Biotechnology and the African Farmer

Research and Development/Tech Change/Emerging Technologies,

Determination of Urban Thermal Characteristics on an Urban/Rural Land Cover Gradient Using Remotely Sensed Data

The transformation from natural to impervious surfaces in an urbanization process and the urban heat island (UHI) phenomenon is known to significantly compromise urban environmental quality and has been linked to climate change and associated impacts. Whereas the existence of UHI is common knowledge, the implication of urban land use land cover (LULC) gradient on intra-urban thermal characteristics is often poorly understood. A recent proliferation of remotely sensed datasets offer great potential in understanding the relationship  between urban LULCs and their respective thermal characteristics, a critical basis for urban environmental  management and designing climate change mitigation measures. This study explores the potential of  multispectral remotely sensed dataset in determining the influence of rural/urban LULC gradient on urban  thermal characteristics. A rectangular eleven band Landsat 8 image subset was delineated from the central  business district to the rural periphery and classified into most dominant LULCs and a corresponding Landsat 8 thermal layer used to determine the LULCs thermal characteristics. Digitized point data was used to  determine differences in land surface temperature (LST) over gradient's LULC types. Results showed that  there was varied contribution of LULCs to the LST. As expected, the density of built up surfaces and LST  decreased towards the city’s periphery while a decline in vegetation density from the periphery led to an  increase in LST. These results provide valuable insights into the value of remotely sensed datasets in  understanding the implication of intra-urban LULC gradient on LST characteristics. Specifically, the study  demonstrates the value of remotely sensed data as aids to sustainable urban environmental planning

Factors Influencing Farmers Participation in Smallholder Irrigation Schemes: The Case of Ntfonjeni Rural Development Area

Most Swazi households depend on rainfed agriculture for food production, which limits the output because of the unreliable rainfall in the country. To mitigate this, the government has invested in rehabilitation of irrigation schemes to reduce the dependence on rainfall. This study therefore determined the factors influencing participation of farmers in small holder irrigation schemes in Swaziland, using Ntfonjeni Rural Development Area (RDA), as a case study. A multistage sampling technique was used to select 96 farming households, 48 participants of local irrigation scheme and 48 non participants. Data was collected using questionnaires. Analysis involved descriptive statistics and probit model. The study revealed that the participation in small holder irrigation schemes is significantly influenced by households distance to the scheme, age and occupation of household head, farm size and access to credit and membership in other groups. Participation improves output and income for households.  Hence it is recommended that peasant farmers should be assisted with credit facilities as an incentive to participate in irrigation schemes. Key words: Participation, small scale irrigation schemes, Probit, Ntfonjeni, Swaziland

Are HIV-positive presumptive tuberculosis patients without tuberculosis getting the care they need in Zimbabwe?

SETTING: Emakhandeni Clinic provides decentralised and integrated tuberculosis (TB) and human immunodeficiency virus (HIV) care in Bulawayo, Zimbabwe. OBJECTIVES: To compare HIV care for presumptive TB patients with and without TB registered in 2013. DESIGN: Retrospective cohort study using routine programme data. RESULTS: Of 422 registered presumptive TB patients, 26% were already known to be HIV-positive. Among the remaining 315 patients, 255 (81%) were tested for HIV, of whom 190 (75%) tested HIV-positive. Of these, 26% were diagnosed with TB and 71% without TB (3% had no TB result recorded). For the 134 patients without TB, antiretroviral treatment (ART) eligibility data were recorded for 42 (31%); 95% of these were ART eligible. Initiation of cotrimoxazole preventive therapy (CPT) and ART was recorded for respectively 88% and 90% of HIV-positive patients with TB compared with respectively 40% and 38% of HIV-positive patients without TB (P < 0.001). CONCLUSION: Presumptive TB patients without TB had a high HIV positivity rate and, for those with available data, most were ART eligible. Unlike HIV-positive patients diagnosed with TB, CPT and ART uptake for these patients was poor. A 'test and treat' approach and better service linkages could be life-saving for these patients, especially in southern Africa, where there are high burdens of HIV and TB

