75 research outputs found

    Analysis of Noise Coupling from Printed Circuit Board to Shielding Enclosure

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    The power distribution network in a printed circuit board (PCB) inside a compact-size enclosure is an effective path for high-speed digital noise to be coupled to the RF receivers inside the same enclosure, causing RF interference (RFI) issues. This noise coupling mechanism from PCB to shielding enclosure is investigated in this paper using the cavity model and the segmentation technique. In this approach, the structure of an enclosure with a PCB inside is divided into cavities with both horizontal and vertical connections. Modeling result agrees well with full wave simulations, and the simulation time is considerably reduced. Furthermore, the relationship among the noise coupling, the PCB-related resonances, and the enclosure-related resonances is studied as well

    A Study of the Probe Induced Disturbances on the Near-Field Measurement

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    Numerical simulations were used to investigate the disturbance introduced by placing a small magnetic loop probe in the near field of a driven loop. In the absence of the loop probe, the numerical simulations were compared with an approximate closed-form analytical expression for the magnetic field produced by the driven loop. The agreement between the approximate analytical results and the simulation was good. The next set of simulations was based on a physical model that included the probe and showed that the probe does exert an effect on the field being measured. Examples of these simulations and their implications on measurements will be discussed

    Divergent Transcriptional Regulatory Logic at the Intersection of Tissue Growth and Developmental Patterning

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    The Yorkie/Yap transcriptional coactivator is a well-known regulator of cellular proliferation in both invertebrates and mammals. As a coactivator, Yorkie (Yki) lacks a DNA binding domain and must partner with sequence-specific DNA binding proteins in the nucleus to regulate gene expression; in Drosophila, the developmental regulators Scalloped (Sd) and Homothorax (Hth) are two such partners. To determine the range of target genes regulated by these three transcription factors, we performed genome-wide chromatin immunoprecipitation experiments for each factor in both the wing and eye-antenna imaginal discs. Strong, tissue-specific binding patterns are observed for Sd and Hth, while Yki binding is remarkably similar across both tissues. Binding events common to the eye and wing are also present for Sd and Hth; these are associated with genes regulating cell proliferation and “housekeeping” functions, and account for the majority of Yki binding. In contrast, tissue-specific binding events for Sd and Hth significantly overlap enhancers that are active in the given tissue, are enriched in Sd and Hth DNA binding sites, respectively, and are associated with genes that are consistent with each factor's previously established tissue-specific functions. Tissue-specific binding events are also significantly associated with Polycomb targeted chromatin domains. To provide mechanistic insights into tissue-specific regulation, we identify and characterize eye and wing enhancers of the Yki-targeted bantam microRNA gene and demonstrate that they are dependent on direct binding by Hth and Sd, respectively. Overall these results suggest that both Sd and Hth use distinct strategies – one shared between tissues and associated with Yki, the other tissue-specific, generally Yki-independent and associated with developmental patterning – to regulate distinct gene sets during development

    using Near-Field Scanning to Predict Radiated Fields

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    Near-field scanning has often been used to measure and characterize magnetic fields surrounding individual integrated circuits (IC) and high speed digital electronic circuits. The paper describes the use of near-field scanning data, performed in a typical laboratory bench top environment, to predict radiated electromagnetic interference (EMI) in a typical product environment. The product environment may include enclosures and apertures. The approach begins by acquiring sufficient near-field scanning data to allow representation of an unintentional radiating source by an equivalent surface current distribution. The equivalent current distribution is used as a source in numerical full wave modeling. The agreement between direct full wave simulation results and full wave simulation results using equivalent sources works well under certain assumptions

