Test Anxiety and Other Factors as Predictors of Outcome For an Undergraduate University\u27s Examination of Writing Competency

Testing in American schools has increased dramatically in recent years (Cizek & Burg, 2006), increasing the need for research in test anxiety (TA). Writing apprehension, a subcategory of TA, may be of particular concern among students at all levels of education given the recent addition of writing assessments on the SAT and GRE tests. Very few recent studies have examined demographic correlates of TA and the demographics of students in higher education have been changing for some time. These changes include an increase in all categories of nontraditional students. Nontraditional students, by definition, face a particular set of challenges in attending college. They tend to have significant family responsibilities, work and/or other obligations beyond those of traditional students (Ryan, 2003), leaving less time and energy to focus on academics. The research findings on age trends have been variable. However, some research shows a slight decline in the prevalence of TA in the college years (Hembree, 1988; Zeidner, 1998). Early studies have shown that African American students, in general, show higher levels of TA than Caucasian students (Payne, Smith, & Payne, 1983; Rhine & Spaner, 1983). There is minimal research that examines TA specifically for writing exams, or writing apprehension. Earlier studies found that writing apprehension is highly negatively correlated with performance on writing competency assessments and general essays (Daly, 1978; Faigley, Daly, & White, 1981). Given this, it is important to consider the factors that impact writing competency. Graham and Harris (2000) noted much support in the literature for the impact of transcription, or handwriting abilities, on writing competency but also point to self-regulation as another key factor in writing competency. They observed that skilled writers tend to have better self-regulation skills than less skilled writers. In a related area, White and Bruning (2005) found that students\u27 belief systems concerning writing are related to the quality of their writing. The purpose of this study was to assess the relationship between TA, writing apprehension, trait anxiety, and other factors on the outcome of a writing competency examination. The study also assessed the relationship between variables related to nontraditional college students, and TA and writing apprehension. One hundred thirty-seven students at an undergraduate Historically Black College or University (HBCU) participated in the study. Each participant was registered to take the Examination of Writing Competency (EWC) in the semester in which they participated. Participants completed a demographic survey and several measures assessing trait and test anxieties, writing self-regulation, and writing apprehension. The results indicated that only self-regulation during writing was significantly related to writing competency. The relationship was significant only for participants\u27 total score on the EWC and did not predict whether they passed or failed the exam. A discussion of the results, including limitations of the study and directions for future research are presented

A survey of diffuse interstellar bands in the Andromeda galaxy: optical spectroscopy of M31 OB stars

We present the largest sample to-date of intermediate-resolution blue-to-red optical spectra of B-type supergiants in M31 and undertake the first survey of diffuse interstellar bands (DIBs) in this galaxy. Spectral classifications, radial velocities and interstellar reddenings are presented for 34 stars in three regions of M31. Radial velocities and equivalent widths are given for the 5780 and 6283 DIBs towards 11 stars. Equivalent widths are also presented for the following DIBs detected in three sightlines in M31: 4428, 5705, 5780, 5797, 6203, 6269, 6283, 6379, 6613, 6660, and 6993. All of these M31 DIB carriers reside in clouds at radial velocities matching those of interstellar Na I and/or H I. The relationships between DIB equivalent widths and reddening (E(B-V)) are consistent with those observed in the local ISM of the Milky Way. Many of the observed sightlines show DIB strengths (per unit reddening) which lie at the upper end of the range of Galactic values. DIB strengths per unit reddening are found (with 68% confidence), to correlate with the interstellar UV radiation field strength. The strongest DIBs are observed where the interstellar UV flux is lowest. The mean Spitzer 8/24 micron emission ratio in our three fields is slightly lower than that measured in the Milky Way, but we identify no correlation between this ratio and the DIB strengths in M31. Interstellar oxygen abundances derived from the spectra of three M31 H II regions in one of the fields indicate that the average metallicity of the ISM in that region is 12 + log[O/H] = 8.54 +- 0.18, which is approximately equal to the value in the solar neighbourhood

The cost of water: a study of how socioeconomic factors impact water bills in Austin, Texas

