Factors contributing to the time taken to consult with symptoms of lung cancer: a cross-sectional study

<b>Objectives</b>: To determine what factors are associated with the time people take to consult with symptoms of lung cancer, with a focus on those from rural and socially deprived areas. <b>Methods</b>: A cross-sectional quantitative interview survey was performed of 360 patients with newly diagnosed primary lung cancer in three Scottish hospitals (two in Glasgow, one in NE Scotland). Supplementary data were obtained from medical case notes. The main outcome measures were the number of days from (1) the date participant defined first symptom until date of presentation to a medical practitioner; and (2) the date of earliest symptom from a symptom checklist (derived from clinical guidelines) until date of presentation to a medical practitioner. <b>Results</b>: 179 participants (50%) had symptoms for more than 14 weeks before presenting to a medical practitioner (median 99 days; interquartile range 31–381). 270 participants (75%) had unrecognised symptoms of lung cancer. There were no significant differences in time taken to consult with symptoms of lung cancer between rural and/or deprived participants compared with urban and/or affluent participants. Factors independently associated with increased time before consulting about symptoms were living alone, a history of chronic obstructive pulmonary disease (COPD) and longer pack years of smoking. Haemoptysis, new onset of shortness of breath, cough and loss of appetite were significantly associated with earlier consulting, as were a history of chest infection and renal failure. <b>Conclusion</b>: For many people with lung cancer, regardless of location and socioeconomic status, the time between symptom onset and consultation was long enough to plausibly affect prognosis. Long-term smokers, those with COPD and/or those living alone are at particular risk of taking longer to consult with symptoms of lung cancer and practitioners should be alert to this

Nanoengineering Carbon Allotropes from Graphene

Monolithic structures can be built into graphene by the addition and subsequent re-arrangement of carbon atoms. To this end, ad-dimers of carbon are a particularly attractive building block because a number of emerging technologies offer the promise of precisely placing them on carbon surfaces. In concert with the more common Stone-Wales defect, repeating patterns can be introduced to create as yet unrealized materials. The idea of building such allotropes out of defects is new, and we demonstrate the technique by constructing two-dimensional carbon allotropes known as haeckelite. We then extend the idea to create a new class of membranic carbon allotropes that we call \emph{dimerite}, composed exclusively of ad-dimer defects.Comment: 5 pages, 5 figure

Effect of initial correlations on short-time decoherence

We study the effect of initial correlations on the short-time decoherence of a particle linearly coupled to a bath of harmonic oscillators. We analytically evaluate the attenuation coefficient of a Schroedinger cat state both for a free and a harmonically bound particle, with and without initial thermal correlations between the particle and the bath. While short-time decoherence appears to be independent of the system in the absence of initial correlations, we find on the contrary that, for initial thermal correlations, decoherence becomes system dependent even for times much shorter than the characteristic time of the system. The temperature behavior of this system dependence is discussed.Comment: 7 pages, 1 figur

Cut Vertices and Semi-Inclusive Deep Inelastic Processes

Cut vertices, a generalization of matrix elements of local operators, are revisited, and an expansion in terms of minimally subtracted cut vertices is formulated. An extension of the formalism to deal with semi-inclusive deep inelastic processes in the target fragmentation region is explicitly constructed. The problem of factorization is discussed in detail.Comment: LaTex2e, 24 pages including 17 postscript figure

Magnetoresistance of Two-Dimensional Fermions in a Random Magnetic Field

We perform a semiclassical calculation of the magnetoresistance of spinless two-dimensional fermions in a long-range correlated random magnetic field. In the regime relevant for the problem of the half filled Landau level the perturbative Born approximation fails and we develop a new method of solving the Boltzmann equation beyond the relaxation time approximation. In absence of interactions, electron density modulations, in-plane fields, and Fermi surface anisotropy we obtain a quadratic negative magnetoresistance in the weak field limit.Comment: 12 pages, Latex, no figures, Nordita repor

Three point SUSY Ward identities without Ghosts

We utilise a non-local gauge transform which renders the entire action of SUSY QED invariant and respects the SUSY algebra modulo the gauge-fixing condition, to derive two- and three-point ghost-free SUSY Ward identities in SUSY QED. We use the cluster decomposition principle to find the Green's function Ward identities and then takes linear combinations of the latter to derive identities for the proper functions.Comment: 20 pages, no figures, typos correcte

The Quark-Hadron Phase Transition, QCD Lattice Calculations and Inhomogeneous Big-Bang Nucleosynthesis

We review recent lattice QCD results for the surface tension at the finite temperature quark-hadron phase transition and discuss their implications on the possible scale of inhomogeneities. In the quenched approximation the average distance between nucleating centers is smaller than the diffusion length of a protron, so that inhomogeneities are washed out by the time nucleosynthesis sets in. Consequently the baryon density fluctuations formed by a QCD phase transition in the early universe cannot significantly affect standard big-bang nucleosynthesis calculations and certainly cannot allow baryons to close the universe. At present lattice results are inconclusive when dynamical fermions are included.Comment: 8 pages, LaTe

Electron energy loss and induced photon emission in photonic crystals

The interaction of a fast electron with a photonic crystal is investigated by solving the Maxwell equations exactly for the external field provided by the electron in the presence of the crystal. The energy loss is obtained from the retarding force exerted on the electron by the induced electric field. The features of the energy loss spectra are shown to be related to the photonic band structure of the crystal. Two different regimes are discussed: for small lattice constants $a$ relative to the wavelength of the associated electron excitations $\lambda$, an effective medium theory can be used to describe the material; however, for $a\sim\lambda$ the photonic band structure plays an important role. Special attention is paid to the frequency gap regions in the latter case.Comment: 12 pages, 7 figure