5,068 research outputs found

    Solitary waves and their stability in colloidal media: semi-analytical solutions

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    Spatial solitary waves in colloidal suspensions of spherical dielectric nanoparticles are considered. The interaction of the nanoparticles is modelled as a hard-sphere gas, with the Carnahan-Starling formula used for the gas compressibility. Semi-analytical solutions, for both one and two spatial dimensions, are derived using an averaged Lagrangian and suitable trial functions for the solitary waves. Power versus propagation constant curves and neutral stability curves are obtained for both cases, which illustrate that multiple solution branches occur for both the one and two dimensional geometries. For the one-dimensional case it is found that three solution branches (with a bistable regime) occur, while for the two-dimensional case two solution branches (with a single stable branch) occur in the limit of low background packing fractions. For high background packing fractions the power versus propagation constant curves are monotonic and the solitary waves stable for all parameter values. Comparisons are made between the semi-analytical and numerical solutions, with excellent comparison obtained.Comment: Paper to appear in Dynamics of Continuous, Discrete and Impulsive Systems, Series

    Transcritical shallow-water flow past topography: finite-amplitude theory

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    We consider shallow-water flow past a broad bottom ridge, localized in the flow direction, using the framework of the forced SuGardner (SG) system of equations, with a primary focus on the transcritical regime when the Froude number of the oncoming flow is close to unity. These equations are an asymptotic long-wave approximation of the full Euler system, obtained without a simultaneous expansion in the wave amplitude, and hence are expected to be superior to the usual weakly nonlinear Boussinesq-type models in reproducing the quantitative features of fully nonlinear shallow-water flows. A combination of the local transcritical hydraulic solution over the localized topography, which produces upstream and downstream hydraulic jumps, and unsteady undular bore solutions describing the resolution of these hydraulic jumps, is used to describe various flow regimes depending on the combination of the topography height and the Froude number. We take advantage of the recently developed modulation theory of SG undular bores to derive the main parameters of transcritical fully nonlinear shallow-water flow, such as the leading solitary wave amplitudes for the upstream and downstream undular bores, the speeds of the undular bores edges and the drag force. Our results confirm that most of the features of the previously developed description in the framework of the unidirectional forced Kortewegde Vries (KdV) model hold up qualitatively for finite amplitude waves, while the quantitative description can be obtained in the framework of the bidirectional forced SG system. Our analytic solutions agree with numerical simulations of the forced SG equations within the range of applicability of these equations

    Human computer interaction for international development: past present and future

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    Recent years have seen a burgeoning interest in research into the use of information and communication technologies (ICTs) in the context of developing regions, particularly into how such ICTs might be appropriately designed to meet the unique user and infrastructural requirements that we encounter in these cross-cultural environments. This emerging field, known to some as HCI4D, is the product of a diverse set of origins. As such, it can often be difficult to navigate prior work, and/or to piece together a broad picture of what the field looks like as a whole. In this paper, we aim to contextualize HCI4D—to give it some historical background, to review its existing literature spanning a number of research traditions, to discuss some of its key issues arising from the work done so far, and to suggest some major research objectives for the future

    Staphylococcus aureus in cystic fibrosis: pivotal role or bit part actor?

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    Purpose of review: describe why this review is timely and relevant. The cystic fibrosis lung has long been appreciated as a competitive niche for complex interactions between bacterial species. The individual relationships between effects on the host, and thereafter clinical outcomes, has been poorly understood. We aim to describe the role of Staphyloccus aureus, one of the most commonly encountered bacteria cultured from the respiratory tracts of people with CF, and it’s complex interplay with other organisms, with particular attention to Pseudomonas aeruginosa. Recent findings: describe the main themes in the literature covered by the article. We describe the challenges posed in understanding the role that S. aureus plays in the CF lung, including the difficulties in interpreting culture results depending upon sampling technique, relationships with P. aeruginosa and the rest of the microbiome, as well as discussing the relative merits and potential harms of antibiotic prophylaxis. Finally, we describe the particular challenge of methicillin-resistant S. aureus. Summary: describe the implications of the findings for clinical practice or research. We describe research underway that will address the long-held contentious issues of antibiotic prophylaxis. We also describe the emerging research interest in determining whether, at differences phases in the evolution of CF airways infection, S. aureus infection can have both harmful and protective effects for the host

    Physical fitness and prior physical activity are both associated with less cortisol secretion during psychosocial stress

