Pregnancy in unicornuate uterus without rudimentary horn: a case report

A unicornuate uterus is associated with numerous obstetric and gynaecological complications such as infertility, endometriosis, miscarriage, malpresentations, and intrauterine growth restriction. Around 2.3-13% of Mullerian duct anomalies present as unicornuate uterus. Management of unicornuate uterus is still uncertain and it leads to poorer pregnancy outcome. We present here a case of 26-year-old primigravida who presented to us with 40-weeks pregnancy associated with breech presentation. She was taken for elective caesarean section and intra-operatively she was found to have unicornuate uterus without rudimentary horn. Unicornuate uterus is associated with poor pregnancy outcome but a successful pregnancy is possible. Usual presentation of patients with unicornuate uterus is near their menarche and they have higher than usual gynaecological complications. Pregnancies in unicornuate uterus are prone to intra uterine growth restriction hence serial ultrasound should be done for regular fetal growth monitoring

Effect of obesity and metabolic syndrome on severity, quality of life, sleep quality and inflammatory markers in patients of asthma in India

Introduction: The study aimed to compare the effect of obesity with and without metabolic syndrome on asthma severity, quality of life, sleep quality, sleep disordered breathing and inflammatory markers as compared to non-obese asthma patients. Material and methods: 60 asthma patients recruited for the study were divided equally into non-obese (NOA), obese without metabolic syndrome (OANMS) and obese with metabolic syndrome (OAMS) groups. Study cohorts were assessed for severity of asthma, quality of life and quality of sleep using questionnaires and inflammatory markers (FENO, hs-CRP, IL-5, IL-6 and leptin). Institutional ethical committee approved the study. Results: The results suggests OAMS patients may be a subtype of asthmatics having significantly severe asthma (p < 0.05), poor quality of life (p < 0.05), high risk of OSA (p < 0.05), decreased lung volumes (FRC) (p < 0.05), higher levels of inflammatory markers (leptin and IL-6) (p < 0.05), and high incidence of sleep disordered breathing (p < 0.05) in comparison to NOA and OANMS patients. Conclusions: The present study has shown that obese asthmatics especially with metabolic syndrome represent a subtype of asthmatic population. Hence, the treatment of metabolic syndrome may be necessary in addition to asthma to achieve optimal control.  INTRODUCTION: The study aimed to compare the effect of obesity with and without metabolic syndrome on asthma severity, quality of life, sleep quality, sleep disordered breathing and inflammatory markers as compared to non-obese asthma patients. MATERIAL AND METHODS: 60 asthma patients recruited for the study were divided equally into non-obese (NOA), obese without metabolic syndrome (OANMS) and obese with metabolic syndrome (OAMS) groups. Study cohorts were assessed for severity of asthma, quality of life and quality of sleep using questionnaires and inflammatory markers (FENO, hs-CRP, IL-5, IL-6 and leptin). Institutional ethical committee approved the study. RESULTS: The results suggests OAMS patients may be a subtype of asthmatics having significantly severe asthma (p < 0.05), poor quality of life (p  < 0.05), high risk of OSA (p < 0.05), decreased lung volumes (FRC) (p < 0.05), higher levels of inflammatory markers (leptin and IL-6) (p  < 0.05), and high incidence of sleep disordered breathing (p < 0.05) in comparison to NOA and OANMS patients. CONCLUSIONS: The present study has shown that obese asthmatics especially with metabolic syndrome represent a subtype of asthmatic population. Hence, the treatment of metabolic syndrome may be necessary in addition to asthma to achieve optimal control.

