6 research outputs found

    The Artisan aphakia intraocular lens in the paediatric eye

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    Bij kinderen met staar, ernstig oogletsel of het syndroom van Marfan moet soms een kunstlens worden geïmplanteerd. Marije Sminia onderzocht de resultaten van de Artisan aphakie-lens, die op de iris wordt gefixeerd. Dit type lens bevindt zich dicht bij de belangrijke binnenste laag van het hoornvlies, het endotheel. De klinische resultaten waren goed. Sminia vond, zelfs na ruim tien jaar, weinig tot geen lensgerelateerde complicaties en een normale endotheelceldichtheid van het hoornvlies. In subgroepen werden een grote spreiding in endotheelceldichtheid en veranderingen in de structuur van het endotheel gevonden. De implicaties daarvan zijn nog onduidelijk. Sminia concludeert dat de Artisan aphakie-lens goed voldoet; de resultaten zijn zeker even goed als die van andere, vergelijkbare soorten kunstlenzen

    Axial eye length growth and final refractive outcome after unilateral paediatric cataract surgery

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    AIM: To compare the axial eye length growth of the two fellow eyes within one patient after unilateral paediatric cataract surgery and to asses changes in refraction and keratometry. Patients/ METHODS: A retrospective study in 90 eyes of 45 patients was performed. The 45 patients were divided into group 1 (patients younger than 18 months at the time of surgery, n=25) and group 2 (patients 18 months or older at the time of surgery, n=20). The axial eye length, spherical equivalent refraction and keratometry were measured during surgery and at follow up. All outcome data in the operated eyes were compared with the outcome data of the fellow non- operated eyes. The students t-test was used for statistical analysis. Values of p <0.05 were considered statistically significant. RESULTS: In group 1 the absolute growth in mm of the operated eyes was borderline statistically significant less than the fellow non- operated eyes (p=0.049). No statistically significant difference in the rate of axial growth between the two eyes was found (p=0.25). A larger myopic shift (p=3.85E-5) and a larger change in keratometry (p=0.02) was found in the operated eyes. In group 2 no statistically significant differences were found between the two eyes. CONCLUSIONS: We did not find a statistically significant difference in axial length growth between the operated eyes and fellow non-operated eyes in our unilateral paediatric cataract patient

    Long-term follow-up of the corneal endothelium after artisan lens implantation for unilateral traumatic and unilateral congenital cataract in children: two case series

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    PURPOSE: To retrospectively estimate the long-term corneal endothelial cell loss in children after perforating corneal trauma and implantation of an iris-fixated anterior-chamber intraocular lens (IOL), either the Artisan aphakia lens or the Artificial Iris Implant, and to compare this corneal endothelial cell loss to that in children who received an Artisan aphakia lens to correct aphakia after cataract extraction for unilateral congenital cataract. METHODS: A retrospective study was performed, evaluating the charts and endothelial photographs of 6 patients with unilateral traumatic cataract, with a mean age at IOL implantation of 9.5 years (range: 5.8-12.8 years) and a mean follow-up after IOL implantation of 10.5 years (range: 8.0-14.7 years), and of 3 children who were operated on for unilateral congenital cataract at a mean age of 2.7 years and who received an Artisan aphakia IOL, with a mean follow-up after IOL implantation of 9.5 years (range: 4.7-14.5 years). Parameters that were studied were central endothelial cell density (CECD) in both the operated and the normal eye at the last follow-up visit, percentage of cell loss in the operated eye compared with the normal eye, and length and location of the corneal scar in the injured eye. RESULTS:: In the traumatic cataract group, CECD was, on average, 41% (range: 22%-58%) lower in the operated eye (1.647 +/- 322 [SD] cells/mm) than the normal eye (2.799 +/- 133 cells/mm). A significant negative linear correlation was found between the length of the corneal perforation scar and CECD. In the congenital cataract group, no statistical difference in CECD was found between the operated (3.323 +/- 410 cells/mm) and the unoperated (3.165 +/- 205 cells/mm) eye. CONCLUSION: Endothelial cell loss 10.5 years after iris-fixated IOL implantation for traumatic cataract was substantial and related to the length of the corneal scar of the original trauma. In children operated on for congenital cataract, no difference was found in CECD in the operated and unoperated eyes 9.5 years after Artisan aphakia IOL implantatio

    Anomalous relation between axial length and retinal thickness in amblyopic children

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    To investigate the relationship between retinal thickness and axial length in amblyopic eyes compared to healthy eyes. In this observational, transversal study, 36 amblyopic children and 30 healthy controls underwent full ophthalmological and orthoptic examinations, volume scanning of the macula with spectral domain optical coherence tomography (3D OCT-1000; Topcon Corporation, Tokyo, Japan), and measuring of axial length using the IOLMaster (Carl Zeiss Meditec AG, Jena, Germany). The average pericentral retinal thickness was calculated. A strong correlation was observed between the axial lengths of both eyes in the control group (R = 0.98, P < 0.01) and between the axial lengths of the amblyopic and fellow eye in the amblyopic group (R = 0.77, P < 0.01); the amblyopic and their fellow eyes were significantly shorter than the nonamblyopic control eyes. The pericentral retinal thickness of both eyes of an individual is highly correlated in nonamblyopic controls (R = 0.92, P < 0.01) and in amblyopic children (R = 0.82, P < 0.01). There is no significant difference in mean pericentral retinal thickness between healthy, amblyopic, and fellow eyes. In healthy eyes a moderate inverse correlation exists between axial length and pericentral retinal thickness (R = -0.41, P = 0.02); this relationship was not found in the amblyopic eyes or the normal fellow eye. In this patient cohort, there was an anomalous relation between the axial length and the pericentral retinal thickness in both amblyopic and their fellow eye
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