72 research outputs found
Research of the overall chemical and amino acid composition of meat from young animals of new sheep genotypes
The paper presents the results of the investigation of the overall chemical composition (mass fraction of moisture, fat, protein and ash) and the amino acid composition of mutton from the experimental animals of new genotypes: Sovetsky Merino x Dzhalginsky Merino and Sovetsky Merino x Stavropolsky breed. As a control, meat of purebred Sovetsky Merino was studied. The experimental and control rams were slaughtered at the age of 8 months by the conventional technology. Meat samples for laboratory examination were taken a day after slaughter. The results of the analysis of the overall chemical composition showed that lamb meat of new genotypes had lower moisture content and higher content of fat and protein compared to the control. Analysis of the amino acid composition of meat proteins of genotypes Sovetsky Merino x Dzhalginsky Merino and Sovetsky Merino x Stavropolsky breed revealed lower content of essential amino acids compared to the control. Comparison of amino acid scores showed that the amino acid composition of meat proteins from the experimental animals was limited by valine and lysine, respectively. It was concluded by the results of the investigations of the amino acid composition of proteins that the biological full value of proteins of mutton from new genotypes was 22.9% and 30.3% lower than that of the control
Prognostic factors of intracranial purulent-septic complications of combat-related gunshot penetrating skull and brain wounds.
Purpose β to anaΒlyze the structure of intracranial purulent-septic complications (IPSC), determine the factors influencing development of purulent-septic complications in patients with combat-related gunshot penetrating skull and brain wounds (CRPSBW), determine the effect of intracranial PSC on patientsβ outcomes. A prospective analysis of results of exaΒmination and treatment of 121 patients was performed. All patients had gunshot penetrating skull and brain wounds sustained in combat conditions during a local armed conflict in the Eastern Ukraine. Evaluation of treatment outcome included analysis of mortality in 1 month (survived/died) and dichotomous Glasgow Outcome Scale (GOS) score in 12 months (favorable/unfavorable outcome). 121 wounded men aged 18 to 56 (average, 34.1Β±9.1) were included in the study. Intracranial purulent-septic complications (IPSC) were diagnosed in 14 (11.6%) gunshot CRPSBW patients. The following prognostic factors had statistically significantly correlation with the risk of intracranial purulent-septic complications development: wound liquorrhea on admission (p = 0.043), intraventricular hemorrhage (p = 0.007), bone fragments left in the wound (p = 0.0152), andΒ duration of inflow-outflow wound drainage for more than 3 days (p= 0.0123). Intracranial PSC patients had mortality rate of 50%, and only 14.3% of those patients had a favorable outcome according to GOS score in one year. Presence of intracranial PSC had statistically significant association with mortality rate (p=0.0091) and GOS score in one year (p=0.0001)
Relief and geology of the north polar region of the planet Venus
