13,538 research outputs found
Search for Spin-Dependent Short-Range Force Using Optically Polarized He Gas
We propose a new method to detect short-range \textit{P-} and \textit{T-}
violating interactions between nucleons, based on measuring the precession
frequency shift of polarized He nuclei in the presence of an unpolarized
mass. To maximize the sensitivity, a high-pressure He cell with thin glass
windows (250 ) is used to minimize the distance between the mass and
He. The magnetic field fluctuation is suppressed by using the He gas in
a different region of the cell as a magnetometer. Systematic uncertainties from
the magnetic properties of the mass are suppressed by flipping both the
magnetic field and spin directions. Without any magnetic shielding, our result
has already reached the sensitivity of the current best limit. With improvement
in uniformity and stability of the field, we can further improve the
sensitivity by two orders of magnitude over the force range from
m
Barrier Lowering and Field Penetration at Metal-Dielectric Interfaces
We report here photoemission measurements on
Si-SiO_2-Al structures in which the metal-SiO_2
barrier energy has been determined as a function
of the electric field strength E in the dielectric. The
expected barrier lowering is the sum of two terms:
a) the Schottky term, proportional to E^(1/2) and b)
a term due to the penetration of the electric field
into the metal electrode, proportional to E. The
experimental results are in good agreement with
the model, where the Schottky effect involves the
optical value of the dielectric constant of the oxide
and the Thomas-Fermi screening distance in the
metal is 1 Å. To our knowledge this represents the
first unambiguous quantitative determination of either effect in a polar dielectric, although the
Schottky effect alone has been observed in silicon
Performance of an Operating High Energy Physics Data Grid: D0SAR-Grid
The D0 experiment at Fermilab's Tevatron will record several petabytes of
data over the next five years in pursuing the goals of understanding nature and
searching for the origin of mass. Computing resources required to analyze these
data far exceed capabilities of any one institution. Moreover, the widely
scattered geographical distribution of D0 collaborators poses further serious
difficulties for optimal use of human and computing resources. These
difficulties will exacerbate in future high energy physics experiments, like
the LHC. The computing grid has long been recognized as a solution to these
problems. This technology is being made a more immediate reality to end users
in D0 by developing a grid in the D0 Southern Analysis Region (D0SAR),
D0SAR-Grid, using all available resources within it and a home-grown local task
manager, McFarm. We will present the architecture in which the D0SAR-Grid is
implemented, the use of technology and the functionality of the grid, and the
experience from operating the grid in simulation, reprocessing and data
analyses for a currently running HEP experiment.Comment: 3 pages, no figures, conference proceedings of DPF04 tal
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Evolution and chemical consequences of lightning-produced NOx observed in the North Atlantic upper troposphere
Airborne observations of NO during the Subsonics Assessment Ozone and Nitrogen Oxides Experiment (SONEX) reveal episodes of high NOx in the upper troposphere believed to be associated with lightning. Linkage to specific periods of lightning activity is possible through back trajectories and data from the National Lightning Detection Network. Lagrangian model calculations are used to explore the evolution of these high NOx plumes over the 1-2 days between their introduction and subsequent sampling by NASA's DC-8 aircraft. Simulations include expected changes in HNO3, H2O2, CH3OOH, HO2, and OH. Depending on the time of injection and dilution rate, initial NOx concentrations are estimated to range from 1 to 7 ppbv. Similar to many previous studies, simulated HNO3 concentrations tend to be greater than observations. Several possible explanations for this difference are explored. H2O2 observations are shown to be consistent with removal in convective activity. While it is possible that upper tropospheric CH3OOH is enhanced by convection, simulations show such increases in CH3OOH can be short-lived (e.g., < 12 hours) with no perceptible trace remaining at the time of sampling. High NO levels further prevent elevated levels of CH3OOH from propagating into increases in H2O2. HO2 is suppressed through reaction with NO in all cases. Simulated increases in OH exceeded a factor of 2 for some cases, but for the highest NOx levels, loss of OH via OH+NO2 offset production from HO2+NO. Additional increases in OH of 30-60% could result from convection of CH3OOH. A final point of discussion concerns how the chemistry within these plumes, their long-range transport, and their potential importance in sustaining background NOx far from source regions present a challenge to global and regional model simulations. Copyright 2000 by the American Geophysical Union
Metabolism and growth inhibition of four retinoids in head and neck squamous normal and malignant cells
Isotretinoin (13- cis -retinoic acid, 13cRA) has proven to be active in chemoprevention of head and neck squamous cell carcinoma (HNSCC). Moreover, both all-trans-retinoic acid (ATRA) and 13cRA induce objective responses in oral premalignant lesions. After binding of retinoids to retinoic acid receptors (RARs and RXRs) dimers are formed that are able to regulate the expression of genes involved in growth and differentiation. We compared the metabolism and level of growth inhibition of 13cRA with that of ATRA, 9cRA and retinol in four HNSCC cell lines and normal oral keratinocyte cultures (OKC). These retinoid compounds are known to bind with different affinities to the retinoic acid receptors. We observed that all retinoids were similar with respect to their capacity to induce growth inhibition. One HNSCC line could be ranked as sensitive, one as moderately sensitive and the remaining two were totally insensitive; OKC were moderately sensitive. The rate at which the cells were able to catabolize the retinoid was similar for all compounds. Retinoid metabolism in HNSCC cells resulted in a profile of metabolites that was unique for each retinoid. These metabolic profiles were different in OKC. Our findings indicate that differences in retinoid receptor selectivity of these retinoids do not influence the level of growth inhibition and rate of metabolism. © 2001 Cancer Research Campaign http://www.bjcancer.co
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Airborne tunable diode laser measurements of formaldehyde during TRACE-P: Distributions and box model comparisons
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