Removal of manganese from solution using polyamide membrane

Abstract: The work demonstrates the performance of polyamide membrane in the removal of manganese ions from single salt aqueous solution simulating real acid mine drainage. The membrane was tested using a dead-end filtration cell with manganese sulphate was used to prepare a feed solution. The membrane flux and metal rejection was evaluated. Effect of operating parameters such as pH, initial feed concentration and pressure on membrane performance was investigated. The pressure was varied between 10 and 15 bar and it was observed that increasing the pressure increases the membrane flux. Acidic pH conditions contributed to the removal of the contaminate as Mn2+ ions are freely at low pH. The percentage rejection was found to be 63.5 to 77.6 % as concentration is increased from 290 ppm to 321 ppm for a feed solution. The membrane showed satisfactory results in removing metal ions from solution

Barriers and facilitators to infection prevention and control in a neonatal unit in Zimbabwe – a theory-driven qualitative study to inform design of a behaviour change intervention

BACKGROUND: Hospital-acquired infection (HAI) is an increasing cause of neonatal morbidity/mortality in low-income settings. Hospital staff behaviours (e.g. hand hygiene) are key contributors to HAI. Understanding the drivers of these can inform interventions to improve infection prevention and control (IPC). AIM: To explore barriers/facilitators to IPC in a neonatal unit in Harare, Zimbabwe. METHODS: Interviews were conducted with fifteen staff members of neonatal and maternity units alongside ethnographic observations. The interview guide and data analysis were informed by the COM-B (Capability, Opportunity, Motivation-Behaviour) model and explored individual, socio-cultural, and organisational barriers/facilitators to IPC. Potential interventions were identified using the Behaviour-Change Wheel. FINDINGS: Enablers within Capability included awareness of IPC, and within Motivation beliefs that IPC was crucial to one's role, and concerns about consequences of poor IPC. Staff were optimistic that IPC could improve, contingent upon resource availability (Opportunity). Barriers included: limited knowledge of guidelines, no formal feedback on performance (Capability), lack of resources (Opportunity), often leading to improvisation and poor habit formation. Further barriers included the unit's hierarchy e.g. low engagement of cleaners and mothers in IPC, and staff witnessing implementation of poor practices by other team members (Opportunity). Potential interventions could include role-modelling, engaging mothers and staff across cadres, audit and feedback and flexible protocols (adaptable to water/handrub availability). CONCLUSIONS: Most barriers to IPC fell within Opportunity, whilst most enablers fell under Capability and Motivation. Theory-based investigation provides basis for systematically identifying and developing interventions to address barriers and enablers to IPC in low-income settings

Formulation and acceptability of local nutrient-dense foods for young children: A formative study for the Child Health, Agriculture and Integrated Nutrition (CHAIN) Trial in rural Zimbabwe.

Stunting affects almost one-quarter of children globally, leading to reduced human capacity and increased long-term risk of chronic disease. Despite intensive infant and young child feeding (IYCF) interventions, many children do not meet their requirements for essential nutrients. This study aimed to assess the feasibility of implementing an IYCF intervention utilizing nutrient-dense powders from egg, biofortified sugar beans and Moringa oleifera leaf in rural Zimbabwe. A mixed-methods formative study was conducted comprising the following: (i) a recipe formulation trial, (ii) trials of improved practices to assess acceptability of the intervention, and (iii) a participatory message formulation process to develop counselling modules for the IYCF-plus intervention. Twenty-seven mother-baby pairs were recruited between November 2019 and April 2020. Key domains affecting IYCF practices that emerged were time, emotional and physical space, cultural and religious beliefs, indigenous knowledge systems and gender dynamics. Household observations and sensory evaluation indicated high acceptability of the new ingredients. Recipe formulation and participatory message formulation by participants instilled community ownership and served to demystify existing misconceptions about the new food products. Families noted the potential for intervention sustainability because the foods could be grown locally. Supplementing complementary foods with nutrient-dense local food ingredients as powders has the potential to sustainably address nutrient-gaps in the diets of young children living in rural lower- and middle-income countries. Comprehensive IYCF counselling utilizing a gender-lens approach, family support and indigenous knowledge systems or resources are key elements to support positive behaviour change in complementary feeding interventions

A correlational study of systemic blood pressure and intraocular pressure in a young South African adult population*