Description of topographic features is given for the North polar region of the planet Venus. Principal geomorphic types of terrain are characterized as well as their geologic relations. Relative ages of geologic units in Venus North polar region are discussed
ΠΠ°ΡΠΈΠ°ΡΠΈΡ ΠΏΠΈΠ³ΠΌΠ΅Π½ΡΠ°ΡΠΈΠΈ ΡΠ°Π΄ΡΠΆΠΊΠΈ Π³Π»Π°Π· Π±Π΅Π»ΠΎΡΡΡΡΠΊΠΎΠΉ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ Π² ΡΠ²ΡΠ·ΠΈ Ρ ΠΏΠΎΠ»ΠΈΠΌΠΎΡΡΠΈΠ·ΠΌΠΎΠΌ Π³Π΅Π½ΠΎΠ² HERC2 ΠΈ OCA2
The human genetic phenotyping is one of the most intensely developing area of forensic genetics. Externally visible traits, including eye color, can be predicted by analyzing single nucleotide polymorphisms with a high predictive rate. We studied the polymorphisms rs12913832 and rs1800407 in the HERC2 and OCA2 genes, respectively, to evaluate its prognostic availability in relation to the iris pigmentation of the Belarusian population. For this, both eye images and DNA samples were collected from 314 individuals to analyze the key polymorphisms by the TaqMan assay. Our data confirmed a relevance of rs12913832:A>G and rs1800407:G>A in the prediction context. The highest values of the sensitivity (SE = 0.94) and the specificity (SP = 0.90) were obtained for rs12913832, demonstrating the high efficiency of this marker as a classifier of phenotypic groups. The presence of the ancestral dominant allele rs12913832-A causes a dark (brown) iris pigmentation, how- ever, the heterozygous state rs12913832:GA includes a range of mixed variants. The predictive value of rs1800407 for the genetic phenotyping is highly significant (SE = 0.98), but has a low specificity (SP = 0.14), thus rs1800407, not being an effective classifier, can be used as an auxiliary in the eye color predictive model. The analysis of a cumulative impact of the both poly- morphisms on the iris color variation shows their high prospects for the genetic phenotyping of the Belarusian population.ΠΠ΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΡΠ΅Π½ΠΎΡΠΈΠΏΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ° β Π½ΠΎΠ²ΠΎΠ΅, ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎ ΡΠ°Π·Π²ΠΈΠ²Π°ΡΡΠ΅Π΅ΡΡ Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½ΠΈΠ΅ ΠΊΡΠΈΠΌΠΈΠ½Π°Π»ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π³Π΅Π½Π΅ΡΠΈΠΊΠΈ. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΎΡΠ½ΠΎΠ² ΡΠ²Π΅ΡΠΎΠ²ΠΎΠΉ Π²Π°ΡΠΈΠ°ΡΠΈΠΈ Π³Π»Π°Π· ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΠ΄Π½ΠΈΠΌ ΠΈΠ· Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΡΡΠ΅Π΄ΠΈ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄ΠΎΠ², Π½Π°ΡΠ΅Π»Π΅Π½Π½ΡΡ
Π½Π° ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΈΠ΅ ΠΎΠ±Π»ΠΈΠΊΠ° Π½Π΅ΠΈΠ·Π²Π΅ΡΡΠ½ΠΎΠ³ΠΎ ΠΈΠ½Π΄ΠΈΠ²ΠΈΠ΄Π° ΠΏΠΎ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠ°ΠΌ Π΅Π³ΠΎ ΠΠΠ. Π Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΠ΅ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΠΏΠΎΠ»ΠΈΠΌΠΎΡΡΠΈΠ·ΠΌΠΎΠ² rs12913832 ΠΈ rs1800407 Π² Π³Π΅Π½Π°Ρ
HERC2 ΠΈ ΠΠ‘A2 ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²Π΅Π½Π½ΠΎ Π² ΡΠ²ΡΠ·ΠΈ Ρ ΠΏΠΈΠ³ΠΌΠ΅Π½ΡΠ°ΡΠΈΠ΅ΠΉ ΡΠ°Π΄ΡΠΆΠΊΠΈ Π³Π»Π°Π· Π±Π΅Π»ΠΎΡΡΡΡΠΊΠΎΠΉ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ ΠΈ Π΄Π°Π½Π° ΠΎΡΠ΅Π½ΠΊΠ° ΠΈΡ
ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π΄Π»Ρ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ΅Π½ΠΎΡΠΈΠΏΠΈΡΠΎΠ²Π°Π½ΠΈΡ. ΠΠΎΠ»ΡΡΠ΅Π½Π½ΡΠ΅ Π΄Π°Π½Π½ΡΠ΅ ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠ΄ΠΈΠ»ΠΈ Π·Π½Π°ΡΠΈΠΌΡΠΉ Π²ΠΊΠ»Π°Π΄ Π² ΡΠ²Π΅ΡΠΎΠ²ΡΡ Π²Π°ΡΠΈΠ°ΡΠΈΡ ΡΠ°Π΄ΡΠΆΠΊΠΈ Π³Π»Π°Π· rs12913832:A>G ΠΈ rs1800407:G>A. ΠΡΡΠΎΠΊΠΈΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΡ ΡΡΠ²ΡΡΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ (SE = 0,94) ΠΈ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΡΡΠΈ (SP = 0,90) Π±ΡΠ»ΠΈ ΠΏΠΎΠ»ΡΡΠ΅Π½Ρ Π΄Π»Ρ rs12913832, ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠ΄ΠΈΠ² ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π΄Π°Π½Π½ΠΎΠ³ΠΎ ΠΌΠ°ΡΠΊΠ΅ΡΠ° Π΄Π»Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΊΠ»Π°ΡΡΠΈΡΠΈΠΊΠ°ΡΠΎΡΠ° ΡΠ΅Π½ΠΎΡΠΈΠΏΠΈΡΠ΅ΡΠΊΠΈΡ
Π³ΡΡΠΏΠΏ. ΠΠ°Π»ΠΈΡΠΈΠ΅ ΠΏΡΠ΅Π΄ΠΊΠΎΠ²ΠΎΠ³ΠΎ Π΄ΠΎΠΌΠΈΠ½Π°Π½ΡΠ½ΠΎΠ³ΠΎ Π°Π»Π»Π΅Π»Ρ rs12913832-A ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»ΠΈΠ²Π°Π΅Ρ ΡΠ΅ΠΌΠ½ΡΡ ΠΏΠΈΠ³ΠΌΠ΅Π½ΡΠ°ΡΠΈΡ ΡΠ°Π΄ΡΠΆΠΊΠΈ, ΠΎΠ΄Π½Π°ΠΊΠΎ Π³Π΅ΡΠ΅ΡΠΎΠ·ΠΈΠ³ΠΎΡΠ½ΠΎΠ΅ Π½ΠΎΡΠΈΡΠ΅Π»ΡΡΡΠ²ΠΎ rs12913832:GA Π²ΠΊΠ»ΡΡΠ°Π΅Ρ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΡΠΉ ΡΠΏΠ΅ΠΊΡΡ ΡΠΌΠ΅ΡΠ°Π½Π½ΡΡ
Π²Π°ΡΠΈΠ°Π½ΡΠΎΠ². ΠΠ΄Π½ΠΎΠ½ΡΠΊΠ»Π΅ΠΎΡΠΈΠ΄Π½ΡΠΉ ΠΏΠΎΠ»ΠΈΠΌΠΎΡΡΠΈΠ·ΠΌ rs1800407 Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΡΠ΅ΡΡΡ Π²ΡΡΠΎΠΊΠΎΠΉ ΡΡΠ²ΡΡΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΡΡ (SE = 0,98), ΠΎΠ΄Π½Π°ΠΊΠΎ ΠΈΠΌΠ΅Π΅Ρ Π½ΠΈΠ·ΠΊΠΎΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΡΡΠΈ (SP = 0,14), ΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎ, Π΄Π°Π½Π½ΡΠΉ ΠΌΠ°ΡΠΊΠ΅Ρ, Π½Π΅ ΡΠ²Π»ΡΡΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΠΌ ΠΊΠ»Π°ΡΡΠΈΡΠΈΠΊΠ°ΡΠΎΡΠΎΠΌ, ΠΌΠΎΠΆΠ΅Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡΡΡ ΡΠΎΠ»ΡΠΊΠΎ ΠΊΠ°ΠΊ Π²ΡΠΏΠΎΠΌΠΎΠ³Π°ΡΠ΅Π»ΡΠ½ΡΠΉ ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½Ρ Π΄Π»Ρ ΠΏΡΠ΅Π΄ΡΠΊΠ°Π·Π°Π½ΠΈΡ ΡΠ²Π΅ΡΠ° Π³Π»Π°Π·. ΠΡΠ΅Π½ΠΊΠ° ΡΠΎΠ²ΠΎΠΊΡΠΏΠ½ΠΎΠ³ΠΎ Π²ΠΊΠ»Π°Π΄Π° ΠΈΠ·ΡΡΠ΅Π½Π½ΡΡ
ΠΏΠΎΠ»ΠΈΠΌΠΎΡΡΠΈΠ·ΠΌΠΎΠ² Π² ΡΠ²Π΅ΡΠΎΠ²ΡΡ Π²Π°ΡΠΈΠ°ΡΠΈΡ ΡΠ°Π΄ΡΠΆΠΊΠΈ Π³Π»Π°Π· Π±Π΅Π»ΠΎΡΡΡΡΠΊΠΎΠΉ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°Π΅Ρ ΠΈΡ
Π²ΡΡΠΎΠΊΠΈΠΉ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π» Π΄Π»Ρ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ΅Π½ΠΎΡΠΈΠΏΠΈΡΠΎΠ²Π°Π½ΠΈΡ
World Federation for Interventional Stroke Treatment (WIST) multispecialty training guidelines for endovascular stroke intervention
Introduction: Today, endovascular treatment (EVT) is the therapy of choice for strokes due to acute large vessel occlusion, irrespective of prior thrombolysis. This necessitates fast, coordinated multi-specialty collaboration. Currently, in most countries, the number of physicians and centres with expertise in EVT is limited. Thus, only a small proportion of eligible patients receive this potentially life-saving therapy, often after significant delays. Hence, there is an unmet need to train a sufficient number of physicians and centres in acute stroke intervention in order to allow widespread and timely access to EVT. Aim: To provide multi-specialty training guidelines for competency, accreditation and certification of centres and physicians in EVT for acute large vessel occlusion strokes. Material and methods: The World Federation for Interventional Stroke Treatment (WIST) consists of experts in the field of endovascular stroke treatment. This interdisciplinary working group developed competency β rather than time-based β guidelines for operator training, taking into consideration traineesβ previous skillsets and experience. Existing training concepts from mostly single