Methodology for estimation of total body composition in laboratory mammals

A standardized dissection and chemical analysis procedure was developed for individual animals of several species in the size range mouse to monkey (15 g to 15 kg). The standardized procedure permits rigorous comparisons to be made both interspecifically and intraspecifically of organ weights and gross chemical composition in mammalian species series, and was applied successfully to laboratory mice, hamsters, rats, guinea pigs, and rabbits, as well as to macaque monkeys. The procedure is described in detail

Merit - An evaluation tool for 100% renewable energy provision

Islands represent an interesting challenge in terms of energy supply. A great deal of work has been carried out to look at specific aspects of this issue on different islands. Unfortunately, results from one study cannot be easily applied to other islands due to island-specific resources and energy-use profiles. A quantitative evaluation tool (MERIT) is presented here, which is able to match half-hourly energy demands (heat, electricity, hot water and transport) with local supplies. The program examines the energy balance on any scale, from an individual building through to an entire country, thereby providing a powerful and generic aid to decision making. This paper demonstrates the generality and usefulness of MERIT by using it to analyse the options for creating an energy-autonomous community on a typical, small island off the west coast of Scotland. Results are presented showing the feasibility of accomplishing 100% renewable provision on this island using available local resources

Discovery of short-period binary millisecond pulsars in four globular clusters

We report the discovery using the Parkes radio telescope of binary millisecond pulsars in four clusters for which no associated pulsars were previously known. The four pulsars have pulse periods lying between 3 and 6 ms. All are in circular orbits with low-mass companions and have orbital periods of a few days or less. One is in a 1.7-hour orbit with a companion of planetary mass. Another is eclipsed by a wind from its companion for 40% of the binary period despite being in a relatively wide orbit. These discoveries result from the use of improved technologies and prove that many millisecond pulsars remain to be found in globular clusters.Comment: 4 pages, 2 figs, 1 table - Accepted by Astrophysical Journal Letter

Light echoes reveal an unexpectedly cool Eta Carinae during its 19th-century Great Eruption

Eta Carinae (Eta Car) is one of the most massive binary stars in the Milky Way. It became the second-brightest star in the sky during its mid-19th century "Great Eruption," but then faded from view (with only naked-eye estimates of brightness). Its eruption is unique among known astronomical transients in that it exceeded the Eddington luminosity limit for 10 years. Because it is only 2.3 kpc away, spatially resolved studies of the nebula have constrained the ejected mass and velocity, indicating that in its 19th century eruption, Eta Car ejected more than 10 M_solar in an event that had 10% of the energy of a typical core-collapse supernova without destroying the star. Here we report the discovery of light echoes of Eta Carinae which appear to be from the 1838-1858 Great Eruption. Spectra of these light echoes show only absorption lines, which are blueshifted by -210 km/s, in good agreement with predicted expansion speeds. The light-echo spectra correlate best with those of G2-G5 supergiant spectra, which have effective temperatures of ~5000 K. In contrast to the class of extragalactic outbursts assumed to be analogs of Eta Car's Great Eruption, the effective temperature of its outburst is significantly cooler than allowed by standard opaque wind models. This indicates that other physical mechanisms like an energetic blast wave may have triggered and influenced the eruption.Comment: Accepted for publication by Nature; 4 pages, 4 figures, SI: 6 pages, 3 figures, 5 table

Mode Switching and Subpulse Drifting in PSR B0826-34

We present high-quality observations of PSR B0826-34 at 1374 MHz. The emission from this pulsar exhibits strong bursts of pulses followed by long periods of `null' pulses. When it is strong, the radiation extends through the whole pulse period. We show for the first time that there is weak emission during the `null' phases, which should therefore be considered to be a different mode rather than a null. During this weak mode the profile is similar to that observed in the strong mode at low radio frequency. Using a phase-tracking method, the pattern of drifting subpulses during the strong mode is seen to be coherent across the whole profile. The drift rate is variable and includes positive and negative values. Thirteen subpulse bands have been directly observed, covering the whole longitude range. The subpulses and their spacings ($P_2$) are wider in one half of the profile than those in the other half. This difference, and the variation of observed $P_2$ within the two regions, can be accounted for if the magnetic pole is inclined to the rotation axis by about 0.5 degrees. These two regions appear to represent radiation from outer and inner cones. The intensity modulation of subpulses in all longitude ranges is related to the magnitude of the drift rate.Comment: 8 pages, 10 figures. Accepted for publication in MNRA

