The development of a methodology for the evaluation of installed CAPM system’s effectiveness and efficiency

The objective of this work was to design, develop and evaluate an audit for a Computer Aided Production Management (CAPM) system. Such systems, despite their costs of purchase and implementation, find wide application in industry but there is still considerable debate as to their contribution to the overall performance of a company. A variety of possible methodologies were explored. However, it was found that most of the existing analytical techniques tended to focus on a comparison of systems with respect to best practice or to require data that a company was unlikely to have. Best practice is not an absolute measure, nor does it take account of different company types and their individual requirements. A flexible methodology, 'the CAPM Audit', designed to establish the effectiveness and efficiency of any installed CAPM system, has been developed. The audit is a development of the Delphi approach and is designed to establish the contribution of the CAPM system to the company's overall competitive position. In its development, a generic model for any CAPM system was devised to facilitate analysis without reference to any particular technology, management mode, or manufacturing control system. The audit developed (in the form of a workbook) consists of four stages: stage one establishes the context; stage two determines the underlying architecture of the system; stage three quantifies the contribution to the company's competitive position; and stage four identifies the causes of any failure of the CAPM system. The design of the audit is such that: it enables a systematic investigation of the effectiveness and efficiency of an installed CAPM system to be completed; it enables the CAPM system's contribution to the company to be identified; and it also enables any inadequacies to be determined

The Effect of Customers’ Emotion on Service Recovery Strategy in IT Service Failures

IT service support staff that deals with customer service inquiries online plays a key role in ensuring customer satisfaction and shaping customer experience. In reaction to service failures customers may exhibit some emotions that may influence service support staff’s response. Without a face-to-face interaction with customers, service support cannot detect the emotional signals sent out from customers. Instead service providers must rely on the content of email or online form received to detect any emotional cues. Using data from an issues tracking system, we will empirically test (i) the effect of customer’s emotion encoded in text content on service support staff’s response and (ii) the effect of service recovery strategy on customer’s sentiment on service quality when the service is recovered. Thus, the study will enrich our knowledge in the relationship between customer emotion and service recovery strategy in the context of IT service support

The roles of opportunity processes in a social business model: insights from China’s e-commerce villages

A social enterprise connects a social purpose with economic rationality and market-based approaches to solve recognized social needs. However, opportunities often far outstrip the resources available to address these needs, making the design of a social business model challenging. It has been suggested that opportunity processes in a social enterprise enable economic, social, and environmental resources to reinforce one another in novel ways. Based on an in-depth case study of a large social enterprise in China, we find that opportunity processes are important components of a social business model. New opportunities are created deliberately while building a social business model, leading to the large-scale mobilization of participation in e-commerce activities. We differentiate endogenous and exogenous opportunities to clarify the roles of various opportunity processes. This study potentially enriches our knowledge of the relationships between opportunity processes and the construction of a successful social business model in the context of e-commerce

THE ROLE OF IT-DRIVEN ENTREPRENEURIAL PROCESSES IN BUSINESS MODEL DEVELOPMENT

Ph.DDOCTOR OF PHILOSOPH

Information System Strategy for Opportunity Discovery and Exploitation: Insights from Business Model Transformation

For a large enterprise to design a new business model, business managers are unlikely to determine the precise set of choices required to create and capture value. Instead, they are more likely to organize processes to determine the set of choices. Traditionally, an information system (IS) is viewed as the facilitator for opportunity exploitation when a new business model is assumed to be fully formulated; however, when the business model is not fully formulated, the role of the IS as the facilitator for opportunity discovery has been greatly overlooked. Using an in-depth case study of a large enterprise that is designing its next business model, we find that an IS can be used to facilitate opportunity discovery in formulating the narrative and numeric logics of a new business model and can facilitate opportunity exploitation in reconfiguring IS resources

Serum albumin and hemoglobin are associated with physical function in community-living older persons in Singapore

10.1007/s12603-011-0120-7Journal of Nutrition, Health and Aging1510877-88

Changes in facial fat in lipodystrophy, wasting and weight gain measured by magnetic resonance imaging

Background: Changes in facial fat occurring over time in patients with HIV-related lipoatrophy have not been properly quantified. We aimed to define the longitudinal changes in facial fat compartments in patients with lipoatrophy and to compare these with changes accompanying wasting or weight gain. Method: Facial MRI scans were performed at baseline and repeated after a median of 10 months in 24 patients, of whom 12 had moderate to severe lipodystrophy continuing antiretroviral therapy, 5 lost weight, and 7 gained weight (more than 10% weight change). Results: Superficial facial fat decreased by a median of 5.2 mL (p = .03) in patients with lipoatrophy, and 8 of 12 individuals showed more than 15% decrease (all of whom were taking stavudine). The decrease was mainly cheek fat. Superficial facial fat decreased by 6.0 mL in patients with weight loss (p = .04) and increased by 20.2 mL (p = .02) in patients with weight gain, and changes occurred in cheek fat, temporal fat, and masseter muscle and temporalis muscle compartments. Conclusion: MRI can detect substantial ongoing changes in facial fat in patients with facial lipoatrophy. A characteristic pattern of compartmental change distinguishes lipoatrophy from wasting and weight recovery. MRI should be considered for use in clinical trials of interventions to prevent or treat lipoatrophy and may be useful for documenting changes in individual patients during clinical follow-up. Changes in facial fat occurring over time in patients with HIV-related lipoatrophy have not been properly quantified. We aimed to define the longitudinal changes in facial fat compartments in patients with lipoatrophy and to compare these with changes accompanying wasting or weight gain. Facial MRI scans were performed at baseline and repeated after a median of 10 months in 24 patients, of whom 12 had moderate to severe lipodystrophy continuing antiretroviral therapy, 5 lost weight, and 7 gained weight (more than 10% weight change). Superficial facial fat decreased by a median of 5.2 mL (p = .03) in patients with lipoatrophy, and 8 of 12 individuals showed more than 15% decrease (all of whom were taking stavudine). The decrease was mainly cheek fat. Superficial facial fat decreased by 6.0 mL in patients with weight loss (p = .04) and increased by 20.2 mL (p = .02) in patients with weight gain, and changes occurred in cheek fat, temporal fat, and masseter muscle and temporalis muscle compartments. MRI can detect substantial ongoing changes in facial fat in patients with facial lipoatrophy. A characteristic pattern of compartmental change distinguishes lipoatrophy from wasting and weight recovery. MRI should be considered for use in clinical trials of interventions to prevent or treat lipoatrophy and may be useful for documenting changes in individual patients during clinical follow-up