specialty organizations were analysed and incorporated. Results: The WIST establishes an individualized approach to acquiring clinical knowledge and procedural skills to meet the competency requirements for certification of interventionalists of various disciplines and stroke centres in EVT. WIST guidelines encourage acquisition of skills using innovative training methods such as structured supervised high-fidelity simulation and procedural performance on human perfused cadaveric models. Conclusions: WIST multispecialty guidelines outline competency and quality standards for physicians and centres to perform safe and effective EVT. The role of quality control and quality assurance is highlighted
World Federation for Interventional Stroke Treatment (WIST) multispecialty training guidelines for endovascular stroke intervention
IntroductionToday, endovascular treatment (EVT) is the therapy of choice for strokes due to acute large vessel occlusion, irrespective of prior thrombolysis. This necessitates fast, coordinated multi-specialty collaboration. Currently, in most countries, the number of physicians and centres with expertise in EVT is limited. Thus, only a small proportion of eligible patients receive this potentially life-saving therapy, often after significant delays. Hence, there is an unmet need to train a sufficient number of physicians and centres in acute stroke intervention in order to allow widespread and timely access to EVT.AimTo provide multi-specialty training guidelines for competency, accreditation and certification of centres and physicians in EVT for acute large vessel occlusion strokes.Material and methodsThe World Federation for Interventional Stroke Treatment (WIST) consists of experts in the field of endovascular stroke treatment. This interdisciplinary working group developed competency β rather than time-based β guidelines for operator training, taking into consideration trainees' previous skillsets and experience. Existing training concepts from mostly single specialty organizations were analysed and incorporated.ResultsThe WIST establishes an individualized approach to acquiring clinical knowledge and procedural skills to meet the competency requirements for certification of interventionalists of various disciplines and stroke centres in EVT. WIST guidelines encourage acquisition of skills using innovative training methods such as structured supervised high-fidelity simulation and procedural performance on human perfused cadaveric models.ConclusionsWIST multispecialty guidelines outline competency and quality standards for physicians and centres to perform safe and effective EVT. The role of quality control and quality assurance is highlighted
External parameters of a coupling between partially filled and hollow waveguides
Knowledge of the external parameters of a planar-transverse butt joint between partially filled and hollow waveguides is necessary in designing waveguide devices having a dielectric filler: phase shifters, polarizers, attenuators, filters based on dielectric resonators, etc. The present work considers an approximate procedure for determining the external parameters of such a coupling
Theoretical Study of Sulfines and Sulfenes. Similarities and Differences in Structure and Reactivity. A New View
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