GreenCare for Children -- Measuring Environmental Hazards in the Childcare Industry

Presents findings from a two-year survey administered to a random sampling of childcare providers. Developed and interpreted by a diverse team of industry, technical, and educational experts

Suppression of spin-torque in current perpendicular to the plane spin-valves by addition of Dy cap layers

We demonstrate that the addition of Dy capping layers in current perpendicular to the plane giant magneto-resistive spin-valves can increase the critical current density beyond which spin-torque induced instabilities are observed by about a factor of three. Current densities as high as 5e7 A/cm2 are measured provided that the electron current flows from the free to the reference layer. While Dy capped samples exhibit nonmagnetic 1/f noise, it is sufficiently small to be unimportant for read head operation at practical data rates.Comment: 13 pages (manuscript form), with 5 figures. Submitted for publicatio

Thermal Effects on the Magnetic Field Dependence of Spin Transfer Induced Magnetization Reversal

We have developed a self-aligned, high-yield process to fabricate CPP (current perpendicular to the plane) magnetic sensors of sub 100 nm dimensions. A pinned synthetic antiferromagnet (SAF) is used as the reference layer which minimizes dipole coupling to the free layer and field induced rotation of the reference layer. We find that the critical currents for spin transfer induced magnetization reversal of the free layer vary dramatically with relatively small changes the in-plane magnetic field, in contrast to theoretical predictions based on stability analysis of the Gilbert equations of magnetization dynamics including Slonczewski-type spin-torque terms. The discrepancy is believed due to thermal fluctuations over the time scale of the measurements. Once thermal fluctuations are taken into account, we find good quantitative agreement between our experimental results and numerical simulations.Comment: 14 pages, 4 figures, Submitted to Appl. Phys. Lett., Comparison of some of these results with a model described by N. Smith in cond-mat/040648

Body representation difficulties in children and adolescents with autism may be due to delayed development of visuo-tactile temporal binding

Recent research suggests visuo-tactile binding is temporally extended in autism spectrum disorders (ASD), although it is not clear whether this specifically underlies altered body representation in this population. In the current study children and adolescents with ASD, and typically developing controls, placed their hand into mediated reality system (MIRAGE) and saw two identical live video images of their own right hand. One image was in the proprioceptively correct location (veridical hand) and the other was displaced to either side. While visuotactile feedback was applied via brushstroke to the participant’s (unseen) right finger, they viewed one hand image receiving synchronous brushstrokes and the other receiving brushstrokes with a temporal delay (60, 180 and 300ms). After brushing, both images disappeared from view and participants pointed to a target, with direction of movement indicating which hand was embodied. ASD participants, like younger mental aged-matched controls, showed reduced embodiment of the spatially incongruent, but temporally incongruent, hand compared to chronologically age-matched controls at shorter temporal delays. This suggests development of visuo-tactile integration may be delayed in ASD. Findings are discussed in relation to atypical body representation in ASD and how this may contribute to social and sensory difficulties within this population

Bacterial defences: mechanisms, evolution and antimicrobial resistance

Throughout their evolutionary history, bacteria have faced diverse threats from other microorganisms, including competing bacteria, bacteriophages and predators. In response to these threats, they have evolved sophisticated defence mechanisms that today also protect bacteria against antibiotics and other therapies. In this Review, we explore the protective strategies of bacteria, including the mechanisms, evolution and clinical implications of these ancient defences. We also review the countermeasures that attackers have evolved to overcome bacterial defences. We argue that understanding how bacteria defend themselves in nature is important for the development of new therapies and for minimizing resistance evolution

Measurement of Gilbert damping parameters in nanoscale CPP-GMR spin-valves

In-situ, device level measurement of thermal mag-noise spectral linewidths in 60nm diameter CPP-GMR spin-valve stacks of IrMn/ref/Cu/free, with reference and free layer of similar CoFe/CoFeGe alloy, are used to simultaneously determine the intrinsic Gilbert damping for both magnetic layers. It is shown that careful alignment at a "magic-angle" between free and reference layer static equilibrium magnetization can allow direct measurement of the broadband intrinsic thermal spectra in the virtual absence of spin-torque effects which otherwise grossly distort the spectral line shapes and require linewidth extrapolations to zero current (which are nonetheless also shown to agree well with the direct method). The experimental magic-angle spectra are shown to be in good qualitative and quantitative agreement with both macrospin calculations and micromagnetic eigenmode analysis. Despite similar composition and thickness, it is repeatedly found that the IrMn exchange pinned reference layer has ten times larger intrinsic Gilbert damping (alpha ~ 0.1) than that of the free-layer (alpha ~ 0.01). It is argued that the large reference layer damping results from strong, off -resonant coupling to to lossy modes of an IrMn/ref couple, rather than commonly invoked two-magnon processes.Comment: 11 pages (2-column format), 12 figures. This work was presented at the 2010 Joint MMM-Intermag Conference (Washington, DC) as paper AB-01 (invited

Treatment and outcomes for synovial sarcoma patients in Western Australia: the role of neoadjuvant chemoradiotherapy

Background This is a retrospective review of synovial sarcoma (SS) patients treated over the last 12 years in Western Australia (WA). SS is both chemo and radiotherapy sensitive. Results of trials in adjuvant chemotherapy are conflicting and there is limited support for neoadjuvant chemotherapy. The use of combined chemoradiotherapy is based on institutional preferences. Aim We reviewed the outcomes for SS patients treated in WA over a 12 year period focusing on patients who received neoadjuvant chemoradiotherapy (NACRT). Methods Patient details including demographics, histopathology, treatment details, were obtained from the WA sarcoma database (2006-2018). Progression free survival (PFS) and overall survival (OS) were derived for whole cohort. Results Twenty seven patients were identified with SS with equal gender incidence. Median age of the cohort was 36 (14-76) years. The most common primary site of disease was extremity (81.5%). 22/27 patients presented with only localized disease and 59.2% of these received neo-adjuvant treatment. Of those who received neoadjuvant treatment, 56.2% had NACRT, while 25.0% and 18.7% of patients had chemotherapy and radiotherapy respectively. Mesna, doxorubicin, ifosfamide, dacarbazine (MAID) was the most commonly used chemotherapy regimen as neoadjuvant or adjuvant treatment while ifosfamide (93.7%) was the most commonly used chemotherapy drug in any setting. There was no reported case of disease progression in group of patients who received NACRT apart from one patient who had oligometastatic disease at diagnosis. Median OS of the whole cohort was 38 months while median PFS was 24 months. Bone marrow toxicity was the most commonly reported high grade toxicity in NACRT group (55.5%) but there were no treatment related deaths. Conclusion NACRT is not widely adopted and treatment is based on institutional preferences, however our data shows that NACRT is a feasible therapy option. NACRT should be evaluated prospectively in a randomized trial