Effects of the Cosmos 1129 Soviet paste diet on body composition in the growing rat

Six Simonsen albino rats (45 days of age) were placed on a regimen of 40 g/day the semipurified Soviet paste diet used in the 18.5 day Cosmos 1129 spacecraft was to support the rats for various experiments on the physiological effects of weightlessness. The animals were maintained on the Soviet paste diet for 35 days, metabolic rate was measured and body composition was determined by direct analysis. The results were compared with a control group of rates of the same age, which had been kept on a standard commercial grain diet during the same period of time

Spatial and temporal dynamics of malaria transmission in rural western Kenya

ABSTRACT: BACKGROUND: Understanding the impact of reducing Plasmodium falciparum malaria transmission requires estimates of the relationship between health outcomes and exposure to infectious mosquitoes. However, measures of exposure such as mosquito density and entomological inoculation rate (EIR) are generally aggregated over large areas and time periods, biasing the outcome-exposure relationship. There are few studies examining the extent and drivers of local variation in malaria exposure in endemic areas. METHODS: We describe the spatio-temporal dynamics of malaria transmission intensity measured by mosquito density and EIR in the KEMRI/CDC health and demographic surveillance system using entomological data collected during 2002-2004. Geostatistical zero inflated binomial and negative binomial models were applied to obtain location specific (house) estimates of sporozoite rates and mosquito densities respectively. Model-based predictions were multiplied to estimate the spatial pattern of annual entomological inoculation rate, a measure of the number of infective bites a person receive per unit of time. The models included environmental and climatic predictors extracted from satellite data, harmonic seasonal trends and parameters describing space-time correlation. RESULTS: Anopheles gambiae s.l was the main vector species accounting for 86% (n=2309) of the total collected mosquitoes with the remainder being Anopheles funestus. Sixty eight percent (757/1110) of the surveyed houses had no mosquitoes. Distance to water bodies, vegetation and day temperature were significantly associated with mosquito density. Overall annual point estimates of EIR were 6.7, 9.3 and 9.6 infectious bites per annum for 2002, 2003 and 2004 respectively. Monthly mosquito density and EIR varied over the study period peaking in May during the wet season. The predicted and observed densities and EIR showed a strong seasonal and spatial pattern over the study area. CONCLUSIONS: Spatio-temporal maps of malaria transmission intensity obtained in this study are not only useful in understanding variability in malaria epidemiology over small areas but also provides a high resolution exposure surface that can be used to analyse the impact of malaria exposure on mortalit

Optical spectroscopic observations of gamma-ray blazar candidates II. The 2013 KPNO campaign in the Northern Hemisphere

We recently started a systematic search of low-energy counterparts of the unidentified gamma-ray sources (UGSs) listed in the Fermi-Large Area Telescope (LAT) First Source Catalog (1FGL) and the Fermi-LAT 2-Year Source Catalog (2FGL).} The main goal of our investigation is to find active galaxies belonging to the blazar class that lie within the positional uncertainty region of the UGSs and thus could be their potential low-energy counterparts. To achieve our aims, we first adopted several procedures based on the peculiar observational properties of blazars in the radio and in the IR. Then we carried out a follow-up spectroscopic campaign in the optical band to verify the nature of the candidates selected as potential counterparts of the UGSs. Here we present the results of the observations carried out in 2013 in the Northern Hemisphere at Kitt Peak National Observatory (KPNO). Optical spectroscopy is crucial to confirm the nature of the sources and can be used to estimate their redshifts; it will also allow us to test the robustness of our methods when the whole campaign is completed. Here we present the optical spectroscopic observations of 39 sources. Within our sample we found that 6 sources are blazars, candidates to be low-energy counterparts of the UGSs listed in the 2FGL. We confirm that an additional 8 sources, previously classified as active galaxies of uncertain type and associated in the 2FGL, are also all BL Lac objects. Moreover, we also present 20 new spectra for known blazars listed in the Multi-frequency Catalogue of Blazars as having an uncertain redshift and/or being classified as BL Lac candidates. We conclude that our methods for selecting gamma-ray blazar candidates allows us to discover new blazars and increase the list of potential low-energy counterparts for the Fermi UGSs.Comment: 27 pages, 39 figures, 1 table, A&A accepted for publication (pre-proof version