Water providers in Central Texas must adapt, expand, and renew drinking water infrastructure in the coming years to contend with increased drought and flooding wrought by climate change, accommodate the region’s growing population, and confront issues of aging and failing infrastructure. Many utilities will turn to increasing water rates to fund these improvements, potentially making water inaccessible for poorer residents. In the face of these looming rate increases, this study uses a lens of water equity to examine how socioeconomic factors, many of which are linked to histories of racism, may affect household water costs. I compare water usage data for both single and multi-family households in Austin, Texas to each household’s housing typology, income, owner-renter status, race/ethnicity, social vulnerability, level of heat exposure and home age using regression analysis, correlational analysis, and descriptive statistics. My findings indicate that a household’s status as an owner or renter was the most statistically significant determinant of its monthly water costs. This suggests that utilities hoping to improve water equity should focus on affordability and conservation programs for renters.Community and Regional Plannin

Rural Teachers’ Burnout, Well-Being, and COVID-19 Related Stress During the Pandemic

To date, researchers have not explored the impact of the COVID-19 pandemic on the well-being of rural teachers specifically. Rural schools already faced long-standing issues of lower salaries, professional isolation, teacher shortages, and technology challenges, suggesting rural teachers may have experienced even higher levels of distress due to the pandemic. Overall, however, teachers from one rural county school system in the southeastern United States reported moderate COVID-19 concerns, low distress, and moderate well-being. Results could reflect responses characteristic of rural resilience. Further study is needed to explore teachers’ unique coping strategies

Transcriptional and Translational Regulatory Responses to Iron Limitation in the Globally Distributed Marine Bacterium Candidatus Pelagibacter ubique

Iron is recognized as an important micronutrient that limits microbial plankton productivity over vast regions of the oceans. We investigated the gene expression responses of Candidatus Pelagibacter ubique cultures to iron limitation in natural seawater media supplemented with a siderophore to chelate iron. Microarray data indicated transcription of the periplasmic iron binding protein sfuC increased by 16-fold, and iron transporter subunits, iron-sulfur center assembly genes, and the putative ferroxidase rubrerythrin transcripts increased to a lesser extent. Quantitative peptide mass spectrometry revealed that sfuC protein abundance increased 27-fold, despite an average decrease of 59% across the global proteome. Thus, we propose sfuC as a marker gene for indicating iron limitation in marine metatranscriptomic and metaproteomic ecological surveys. The marked proteome reduction was not directly correlated to changes in the transcriptome, implicating post-transcriptional regulatory mechanisms as modulators of protein expression. Two RNA-binding proteins, CspE and CspL, correlated well with iron availability, suggesting that they may contribute to the observed differences between the transcriptome and proteome. We propose a model in which the RNA-binding activity of CspE and CspL selectively enables protein synthesis of the iron acquisition protein SfuC during transient growth-limiting episodes of iron scarcity

Perturbations in the Urinary Exosome in Transplant Rejection

Urine exosomes are small vesicles exocytosed into the urine by all renal epithelial cell types under normal physiologic and disease states. Urine exosomal proteins may mirror disease specific proteome perturbations in kidney injury. Analysis methodologies for the exosomal fraction of the urinary proteome were developed for comparing the urinary exosomal fraction versus unfractionated proteome for biomarker discovery. Urine exosomes were isolated by centrifugal filtration of urine samples collected from kidney transplant patients with and without acute rejection, which were biopsy matched. The proteomes of unfractionated whole urine (Uw) and urine exosomes (Ue) underwent mass spectroscopy-based quantitative proteonomics analysis. The proteome data were analyzed for significant differential protein abundances in acute rejection (AR). A total of 1018 proteins were identified in Uw and 349 proteins in Ue. 279 overlapped between the two urinary compartments and 70 proteins were unique to the Ue compartment. Of 349 exosomal proteins identified from transplant patients,220 had not been previously identified in the normal Ue fraction. 11 Ue proteins, functionally involved in an inflammatory and stress response, were more abundant in urine samples from patients with acute rejection, 3 of which are exclusive to the Ue fraction. Ue AR-specific biomarkers(8) were also detected in Uw, but since they were observed at significantly lower abundances in Uw, they were not significant for AR in Uw. A rapid urinary exosome isolation method and quantitative measurement of enriched Ue proteins was applied. Perturbed proteins in the exosomal compartment of urine collected from kidney transplant patients were specific to inflammatory responses, and were not observed in the Ue fraction from normal healthy subjects. Ue specific protein alterations in renal disease provide potential mechanistic insights and offer a unique panel of sensitive biomarkers for monitoring AR