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    Background: Evidence linking fitness and decreased psychosocial stress comes from studies of athletes and typically relies upon self-report measures. Furthermore, there is little evidence regarding the impact of physical activity (PA) prior to a stressor. The aims of this study were to determine whether fitness and prior PA influence cortisol concentrations during psychosocial stress. Methods: Seventy-five non-athletic participants took part in a submaximal walk prior to the Trier Social Stress Test for Groups (TSST-G). During the walk, fitness was assessed using heart rate (HR). A further 89 participants took part in the TSST-G without the walk. Stress responsiveness was assessed using salivary cortisol collected at 10-min intervals on seven occasions. Results: Hierarchical multiple regression revealed that average walking HR accounted for 9% of the variance in cortisol secretion (P = .016), where a higher HR was associated with higher cortisol secretion. Between-subjects ANCOVA revealed that the walking group had a significantly lower cortisol secretion than the non-walking group (P = .009). Conclusions: These findings indicate that fitter individuals have reduced cortisol secretion during psychosocial stress. They also indicate that prior PA can reduce cortisol concentrations during psychosocial stress and are suggestive of a role of PA in reducing the impact of stress on health

    The effect of the visual exercise environment on the response to psychological stress: a pilot study

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    Background: Performing physical activity whilst exposed to nature can improve health. However, there is little evidence of its impact on stress outcomes. The aim of this study was to examine the influence of the visual exercise environment on the response to a psychosocial stressor. Methods: Eighteen participants were randomised to one of three conditions: i. control; ii. Nature or; iii. Built condition. Participants exercised for 30min on a treadmill at 50% of their VO2max whilst viewing a video of either a natural or built environment or a blank screen. Following the exercise, participants completed the Trier Social Stress Test (TSST), a standardised laboratory stressor. Salivary samples were collected before, during and after the TSST to calculate cortisol reactivity and recovery. Results: One-way ANOVA revealed a significant effect of viewing condition on cortisol reactivity [F (2, 11) = 4.686, p = .034; n2p= .460]; with significantly lower reactivity in the built compared to the nature condition (p = .027, d=1.73). There was no effect of condition on cortisol recovery (P>0.05; n2p= .257). Conclusions: In the context of the adverse health impact of lower (i.e. blunted) cortisol responding, these findings could indicate a negative impact of the built environment on stress responses

    Electrochemistry and application of a novel monosubstituted squarate electron-transfer mediator in a glucose oxidase-doped poly(phenol) sensor

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    Electrosynthetic poly(phenol) nanofilms were deposited in situ on platinum electrodes in the presence and absence of glucose oxidase. The synthesis charges and currents of the nonconducting polymer films were recorded at various applied potentials for films grown from 25–100 mM phenol concentrations. Film parameters such as the standard rate constant for film deposition, film thickness, and surface concentration of the poly(phenol) films were evaluated from the cyclic and step voltammograms of the polymerization process. A novel electron-transfer mediator consisting of monosubstituted 4-hydroxycyclobut-3-ene-1,2-dione (squarate) was used as a mediator for Pt/poly(phenol) nano-film/GOx amperometric glucose biosensors. Amperometric responses for 3-diphenylamino-4-hydroxycyclobut-3-ene-1,2- dione (diphenylaminosquarate: E°â€Č = of +328 mV/Ag-AgCl at pH 7.0)-mediated systems were measured by both steady-state amperometric and cyclic voltammetry. The sensor sensitivity was calculated to be 558 nA cm –2 (”M) –1

    A Quantitative Comparison of Opacities Calculated Using the Distorted- Wave and R\boldsymbol{R}-Matrix Methods

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    The present debate on the reliability of astrophysical opacities has reached a new climax with the recent measurements of Fe opacities on the Z-machine at the Sandia National Laboratory \citep{Bailey2015}. To understand the differences between theoretical results, on the one hand, and experiments on the other, as well as the differences among the various theoretical results, detailed comparisons are needed. Many ingredients are involved in the calculation of opacities; deconstructing the whole process and comparing the differences at each step are necessary to quantify their importance and impact on the final results. We present here such a comparison using the two main approaches to calculate the required atomic data, the RR-Matrix and distorted-wave methods, as well as sets of configurations and coupling schemes to quantify the effects on the opacities for the Fe XVIIFe\ XVII and Ni XIVNi\ XIV ions.Comment: 10 pages, 2 figure
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