A study of expressed emotion, perceived stress and socio-demographic profile in patients of dissociative disorder

Background: Dissociation is understood as one of coping mechanism to deal with intense stressors. Individuals vary widely in their subjective response to a similar stressful event depending on number of factors including their family and social support system. So, authors tried to study the expressed emotion in patients of dissociative disorder along with other socio-demographic factors and its relation with perceived stress.Methods: This cross-sectional descriptive study was done on 100 patients with primary diagnosis of dissociative disorder. Hamilton depression rating scale (HAM-D) was used to assess comorbid Depressive symptoms and Hamilton anxiety rating scale (HAM-A) was used to asses comorbid anxiety symptoms. Perceived stress scale (PSS) was used to assess the perception of stress. Family emotional involvement and criticism scale (FEICS) was used to measure perceived criticism (PC) and intensity of emotional involvement (EI).Results: Mean perceived stress in this study was 25.8. Mean score for perceived criticism (PC) was 16.5 and emotional involvement (EI) was 15.7. Both measures of expressed emotions were significantly higher in females and subjects belonging to joint families and rural area. In this study perceived stress by subjects was significantly (p=0.001) correlated to perceived criticism (Pearson r = 0.78) and emotional involvement (Pearson r = 0.77).Conclusions: High perceived criticism and emotion over involvement of family member was associated with perceived stress in dissociation patients

Significant perceived stressors in irritable bowel syndrome: a stress interventional module analysed

Background: Psychological stress is an important factor for the development of irritable bowel syndrome (IBS). More and more clinical and experimental evidences are showing that IBS is a combination of irritable bowel and irritable brain. As IBS is a stress sensitive disorder, its treatment should focus on managing stress and stress-induced responses.Methods: This is a hospital based longitudinal study. 72 patients fulfilling the Rome IV criteria for irritable bowel syndrome were enrolled into the study. Perceived stress was assessed using student stress dimension questionnaire (SSDQ) while IBS severity was assessed using IBS severity scoring system (IBS-SSS). The stress interventional module (SIM) consist of specific domain targeted psychological interventions given to the patients weekly based on the stress domain mapping. The effectiveness of these interventions on reducing stress as well as IBS severity was assessed at baseline, and weeks 2, 4 and 6 follow-ups.Results: Of the studied IBS patients, most had SPS in multiple life domains while familial and interpersonal domains were affected in 78%. Also, total stress load in form of mean cumulative stress load at baseline was 451.1 which decreased significantly to 274.4 over 6 weeks. This SIM brought about a reduction in mean irritable bowel syndrome severity score from 27.5 to 20.6 in 6 weeks. This reduction in IBS severity score overtime was significant (p=0.001).Conclusions: Patients of irritable bowel syndrome show significant stress in multiple domains of life, which require proper assessment and management. Authors propose that individual-specific interventions aimed at reducing stress in all psychosocial life domains are efficacious and should be an integral part of managing IBS

Bronchoscopy in immediate diagnosis of smear negative tuberculosis

Wstęp: Gruźlica jest poważnym problemem zdrowia publicznego. Prawie u 30% chorych na gruźlicę bezpośrednie badanie plwociny na prątki jest ujemne. Prowadzi to do niezamierzonych opóźnień w leczeniu tych przypadków. W niniejszym badaniu zaplanowano ocenę roli bronchoskopii w szybkim rozpoznaniu gruźlicy u tych chorych.Materiał i metody: Niniejsze badanie jest retrospektywną analizą 132 chorych z podejrzeniem gruźlicy, u których nie stwierdzono prątków w bezpośrednim badaniu plwociny i którzy zostali poddani bronchoskopii w okresie 2002–2013.Gruźlicę rozpoznawano na podstawie stwierdzenia prątków w wydzielinie oskrzelowej lub w płukaniu oskrzelowo-pęcherzykowym względnie w materiale uzyskanym z biopsji. Rozpoznawano również gruźlicę na podstawie stwierdzenia martwicy serowatej w materiale z biopsji.Wyniki: Wynik niniejszego badania wykazał, że w wyniku bronchoskopii było możliwe ustalenie rozpoznania w 68,2% przypadków, w których badanie plwociny było negatywne. Potwierdzenie uzyskano po stwierdzeniu prątków w wydzielinie oskrzelowej lub płukaniu oskrzelowo-pęcherzykowym w 51,5% przypadków a na podstawie badania materiału z biopsji w 16,5%.Wnioski: Wyniki niniejszego badania wskazują na ważne miejsce bronchoskopii w szybkiej diagnostyce gruźlicy u chorych z ujemnym bezpośrednim badaniem plwociny. Pozwala to na uniknięcie opóźnień w rozpoznawaniu gruźlicy i nas zybkie podjęcie odpowiedniego leczenia.Background: Tuberculosis is a major public health problem. Almost 30% of cases of tuberculosis are known to be sputum smear negative. There is a diagnostic dilemma in such cases leading to inadvertent delays in management of these cases. The present study was planned to assess the role of bronchoscopy in immediate diagnosis of smear negative pulmonary tuberculosis.Material and methods: The present study is a retrospective analysis of 132 sputum smear negative tuberculosis suspects who underwent bronchoscopic evaluation during the period 2002–2013. The diagnosis of tuberculosis was based on the finding of bacilli in aspirate or in tissue biopsy or the demonstration of caseous necrosis on tissue biopsy.Results: The present study showed that bronchoscopy could lead to immediate, accurate diagnosis in 68.2% of suspected smear negative cases. Bronchial aspirate and bronchoalveolar lavage alone were diagnostic in 51.5% of such cases while tissue biopsy added to the yield in another 16.5% cases.Conclusions: The results of the present study suggests an important place of bronchoscopy in immediate diagnosis of suspected smear negative tuberculosis, thus avoiding inadvertent delays in diagnosing and instituting appropriate treatment

