± 163 days. The population was divided into two groups: 28 patients treated with MTH (a therapeutic hypothermia [TH] group) and 26 patients treated without MTH (a non-TH group).
Results: The results indicate a trend toward improved in-hospital prognosis in the TH group, but the differences did not reach statistical significance: TH 25.0% vs. non-TH 34.5%, p = 0.554. An additional analysis of younger patients (under 60 years of age) revealed no significant differences between the TH and non-TH subgroups concerning in-hospital survival (in-hospital mortality rate: TH 6.7% vs. non-TH 30.0%, p = 0.267). Still, TH patients aged < 60 achieved a significantly better rate of follow-up survival (p = 0.041). The older (â„ 60) patient group showed no in-hospital mortality rate differences (TH 46.2% vs. non-TH 37.5%, p = 0.638). However, in-hospital bleeding frequency was significantly higher in patients aged â„ 60 from the hypothermia group (TH 50.0% vs. non-TH 6.7%, p = 0.011).
Conclusions: Intravascular MTH may improve the follow-up prognosis in patients aged < 60 with SCA in the early phase of myocardial infarction