    Yorkie Promotes Transcription by Recruiting a Histone Methyltransferase Complex

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    SummaryHippo signaling limits organ growth by inhibiting the transcriptional coactivator Yorkie. Despite the key role of Yorkie in both normal and oncogenic growth, the mechanism by which it activates transcription has not been defined. We report that Yorkie binding to chromatin correlates with histone H3K4 methylation and is sufficient to locally increase it. We show that Yorkie can recruit a histone methyltransferase complex through binding between WW domains of Yorkie and PPxY sequence motifs of NcoA6, a subunit of the Trithorax-related (Trr) methyltransferase complex. Cell culture and in vivo assays establish that this recruitment of NcoA6 contributes to Yorkie’s ability to activate transcription. Mammalian NcoA6, a subunit of Trr-homologous methyltransferase complexes, can similarly interact with Yorkie’s mammalian homolog YAP. Our results implicate direct recruitment of a histone methyltransferase complex as central to transcriptional activation by Yorkie, linking the control of cell proliferation by Hippo signaling to chromatin modification

    Applications of a Hybrid Manufacturing Process for Fabrication and Repair of Metallic Structures

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    Since its appearance, rapid prototyping technology has been of interest to various industries that are looking for a process to produce/build a part directly from a CAD model in a short time. Among them, the direct metal deposition process is the only process which directly manufactures a fully dense metal part without intermediate steps. However, challenges of the direct metal deposition process include building overhang structures, producing precision surfaces, and making parts with complex structures. Coupled between the additive and the subtractive processes into a single workstation, the integrated process, or hybrid process, can produce a metal part with machining accuracy and surface finish. Therefore, the hybrid process is potentially a very competitive process to fabricate and repair metallic structures. This paper summarizes the current development of the hybrid process to process high temperature metallic materials, including tool steel and Ti64. Research in simulation and modeling, process development, and actual part building and repair are discussed

    Closed-form Expressions for Determining Approximate PMC Boundaries Around an Aperture in a Metal Cavity Wall

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    Modern electronic systems may use mixed RF/digital technologies to achieve various functionalities, which leads to various intra-system interference problems including the RF interference from noisy digital circuits to sensitive RF receivers, especially when the overall system is contained in a metal enclosure. A fast method based on a cavity formulation can be used to estimate the internal noise coupling mechanisms inside the enclosure. This method assumes that only the TMz0 mode exists inside the enclosure, i.e., the electric field along the z-direction is constant. The cavity formulation fails in the region adjacent to an aperture in an enclosure wall, since the aperture introduces higher order modes. The developed closed-form expressions compute the Ez-field variation along the z-direction. Thus, they can be used to estimate the breakpoint where the cavity method is no longer effective

    Modeling and Simulation of a Laser Deposition Process

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    A laser deposition process involves the supply of metallic powders into a laser-heated spot where the powder is melted and forms a melt puddle which quickly solidifies into a bead. In order to design an effective system, the laser beam, the powder beam, and their interactions need to be fully understood. In this paper, the laser-material interaction within the melt pool is reported using a multi-scale model: A macroscopic model to model mass, heat, and momentum transfer. Experiments were also conducted to validate the simulation model

    Field Extraction from Near Field Scanning for a Microstrip Structure

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    Currents associated with high-speed digital devices have significant impacts on EMI problems in VLSI design and operation. In this paper, a simple transmission line model was implemented as an initial step to represent the EMI mechanisms associated with an IC package. Numerical modeling results were compared with near field scanning measurements and show that the magnetic field deduced from the measurements agrees well with the numerical predictions

    Development and Application of a High-Resolution Thin-Film Probe

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    This paper documents the development, characterization, and application of a high-resolution thin-film magnetic-field probe. Probe diameter ranged from 5-ÎĽm to 100-ÎĽm. The 100-ÎĽm probe exhibits a 250-7ÎĽm improvement in spatial resolution compared to a conventional loop probe, measured at a height of 250 ÎĽm over differential traces with a 118-ÎĽm spacing. Electric field rejection was improved using shielding and using a 180-degree hybrid junction to separate common-mode (electric field) and differential-mode (primarily magnetic field) coupling. A network analyzer with narrow band filtering was used to detect the relatively weak signal from the probe and to allow detection of phase information. An application of the probe is demonstrated where the probe is used to identify the magnitude and phase of magnetic fields produced by currents in very closely-spaced IC package pins
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