Predicting the Volatility of Stock Markets and Measuring its Interaction with Macroeconomic Variables: Indian Evidence, Case Study of NIFTY and SENSEX

This paper investigates the effects of economic factors on Indi

Body image perception, eating attitude and influence of media among undergraduate students of medical college in Delhi: a cross sectional study

Background: Body image perception is being shaped by unrealistic ideals portrayed in the media. Body dissatisfaction is one of the most consistent and robust risk factors for eating disorders, low self-esteem, depression, and obesity. Therefore, the objective of the current study is to ascertain the body image perception, abnormal eating attitudes and the role of media among undergraduate students of a medical college in Delhi, India.Methods: Cross-sectional study on 370 undergraduate medical students of Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India selected using stratified random sampling. India. Students completed a self-administered questionnaire which consist of demographic information, perceived body image, Eating Attitudes test (EAT-26) to assess eating attitudes, Socio Cultural Attitude Towards Appearance Questionnaire 3(SATAQ-3) scale for the role of media on body image perception. Data was analyzed using SPSS v21.Results: A total of 370 students (57.6% males and 42.4% females) aged 17-30 years, mean age of 20.30 years±2.02(SD). Abnormal body image perception was seen in 35.4%, 21.1% had abnormal eating attitude (EAT-26≥20), 36.5%, 40.5% agreed to be influenced by models and athletic figures in media respectively, 42.2% accepted that media was their source of information regarding standards of attractiveness, 27.6% felt pressured to be attractive according to SATAQ-3. Males more than females had disordered eating attitudes and felt media pressure to achieve an ideal body image. Significant association was observed between age and perceived body image (p=0.033), gender and EAT-26 score (p=0.039), EAT 26 and perceived body image (p=0.006), general internalization of media and perceived body image (p=0.003), internalization-general, internalization-athlete, media as source of information and EAT-26 score (<0.001, 0.001, 0.003 respectively).Conclusions: The media should take more responsibility to not represent unrealistic ideals of body image concerning both males and females. Educational and preventive efforts at institutional levels should be made to promote a healthy body image and eating behaviours

A Method of Transformation for Generalized Hypergeometric Function 2F2

By employing an addition theorem for the confluent hypergeometric function, Paris R.B.[3], has obtained a Kummer-type transformation for a 2F2 (x) hypergeometric function with general parameters in the form of a sum of 2F2 (-x) functions. Recently, Choi Junesang and Rathie Arjun K.[1], has obtained the same result without using the addition theorem. The aim of this paper is to derive the result of Paris R.B.[3], with change in the general parameters without using the addition theorem in the line of Choi Junesang and Rathie Arjun K.[1]. Corresponding author E.mail:- [email protected], [email protected]

Some cases of reducible Generalized Hypergeometric Functions

In this paper we consider the integrals of Generalized hypergeometric function of three variables given by Saran Shanti [4] and obtained  functions of two variables of Horn’s list given in  ErdelyiA.[1]. Our results are also motivated by Singh Pooja &amp; Singh Prof. (Dr.) Harish [3]