MOESM2 of Oestrous cycle-dependent equine uterine immune response to induced infectious endometritis

Additional file 2. Statistical results for gene expression levels of all analysed genes. ANOVA, Bonferroni and interaction model results for the pathogen recognition receptors TLR2, TLR4, NLRC5, the chemokines CCL2, CXCL9, CXCL10, CXCL11, the tissue inhibitor of metallopeptidases (TIMP1) and the antimicrobial peptides lysozyme, lipocalin (LCN2), lactoferrin, uteroferrin, secretory leukoprotease inhibitor (SLPI), uterocalin P19, secreted phospholipase A2 (sPLA2) and equine β-defensin 1 (EBD1)

Anatomic location of dog bite wounds according to age group.

<p>Data is derived from victims attending three hospitals (Jigme Dorji Wangchuk National Referral hospital, Phuentsholing General hospital, Gelephu Regional Referral hospital) in Bhutan, 2009–2010 (the number in the figure indicates the number of bite victims). Age was categorized into the two groups indicated.</p

Decision tree model outlining the probability of rabies deaths.

<p>The model is adapted from Cleaveland et al., 2002 (reference number 11). Probabilities (P1–P10) are defined in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0001391#pntd-0001391-t004" target="_blank">Table 4</a> and described in the <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0001391#s2" target="_blank">methods</a> section. The probability calculated represents the probability of death following the bite of a suspect rabid dog.</p

Annual predicted death counts and incidence rate from rabies for different age groups in Phuentsholing and Gelephu areas of south Bhutan, calculated using the decision tree model.

<p>Annual predicted death counts and incidence rate from rabies for different age groups in Phuentsholing and Gelephu areas of south Bhutan, calculated using the decision tree model.</p

Standardized morbidity ratio (SMR) of reported dog bite incidents according to gender and age of victims in three hospital catchment areas (Jigme Dorji Wangchuk National Referral hospital, Phuentsholing General hospital, Gelephu Regional Referral hospital) in Bhutan, 2009–2010.

<p>N = number of reported dog bite victims in each group.</p><p>*SMR >1 means that they are more likely to report bites than expected, a value <1 means that they are less likely to report bites than expected and a value of 1 means that they are equally likely to reported than expected. Children in age group 5–9 are 2.3 times more likely to report dog bites than expected comparing to other age groups.</p

Annual incidence of dog bites/100,000 population classified by age and gender.

<p>Data is based on a survey of dog bite victims attending three hospitals (Jigme Dorji Wangchuk National Referral hospital, Phuentsholing General hospital, Gelephu Regional Referral hospital) in Bhutan, 2009–2010.</p

Model parameters, probability distributions and data sources used in the prediction of human deaths from rabies in Phuentsholing and Gelephu areas of south Bhutan from dog bite survey data.

<p>Model parameters, probability distributions and data sources used in the prediction of human deaths from rabies in Phuentsholing and Gelephu areas of south Bhutan from dog bite survey data.</p

Distribution of bite injuries on the body according to age group of dog bite patients in Phuentsholing and Gelephu hospital areas of south Bhutan.

<p>In the case of multiple bites, the site of the most severe bite is given. The row proportions (point estimate) are calculated for each group.</p

Anatomic location and severity of dog bite wounds.

<p>Data is derived from victims attending three hospitals (Jigme Dorji Wangchuk National Referral hospital, Phuentsholing General hospital, Gelephu Regional Referral hospital) in Bhutan, 2009–2010 (the number in the figure indicates the number of bite victims).</p

Comparison of occupation and other responses to a questionnaire of dog bite victims attending three hospitals (Jigme Dorji Wangchuk National Referral hospital, Phuentsholing General hospital, Gelephu Regional Referral hospital) in Bhutan, 2009–2010.

<p>Comparison of occupation and other responses to a questionnaire of dog bite victims attending three hospitals (Jigme Dorji Wangchuk National Referral hospital, Phuentsholing General hospital, Gelephu Regional Referral hospital) in Bhutan, 2009–2010.</p