A perforating pilomatricomal horn on the arm of an 11-year-old girl

Cutaneous horns are uncommon in adults and rare in the pediatric population. Although verruca vulgaris, solar keratosis, and squamous cell carcinoma are more common entities that can present as cutaneous horns in the general population, conditions such as molluscum contagiosum, juvenile xanthgranuloma, and pyogenic granuloma have been reported causes in the pediatric population. We present a case of a perforating pilomatricoma presenting as a cutaneous horn in an 11 year old girl

A perforating pilomatricomal horn on the arm of an 11-year-old girl

Cutaneous horns are uncommon in adults and rare in the pediatric population. Although verruca vulgaris, solar keratosis, and squamous cell carcinoma are more common entities that can present as cutaneous horns in the general population, conditions such as molluscum contagiosum, juvenile xanthgranuloma, and pyogenic granuloma have been reported causes in the pediatric population. We present a case of a perforating pilomatricoma presenting as a cutaneous horn in an 11 year old girl

Transferrin predicts trimethylamine-N-oxide levels and is a potential biomarker of cardiovascular disease

Introduction: Trimethylamine-N-oxide (TMAO) is a circulating biomarker associated with cardiovascular disease (CVD). Production of TMAO is facilitated by gut microbiota and dependent on micronutrients such as choline, betaine, and L-carnitine, present in foods such as red meat and eggs. Hypothesis: We sought to predict serum TMAO quartile levels among healthy individuals at increased risk of CVD using clinical data via an ordinal logistic model. Methods: Data from participants (n = 127) enrolled in a longitudinal observational study on CVD were used to build a predictive model for TMAO using ordinal logistic regression with demographic variables and 40 other variables considered related to CVD risk. First, univariate models for each covariate were tested (with serum TMAO quartiles as the dependent variable), and only variables with P < 0.30 were evaluated further. Second, demographic variables (age, gender, white vs. non-white race) were included in a multivariable model with each previously identified independent variable controlling for potential confounding. Last, the final model included fixed demographics and candidates from the confounder-adjusted model with P < 0.10. Results: Eight candidate variables were included in the final model, with only transferrin, high-density lipoprotein cholesterol (HDL-C) and race (white vs. non-white) showing significant associations with TMAO. Participants had 0.16 (Q2), 0.31 (Q3), and 0.20 (Q4) odds of being in a higher TMAO quartile compared with participants in the lowest transferrin quartile. Non-white participants had 2.92 times higher odds of being in the highest TMAO quartile compared to white individuals. Participants in the second quartile of HDL-C had 2.68 times higher odds of being in a higher TMAO quartile compared with participants in the lowest HDL-C quartile. Conclusions: Transferrin demonstrated a significant predictive association with TMAO and may represent a novel potential biomarker of increased CVD risk worthy of further study. These results warrant further examination of iron, metabolism, homeostasis, and gut microbiome to better understand and mitigate known increased CVD risk

Inclusive gamma K0(s) lambda0 and anti-lambda0 production by 205-GeV/c pion proton interactions

Neutral decays and {gamma} conversions have been analyzed in an exposure of the NAL 30 hydrogen bubble chamber to 205 GeV/c pions. This paper presents preliminary results on inclusive cross sections for the production of {Upsilon}'s, K{sub s}{sup 0}'s, {Lambda}{sup 0}'s and {bar {Lambda}}{sup 0}'s by 205 GeV/c {pi}{sup -}p interactions. The experiment was done in the NAL 30 hydrogen bubble chamber. Six hundred and sixty-four neutral decays (or conversions) found in a scan of 3058 {pi}{sup -}p interactions were measured. During measurement, three percent of these events were rejected as not pointing to the primary vertex. Another 29% were discarded by a fiducial volume cut on the neutral vertex

Search for anti-neutrino induced muon+ e- events

The authors have examined 1200 interactions with visible energies greater than 7.5 GeV produced by an anti-neutrino beam in the Fermilab 15-foot bubble chamber filled with a light neon hydrogen mixture. They have found one event with a {mu}{sup +}e{sup -} and hadrons in the final state, but with no evidence of strange particle production. This event may be an example of dilepton production by an anti-neutrino interaction, but other interpretations are possible. With 90% confidence, they conclude that the rate for the process {bar {nu}} + N {yields} e{sup -} + {mu}{sup +} + hadrons is {le} .8% of charged current anti-neutrino interactions with visible energy &gt; 7.5 GeV

Measurement of y-Distributions for High Energy Antineutrino Scattering in Hydrogen-Neon

Distributions in the scaling variable y are presented based on a study of approximately 700 antineutrino events in the energy range 10-200 GeV obtained using the Fermilab 15-ft bubble chamber filled with a light Hydrogen-Neon mixture. The distributions are inconsistent with a (1 -y){sup 2} form predicted by the simple quark parton model of the nucleon without antiquarks, but can be well fitted assuming a relative antiquark contribution of (10 {+-} 5)%. For small values of the Bjorken scaling variable (x &lt; 0.1) the y-distribution can be well fitted assuming a relative antiquark contribution of (20 {+-} 5)%. For events at small x in the energy range 30-200 GeV the y-distribution is in good agreement with the results reported by the HPWF group