Increased blood pressure (BP) and raised intraocular pressure (IOP) are probably both common oc-currences among the South African population. If left untreated both conditions have detrimental complications. Previous cross-sectional studies suggested BP was positively related to IOP. This study therefore sets out to determine in a young South African adult population the correlation between systemic BP and IOP.  Systemic BP was measured using an electronic sphygmomanometer and IOP using a Goldman applanation tonometer. For all subjects, two averages were obtained fromthree measurements each of BP and IOP. Other clinical procedures such as uncompensated visual acuity (VA), pinhole and direct ophthalmoscopy were done to exclude underlying factors possiblyaffecting either BP or IOP before the commencement of the investigation. Two hundred (N = 200) subjects were included in the study and their ages ranged from 18 to 30 years with a mean of 21 ± 3.9 years. The correlation coefficients between average IOP and average systolic or diastolic BP respectively were 0.67 and 0.55. These weak positive correlations suggested that with an increase in BP there is a corresponding increase in IOP. Also, similar correlation between IOP and BP was found toexist amongst both males and females with systolic BP having a greater effect. This study validates the importance of evaluating either systemic BP or IOP amongst all patients seen by primary eye-care practitioners, and that such evaluations should form part of daily routine patient examination

Community-based antiretroviral therapy versus standard clinic-based services for HIV in South Africa and Uganda (DO ART): a randomised trial

Background: Community-based delivery of antiretroviral therapy (ART) for HIV, including ART initiation, clinical and laboratory monitoring, and refills, could reduce barriers to treatment and improve viral suppression, reducing the gap in access to care for individuals who have detectable HIV viral load, including men who are less likely than women to be virally suppressed. We aimed to test the effect of community-based ART delivery on viral suppression among people living with HIV not on ART. / Methods: We did a household-randomised, unblinded trial (DO ART) of delivery of ART in the community compared with the clinic in rural and peri-urban settings in KwaZulu-Natal, South Africa and the Sheema District, Uganda. After community-based HIV testing, people living with HIV were randomly assigned (1:1:1) with mobile phone software to community-based ART initiation with quarterly monitoring and ART refills through mobile vans; ART initiation at the clinic followed by mobile van monitoring and refills (hybrid approach); or standard clinic ART initiation and refills. The primary outcome was HIV viral suppression at 12 months. If the difference in viral suppression was not superior between study groups, an a-priori test for non-inferiority was done to test for a relative risk (RR) of more than 0·95. The cost per person virally suppressed was a co-primary outcome of the study. This study is registered with ClinicalTrials.gov, NCT02929992. / Findings: Between May 26, 2016, and March 28, 2019, of 2479 assessed for eligibility, 1315 people living with HIV and not on ART with detectable viral load at baseline were randomly assigned; 666 (51%) were men. Retention at the month 12 visit was 95% (n=1253). At 12 months, community-based ART increased viral suppression compared with the clinic group (306 [74%] vs 269 [63%], RR 1·18, 95% CI 1·07–1·29; psuperiority=0·0005) and the hybrid approach was non-inferior (282 [68%] vs 269 [63%], RR 1·08, 0·98–1·19; pnon-inferiority=0·0049). Community-based ART increased viral suppression among men (73%, RR 1·34, 95% CI 1·16–1·55; psuperiority<0·0001) as did the hybrid approach (66%, RR 1·19, 1·02–1·40; psuperiority=0·026), compared with clinic-based ART (54%). Viral suppression was similar for men (n=156 [73%]) and women (n=150 [75%]) in the community-based ART group. With efficient scale-up, community-based ART could cost US$275–452 per person reaching viral suppression. Community-based ART was considered safe, with few adverse events. / Interpretation: In high and medium HIV prevalence settings in South Africa and Uganda, community-based delivery of ART significantly increased viral suppression compared with clinic-based ART, particularly among men, eliminating disparities in viral suppression by gender. Community-based ART should be implemented and evaluated in different contexts for people with detectable viral load. / Funding: The Bill & Melinda Gates Foundation; the University of Washington and Fred Hutch Center for AIDS Research; the Wellcome Trust; the University of Washington Royalty Research Fund; and the University of Washington King K Holmes Endowed Professorship in STDs and AIDS