An artificial neural network application on nuclear charge radii

The artificial neural networks (ANNs) have emerged with successful applications in nuclear physics as well as in many fields of science in recent years. In this paper, by using (ANNs), we have constructed a formula for the nuclear charge radii. Statistical modeling of nuclear charge radii by using ANNs has been seen as to be successful. Also, the charge radii, binding energies and two-neutron separation energies of Sn isotopes have been calculated by implementing of the new formula in Hartree-Fock-Bogoliubov (HFB) calculations. The results of the study shows that the new formula is useful for describing nuclear charge radii.Comment: 7 pages, 3 figure

An Object-Oriented Language-Database Integration Model: The Composition-Filters Approach

This paper introduces a new model, based on so-called object-composition filters, that uniformly integrates database-like features into an object-oriented language. The focus is on providing persistent dynamic data structures, data sharing, transactions, multiple views and associative access, integrated with the object-oriented paradigm. The main contribution is that the database-like features are part of this new object-oriented model, and therefore, are uniformly integrated with object-oriented features such as data abstraction, encapsulation, message passing and inheritance. This approach eliminates the problems associated with existing systems such as lack of reusability and extensibility for database operations, the violation of encapsulation, the need to define specific types such as sets, and the incapability to support multiple views. The model is illustrated through the object-oriented language Sina

In vitro inhibition of the paraoxonase from human serum with sulfonamide

This study was conducted to determine the in vitro effects of sulfonamide on human serum paraoxonase (PON1) activity. The enzyme was purified by two-step using ammonium sulfate precipitation and sepharose-4B-L-tyrosine-1-napthylamine hydrophobic interaction chromatography.Sulfonamide was an effective inhibitor on purified human serum PON1 activity for phenylacetate and paraoxon as substrates with IC50 values of 0.22 and 0.81 mM, respectively. The kinetics of interaction ofsulfonamide with the purified enzyme indicated a different inhibition pattern for two substrates. Sulfonamide showed a non-competitive inhibition with Ki  of 0.0037 ± 0.0009 mM for phenylacetate and competitive inhibition with Ki of 0.0057 ± 0.0002 mM for paraoxon

The Efficacy of Antibiotics in the Treatment of Chlamydia Trachomatis Infections during Pregnancy. A Systematic Review and a Meta-analysis.

open access journalChlamydia trachomatis infections encountered during pregnancy can lead to many complications for both mother and neonate if left untreated. A systematic review and a meta-analysis were conducted to analyse the efficacy of antibiotic treatment infection during pregnancy that established the most effective antibiotic to treat Chlamydia trachomatis infections during pregnancy. PubMed and Cochrane Library were searched to the end of 2019. Randomised control trials that aligned with inclusion criteria of relevant antibiotics Azithromycin, Erythromycin, Clindamycin and Amoxicillin during Pregnancy was included. A systematic review and meta-analysis were used to calculate pooled (i) success of treatment for each antibiotic in several trials and (ii) the total adverse side effects for each drug encountered in several trials. Randomised controlled trials (RCTs) selected included 1917 pregnant patients with Chlamydia infections, and 851 have completed follow up assessments. Data from three RCTs observed a higher success of treatment for Azithromycin versus Erythromycin, fixed effect model, odds ratio (OR) = 0.67, 95% confidence interval (CI), 0.32-1.80. Data from three RCTs observed a higher success of treatment for Clindamycin versus Erythromycin OR = 2.43 95%, CI:2.00-2.60. Data from two RCTs showed a higher success of treatment for Amoxicillin versus Erythromycin OR = 3.74, 95%, CI:0.68-13.66. Analysis established that Erythromycin resulted in the most adverse side effects. Azithromycin was determined as the most effective antibiotic to treat C. trachomatis infections during pregnancy due to the high success of treatment. Clindamycin is capable of eradicating C. trachomatis infections in pregnancy and can be considered a secondary antibiotic treatment with fewer incidences of adverse side effects and high levels of successful treatment of the infection, however, due to a lack of studies more analysis will be required to confirm the efficacy of Clindamycin

Electrical Muscle Rehabilitation Apparatus Using a Optocoupler and Mega-Microcontroller

Muscle atrophy is a prevalent issue observed in individuals who experience immobility or restricted mobility as a result of accidents or illnesses. Physical therapy and exercise, often employed interventions for muscle atrophy, may occasionally lack applicability. The utilization of muscle electrical stimulation has demonstrated potential as a viable therapeutic option; however, further investigation is important to optimize its effectiveness and ensure its safety.  This study investigates the possible advantages of implementing electrical muscle stimulation (EMS) and explores the utilization of a transformer, optocouplers, and MOSFET (Metal-Oxide-Semiconductor Field-Effect Transistor) to enhance the efficacy of a high-capacity microcontroller-based EMS device. The issue of malfunctioning power transistors was successfully addressed through the implementation of an optocoupler-MOSFET circuit as a replacement for the power transistor. The findings of this investigation indicate that a direct electrical linkage between the signal-generating circuit and the transformer input is absent. The aforementioned features serve to ensure the safeguarding of the microcontroller circuit, establish electrical isolation between different stages of the system, and enhance the overall reliability of the EMS-designed system. The proposed framework introduces a novel technique that demonstrates a deliberate and considered approach when compared to existing studies in the field