Helicobacter pylori Seropositivity and Stool Antigen in Patients With Hyperemesis Gravidarum

The objective of this paper is to investigate whether Helicobacter pylori is an etiologic factor in hyperemesis gravidarum. Thirty one patients with hyperemesis gravidarum and twenty nine pregnant controls without hyperemesis gravidarum were included in this prospective study. All pregnant women were examined both for Helicobacter pylori serum immunoglobulin G antibodies (HpIgG Ab), showing chronic infection, and Helicobacter pylori stool antigens (HpSA), showing active gastrointestinal colonization. Chi-square and Student t tests were used accordingly for statistical analysis. Helicobacter pylori seropositivity was 67.7% in the patients with hyperemesis gravidarum and 79.3% in the control group (χ(2) = 1.02, P = .31). HpSA was detected in 22.6% of patients with hyperemesis gravidarum, whereas 6.9% of patients in the control group. The difference was not statistically significant (χ(2) = 2.89, P = .08). In this study, no relation was found between Helicobacter pylori and hyperemesis gravidarum. The low social status of women in both groups could be one of the reasons for the high prevalence of Hp infection

EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI) : Study protocol for a multicentre, observational trial

More than 300 million surgical procedures are performed each year. Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term outcomes. However, there is a large variation in the incidence of reported AKI rates. The establishment of an accurate epidemiology of surgery-associated AKI is important for healthcare policy, quality initiatives, clinical trials, as well as for improving guidelines. The objective of the Epidemiology of Surgery-associated Acute Kidney Injury (EPIS-AKI) trial is to prospectively evaluate the epidemiology of AKI after major surgery using the latest Kidney Disease: Improving Global Outcomes (KDIGO) consensus definition of AKI. EPIS-AKI is an international prospective, observational, multicentre cohort study including 10 000 patients undergoing major surgery who are subsequently admitted to the ICU or a similar high dependency unit. The primary endpoint is the incidence of AKI within 72 hours after surgery according to the KDIGO criteria. Secondary endpoints include use of renal replacement therapy (RRT), mortality during ICU and hospital stay, length of ICU and hospital stay and major adverse kidney events (combined endpoint consisting of persistent renal dysfunction, RRT and mortality) at day 90. Further, we will evaluate preoperative and intraoperative risk factors affecting the incidence of postoperative AKI. In an add-on analysis, we will assess urinary biomarkers for early detection of AKI. EPIS-AKI has been approved by the leading Ethics Committee of the Medical Council North Rhine-Westphalia, of the Westphalian Wilhelms-University Münster and the corresponding Ethics Committee at each participating site. Results will be disseminated widely and published in peer-reviewed journals, presented at conferences and used to design further AKI-related trials. Trial registration number NCT04165369

FOREIGN EXPERT REPORTS IN THE REPUBLIC PERIOD EDUCATION SYSTEM (1924-1960)

