11,567 research outputs found
Simple Models for Turbulent Self-Regulation in Galaxy Disks
We propose that turbulent heating, wave pressure and gas exchanges between
different regions of disks play a dominant role in determining the preferred,
quasi-equilibrium, self-similar states of gas disks on large-scales. We present
simple families of analytic, thermohydrodynamic models for these global states,
which include terms for turbulent pressure and Reynolds stresses. Star
formation rates, phase balances, and hydrodynamic forces are all tightly
coupled and balanced. The models have stratified radial flows, with the cold
gas slowly flowing inward in the midplane of the disk, and with the warm/hot
phases that surround the midplane flowing outward.
The models suggest a number of results that are in accord with observation,
as well as some novel predictions, including the following. 1) The large-scale
gas density and thermal phase distributions in galaxy disks can be explained as
the result of turbulent heating and spatial couplings. 2) The turbulent
pressures and stresses that drive radial outflows in the warm gas also allow a
reduced circular velocity there. This effect was observed by Swaters, Sancisi
and van der Hulst in NGC 891, a particularly turbulent edge-on disk. The models
predict that the effect should be universal in such disks. 3) They suggest that
a star formation rate like the phenomenological Schmidt Law is the natural
result of global thermohydrodynamical balance, and may not obtain in disks far
from equilibrium. (Abridged)Comment: 37 pages, 1 gif figure, accepted for publication in the Astrophysical
Journa
Students\u27 use of personal technology in the classroom: analyzing the perceptions of the digital generation
Faculty frequently express concerns about students’ personal use of information
and communication technologies in today’s university classrooms. As a requirement
of a graduate research methodology course in a university in Ontario,
Canada, the authors conducted qualitative research to gain an in-depth understanding
of students’ perceptions of this issue. Their findings reveal students’
complex considerations about the acceptability of technology use. Their analysis
of the broader contexts of students’ use reveals that despite a technological revolution,
university teaching practices have remained largely the same, resulting in
‘cultural lag’ within the classroom. While faculty are technically ‘in charge’, students
wield power through course evaluations, surveillance technologies and
Internet postings. Neoliberalism and the corporatisation of the university have
engendered an ‘entrepreneurial student’ customer who sees education as a means
to a career. Understanding students’ perceptions and their technological, social
and political contexts offers insights into the tensions within today’s classrooms
Sex differences in plasma clozapine and norclozapine concentrations in clinical practice and in relation to body mass index and plasma glucose concentrations: a retrospective survey
Background
Clozapine is widely prescribed and, although effective, can cause weight gain and dysglycemia. The dysmetabolic effects of clozapine are thought to be more prevalent in women with this gender on average attaining 17 % higher plasma clozapine concentrations than men.
Methods
We investigated the relationship between dose, body mass index (BMI), plasma glucose concentration, and plasma clozapine and N-desmethylclozapine (norclozapine) concentrations in 100 individuals with a severe enduring mental illness.
Results
Mean (10th/90th percentile) plasma clozapine concentrations were higher for women [0.49 (0.27–0.79) mg/L] compared with men [0.44 (0.26–0.70) mg/L] (F = 2.2; p = 0.035). There was no significant gender difference in the prescribed clozapine dose. BMI was significantly higher in women [mean (95 % CI) = 34.5 (26.0–45.3)] for females compared with 32.5 (25.2–41.0) for males. Overall, BMI increased by 0.7 kg/m 2 over a mean follow-up period of 210 days. A lower proportion, 41 % of women had a fasting blood glucose ≤6.0 mmol/L (<6.0 mmol/L is defined by the International Diabetes Federation as normal glucose handling), compared with 88 % of men (χ2 = 18.6, p < 0.0001).
Conclusions
We have shown that mean BMI and blood glucose concentrations are higher in women prescribed clozapine than in men. Women also tended to attain higher plasma clozapine concentrations than men. The higher BMI and blood glucose in women may relate to higher tissue exposure to clozapine, as a consequence of sex differences in drug metabolism
Starburst99: Synthesis Models for Galaxies with Active Star Formation
Starburst99 is a comprehensive set of model predictions for
spectrophotometric and related properties of galaxies with active star
formation. The models are an improved and extended version of the data set
previously published by Leitherer & Heckman (1995). We have upgraded our code
by implementing the latest set of stellar evolution models of the Geneva group
and the model atmosphere grid compiled by Lejeune et al. (1997). Several
predictions which were not included in the previous publication are shown here
for the first time. The models are presented in a homogeneous way for five
metallicities between Z = 0.040 and 0.001 and three choices of the initial mass
function. The age coverage is 10^6 to 10^9 yr. We also show the spectral energy
distributions which are used to compute colors and other quantities. The full
data set is available for retrieval at
http://www.stsci.edu/science/starburst99/. This website allows users to run
specific models with non-standard parameters as well. We also make the source
code available to the community.Comment: 32 pages, LaTeX. All the Figures and the summary Table are located at
http://www.stsci.edu/science/starburst99/, ApJ accepte
Distribution and biology of prowfish (Zaprora silenus) in the northeast Pacific
The prowfish (Zaprora silenus) is an infrequent component of
bottom trawl catches collected on stock assessment surveys. Based on presence or absence in over 40,000 trawl catches taken throughout Alaskan waters southward to southern California, prowfish are most frequently encountered in the Gulf of Alaska and the Aleutian Islands at the edge of the
continental shelf. Based on data from two trawl surveys, relative abundance indicated by catch per swept area reaches a maximum between 100 m and 200 m depth and is much higher in the Aleutian Islands than in the Gulf of Alaska. Females weigh 3.7% more than males of the same length.
Weight-length functions are W (g) = 0.0164 L2.92 (males) and W = 0.0170 L2.92 (females). Length at age does not
differ between sexes and is described by L = 89.3(1 – e–0.181(t+0.554)), where L is total length in cm and t is age in years. Females reached 50% maturity at a length of 57.0 cm and an age of 5.1 years. Prowfish diet is almost entirely
composed of gelatinous zooplankton, primarily scyphozoa and salps
National Center for Biomedical Ontology: Advancing biomedicine through structured organization of scientific knowledge
The National Center for Biomedical Ontology is a consortium that comprises leading informaticians, biologists, clinicians, and ontologists, funded by the National Institutes of Health (NIH) Roadmap, to develop innovative technology and methods that allow scientists to record, manage, and disseminate biomedical information and knowledge in machine-processable form. The goals of the Center are (1) to help unify the divergent and isolated efforts in ontology development by promoting high quality open-source, standards-based tools to create, manage, and use ontologies, (2) to create new software tools so that scientists can use ontologies to annotate and analyze biomedical data, (3) to provide a national resource for the ongoing evaluation, integration, and evolution of biomedical ontologies and associated
tools and theories in the context of driving biomedical projects (DBPs), and (4) to disseminate the tools and resources of the Center and to identify, evaluate, and communicate best practices of ontology development to the biomedical community. Through the research activities within the Center, collaborations with the DBPs, and interactions with the biomedical community, our goal is to help scientists to work more effectively in the e-science paradigm, enhancing experiment design, experiment execution, data analysis, information synthesis, hypothesis generation and testing, and understand human disease
- …