Associations of hippocampal subfields in the progression of cognitive decline related to Parkinson's disease.

OBJECTIVE: Hippocampal atrophy has been associated with mild cognitive impairment (MCI) in Parkinson's disease (PD). However, literature on how hippocampal atrophy affects the pathophysiology of cognitive impairment in PD has been limited. Previous studies assessed the hippocampus as an entire entity instead of their individual subregions. We studied the progression of cognitive status in PD subjects over 18 in relation to hippocampal subfields atrophy. METHODS: 65 PD subjects were included. Using the MDS task force criteria, PD subjects were classified as either having no cognitive impairment (PD-NCI) or PD-MCI. We extended the study by investigating the hippocampal subfields atrophy patterns in those who converted from PD-NCI to PD-MCI (PD-converters) compared to those who remained cognitively stable (PD-stable) over 18 months. Freesurfer 6.0 was used to perform the automated segmentation of the hippocampus into thirteen subregions. RESULTS: PD-MCI showed lower baseline volumes in the left fimbria, right CA1, and right HATA; and lower global cognition scores compared to PD-NCI. Baseline right CA1 was also correlated with baseline attention. Over 18 months, decline in volumes of CA2-3 and episodic memory were also seen in PD-converters compared to PD-stable. Baseline volumes of GC-DG, right CA4, left parasubiculum, and left HATA were predictive of the conversion from PD-NCI to PD-MCI. CONCLUSION: The findings from this study add to the anatomical knowledge of hippocampal subregions in PD, allowing us to understand the unique functional contribution of each subfield. Structural changes in the hippocampus subfields could be early biomarkers to detect cognitive impairment in PD

Singaporean caregivers’ experiences of placing a relative into long term care

Caregivers experience many difficulties and challenges with the process of providing care particularly at times of transition, such as when the care recipient moves into a nursing home. This qualitative study aims to understand caregiver experiences of this important process. Methods: Twelve interviews were conducted with caregivers with an older relative in a nursing home in Singapore. The resulting data was analysed through thematic analysis. Results: Five themes were identified: Filial and cultural expectations shape caregivers’ experience of pre-placement decisions and post-placement; View of the placement decision; Continued impact of caring; Engagement with the institution and Maintaining the relationship. Conclusions: Caregivers were found to place significant emphasis on cultural values, specifically on filial piety. This impacted their caregiving role prior to placement, when making the decision to place their relative into a nursing home and in their continued involvement after placement. Despite the changing role, the placement experience was fraught with persisting difficulties involving maintaining the relationship with the resident and developing a new relationship with the nursing home

Reduced Health-Related Quality of Life in Elders with Frailty: A Cross-Sectional Study of Community-Dwelling Elders in Taiwan

PURPOSE: Exploring the domains and degrees of health-related quality of life (HRQOL) that are affected by the frailty of elders will help clinicians understand the impact of frailty. This association has not been investigated in community-dwelling elders. Therefore, we examined the domains and degree of HRQOL of elders with frailty in the community in Taiwan. METHODS: A total of 933 subjects aged 65 years and over were recruited in 2009 from a metropolitan city in Taiwan. Using an adoption of the Fried criteria, frailty was defined by five components: shrinking, weakness, poor endurance and energy, slowness, and low physical activity level. HRQOL was assessed by the short form 36 (SF-36). The multiple linear regression model was used to test the independent effects of frailty on HRQOL. RESULTS: After multivariate adjustment, elders without frailty reported significantly better health than did the pre-frail and frail elders on all scales, and the pre-frail elders reported better health than did the frail elders for all scales except the scales of role limitation due to physical and emotional problems and the Mental Component Summary (MCS). The significantly negative differences between frail and robust elders ranged from 3.58 points for the MCS to 22.92 points for the physical functioning scale. The magnitude of the effects of frail components was largest for poor endurance and energy, and next was for slowness. The percentages of the variations of these 10 scales explained by all factors in the models ranged from 11.1% (scale of role limitation due to emotional problems) to 49.1% (scale of bodily pain). CONCLUSIONS: Our study demonstrates that the disabilities in physical health inherent in frailty are linked to a reduction in HRQOL. Such an association between clinical measures and a generic measure of the HRQOL may offer clinicians new information to understand frailty and to conceptualize it within the broader context of disability