Cumhuriyet ilanından sonra devleti oluşturan bütün kurumlarda birçok yeni düzenlemelere ve bunun sonucu olarak değişmelere gidilmiştir. Modern toplumlar için bir kalkınma problemi olan eğitim kurumları ve bu kurumlardaki sistemde bu düzenlemeler ve değişmelerden fazlasıyla nasibini almıştır. nasibini almıştır. Eğitim ile ilgili düzenlemeler yapılırken milli devlet politikalarının yanı sıra emsal ülkelerin eğitim sistemi de örnek alınmıştır. Bunun sonucu olarak çeşitli ülkelerden ülkemize 1924'den başlayarak gerek resmi davet yoluyla gerekse gayri resmi olarak yabancı uzmanlar getirtilip eğitim sistemimiz için raporlar tutmaları istenmiştir. Her ne kadar İnönü döneminde bu süreç kesintiye uğrasa dan 1924-1960 yılları arası Türk eğitiminde yabancı uzmanların etkisi daha fazla hissedilmiştir. Ülkemize gelen yabancı eğitim uzmanları 1924-1950 döneminde ABD ve değişik Avrupa ülkelerinden gelirken, 1950'de başlayan Demokrat Parti döneminde ülkemize gelen yabancı uzmanların sadece ABD'li olması dikkat çekicidir. Özellikle bu durum üzerinden Demokrat Parti'ye muhalif çevrelerce ciddi eleştiriler yöneltildiği görülmektedir. Ancak yabancı uzmanlar konusunda ABD'ye yönelişin sebebi dönemin siyasi durumu, küresel güç dengeleri, Türkiye'nin uluslararası lobi ihtiyacından ötürü NATO ya girmesi ve ABD ile doğal müttefik olması olarak gösterilmektedir. Araştırmamızın amacı yabancı uzmanların eğitim sistemimiz hakkında tuttuğu raporların nitel olarak yeterliliklerini saptamak, olumlu ve olumsuz yönlerini ortaya koymaktır. Bunun için hazırladıkları raporlara ulaşılmış ve objektif bir açıdan değerlendirmeye tâbi tutulmuşturAfter the decleration of The Republic, there were many regularitions over the all institutions which had formed the state and, with the result of these, some changes education foundations which are a development problem for modern societies and the system in these foundations were highly effected by these regularitions and changes. While regulations related to the education are being done, the educational system of precedent countries are taken as an example as well as national government policies,too. Consequently, foreign experts from diffrent countries had been imported either via official invitation or non official way since the beginning of 1924, and wanted them to report our educational system. Altought this period was interupted between 1924-1960 years during the İnönü management ,the impact of the foreign expert was felt higly. It is remarkable that foreign education experts came to our country during the period when Democratic Party began in 1950 were only from the United States of America while foreign education experts coming to our country during the period 1924-1950 came from the United States and various European countries. It is observed serious criticisms were directed on this situation to Democratic Party by dissident circles. However, it is shown that the reasons for turning to the U.S. on foreign experts were the political situation of the period, the global balances of power, that Turkey joined due to Turkey's international lobby needs, that Turkey was a natural ally with the U.S durin this period. The aim of our research is to determine the qualification of the foreign experts reports as qualitative, to bring out the reports’ positive and negative aspects. Therefore, the reports have been detected and taken into evalution obtectivel

Investigate the relationship between the microbiota awareness in first trimester and high risk pregnancy in Turkish women: cross-sectional study

Abstract Background It is suggested that pregnancy risks may be related to microbial dysbiosis, and it is known that knowledge on this subject is reflected in behaviors. The purpose of this study was to investigate whether microbiota awareness in the first trimester of pregnancy is associated with pregnancy-related risks. Methods Within the scope of the study, the microbiota awareness scale was administered to 426 individuals in the first trimester of pregnancy, and information on any diagnosis related to high-risk pregnancy, gestational age, birth weight, and birth height of the newborn was obtained from their file records. Results The mean total microbiota awareness score of individuals was 61.38 ± 11.00 (26.00–91.00). The microbiota awareness score (56.85 ± 11.65) was found to be lower in individuals diagnosed with high-risk pregnancy (p < 0.05) than in healthy subjects (63.64 ± 9.94). Moreover, in individuals with high-risk pregnancies, a positive correlation was found between the microbiota awareness score and newborn birth weight and height (p < 0.05). Conclusion The poor microbiota awareness level in pregnant women is associated with high-risk pregnancy and neonatal growth status

Harlequin Ichtyosis: A Case Report

Harlequin ichthyosis is a severe and usually fatal congenital keratinization disorder. Although it has many characteristic findings on prenatal ultrasound such as a wide gaping mouth, intrauterine growth retardation, short limbs, joint contractures, edema of the hands and feet and cloudy amniotic fluid, most of the time it is diagnosed at birth. In this case report we summarize a patient who delivered a baby with Harlequin ichthyosis