Increasing Efforts to Reduce Cervical Cancer through State-Level Comprehensive Cancer Control Planning

Reducing cervical cancer disparities in the U.S. requires intentional focus on structural barriers such as systems and policy which impact access to human papillomavirus (HPV) vaccination, cervical cancer screening and treatment. Such changes are difficult and often politicized. State comprehensive cancer control (CCC) plans are vehicles that, if designed well, can help build collective focus on structural changes. Study objectives were to identify the prioritization of cervical cancer in state CCC plans, the conceptualization of HPV within these plans, and the focus of plans on structural changes to reduce cervical cancer disparities. Data were gathered by systematic content analysis of CCC plans from 50 states and the District of Columbia from February-June 2014 for evidence of cervical cancer prioritization, conceptualization of HPV, and focus on structural barriers to cervical cancer vaccination, screening or treatment. Findings indicate that prioritization of cervical cancer within state CCC plans may not be a strong indicator of state efforts to reduce screening and treatment disparities. While a majority of plans reflected scientific evidence that HPV causes cervical and other cancers, they did not focus on structural elements impacting access to evidence-based interventions. Opportunities exist to improve state CCC plans by increasing their focus on structural interventions that impact cervical cancer prevention, detection, and treatmentparticularly for the 41% of plans ending in 2015 and the 31% ending between 2016-2020. Future studies should focus on the use of policy tools in state CCC plans and their application to cervical cancer prevention and treatment

Associations of sNfL with clinico-radiological measures in a large MS population

Esclerosi múltiple; Cadena lleugera de neurofilaments sèricsEsclerosis múltiple; Cadena ligera de neurofilamentos séricosMultiple sclerosis; Serum neurofilament light chainObjective Evaluation of serum neurofilament light chain (sNfL), measured using high-throughput assays on widely accessible platforms in large, real-world MS populations, is a critical step for sNfL to be utilized in clinical practice. Methods Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) is a network of healthcare institutions in the United States and Europe collecting standardized clinical/imaging data and biospecimens during routine clinic visits. sNfL was measured in 6974 MS and 201 healthy control (HC) participants, using a high-throughput, scalable immunoassay. Results Elevated sNfL levels for age (sNfL-E) were found in 1238 MS participants (17.8%). Factors associated with sNfL-E included male sex, younger age, progressive disease subtype, diabetes mellitus, impaired renal function, and active smoking. Higher body mass index (BMI) was associated with lower odds of elevated sNfL. Active treatment with disease-modifying therapy was associated with lower odds of sNfL-E. MS participants with sNfL-E exhibited worse neurological function (patient-reported disability, walking speed, manual dexterity, and cognitive processing speed), lower brain parenchymal fraction, and higher T2 lesion volume. Longitudinal analyses revealed accelerated short-term rates of whole brain atrophy in sNfL-E participants and higher odds of new T2 lesion development, although both MS participants with or without sNfL-E exhibited faster rates of whole brain atrophy compared to HC. Findings were consistent in analyses examining age-normative sNfL Z-scores as a continuous variable. Interpretation Elevated sNfL is associated with clinical disability, inflammatory disease activity, and whole brain atrophy in MS, but interpretation needs to account for comorbidities including impaired renal function, diabetes, and smoking.Study funding was provided from the National Institutes of Health (K23NS117883 to E.S.S.; K01MH121582 to K.C.F.; U01NS111678 to P.A.C.), National Multiple Sclerosis Society (RG-1904-33834 to E.S.S.; RG-1904-33800 to P.A.C.), and Biogen

Factors at de novo donorâ specific antibody initial detection associated with allograft loss: a multicenter study

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149234/1/tri13395-sup-0001-FigS1.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149234/2/tri13395_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149234/3/tri13395.pd