6,506 research outputs found
Role of topical magnesium in post-operative sore throat: A systematic review and meta-analysis of randomised controlled trials
Pharmaceutical patenting trends on drugs and lifestyle diseases: an analysis of Indian and global status
The Indian pharmaceutical sector is large and has the
potential of a global leader for low-priced high-quality
drugs. The new patent regulations had a strong impact
on the drug industry in India. There is a serious decline
in the number of pharma patents recently after compulsory
licensing for drugs was implemented in India.
While regulations are meant for reducing the prices of
essential drugs, there are investment-related issues
when a patent is subjected to voluntary licensing. The
present study focuses on three phases in pharmaceutical
patenting identified by analysing the major patent
databases and the potential shift in pharma patenting
sector from acute to lifestyle disease-based drugs. The
recent trend identified in the pharma patenting sector
in India is quite unusual and unreported so far
Patent Database: Their Importance in Prior Art Documentation and Patent Search
In knowledge based economies the nation’s economic status depends on the production, distribution and use of knowledge
and information. The recent trend in the economic growth of nations is mainly determined by innovative technological knowhow
of the individuals. Intellectual property has gained attention in this era of knowledge. The vast amount of data generated
through the application of intellectual assets is managed with the help of various in- silico tools. In recent days, the patent
databases have gained importance due to the detailed information available on the granted patent and other details, such as,
legal status of the patent applications, which are not available through any other literature search. This review paper attempts to
describe different types of patent databases available, their unique features, strengths, weakness and their major purpose. This
paper details the information on how to access a patent database, the relevance of patent information obtained from these
databases in prior art search, patent analysis, and the drawbacks present in these patent databases
Prevalence and Determinants of Domestic Accidents in a Rural Area of Kanchipuram District, Tamil Nadu
Accident is defined as, ‘‘an unintentional injury which is undesirable, incidental and unplanned event that could have been prevented under circumstances leading to the accident being recognized’’. Accidents are of different types and domestic accidents are a worldwide threat but have seen resurgence in rural India. The main purpose of this study was to determine the prevalence and determinants of domestic accidents in rural area of Tamil Nadu and educate the people to reduce its burden. Materials and method: A community based cross sectional study, using a pre designed and pretested questionnaire was done in a rural area of Kanchipuram district, Tamil Nadu from 4th January 2017 to 31st January 2017. Data was collected from 1560 adults of both sexes and those who were the permanent residents of the study area. History of accident/injury during the past 3 months was obtained to avoid the recall bias. Results: It was found that 11.8 %( n=184) of the total study participants had a history of some form of accident/injury during the past 3 months. Out of these 184 subjects, 56.5 %(n=104) had domestic accidents. It was found that 51 %( n=53) of the domestic accidents have occurred due to ‘Fall’. Maximum numbers of the domestic accidents (42.3%) have occurred while the study subjects were working. Conclusion: Domestic accidents similar to any other disease have their own natural history and a sound knowledge about various determinants is essential to plan and administer prevention and control measures, and thereby reduce their burden especially in rural population. Increased awareness about the determinants will reduce the burden of the domestic accidents as they don’t simply befall on us from fate or bad luck. Keywords: Domestic, Accidents, Injury, Fal
Simple FOPI tuning method for real - order time delay systems
Fractional-order controllers (FOC) can be more adequate to control systems with complex dynamics than integer-order controllers; however, how to obtain FOC is still being explored vigorously. This paper deals with a tuning approach for FOC with primary requirements of simplicity in technique and robustness. A simple analytical method to tune fractional-order proportional-integral (FOPI) controller for known system transfer functions is proposed. Study shows the simplicity and efficiency of the presented design method over some previously published approaches
Improved Lossy Image Compression with Priming and Spatially Adaptive Bit Rates for Recurrent Networks
We propose a method for lossy image compression based on recurrent,
convolutional neural networks that outperforms BPG (4:2:0 ), WebP, JPEG2000,
and JPEG as measured by MS-SSIM. We introduce three improvements over previous
research that lead to this state-of-the-art result. First, we show that
training with a pixel-wise loss weighted by SSIM increases reconstruction
quality according to several metrics. Second, we modify the recurrent
architecture to improve spatial diffusion, which allows the network to more
effectively capture and propagate image information through the network's
hidden state. Finally, in addition to lossless entropy coding, we use a
spatially adaptive bit allocation algorithm to more efficiently use the limited
number of bits to encode visually complex image regions. We evaluate our method
on the Kodak and Tecnick image sets and compare against standard codecs as well
recently published methods based on deep neural networks
- …