42 research outputs found

    Hydraulic Characteristics of Rills

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    Rill density and rill flow rates were determined during rainfall simulation tests conducted at 11 sites located throughout the eastern United States. A mean rill density of 1.0 rills/m was found for the study locations. From measurements of the relative distribution of flow rates, a procedure is identified for partitioning flow between individual rills. Regression equations were developed for relating rill width and hydraulic roughness coefficients to flow rate. Equations were also derived for predicting mean flow velocity from visually determined measurements of advance velocity. Information reported in this study can be used to estimate hydraulic characteristics of rills

    A Controlled Evaluation of Devotional Meditation and Progressive Muscle Relaxation

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    The present study was conducted to determine the effects of devotional meditation (DM), defined as a period of prayer and quiet reading and pondering of biblical material, on physiological and psychological variables related to stress. It was hypothesized that religious persons engaging in DM experience physiological and psychological changes similar to those reported for persons using progressive relaxation (PR) exercises. Thirty-six participants, equally divided by sex into 3 groups: DM, PR, and a Wait List Control, underwent extensive psychophysiological assessment prior to and following a systematic introductio to either DM or PR. The hypothesis that DM could generate positive physiological and psychological effects similar to PR was partially confirmed. The results of the study are discussed in terms of the unique spiritual resources inherent among a Christian population that might foster physiological and psychological relaxation

    Conceptualising spaced learning in health professions education: A scoping review

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    Objectives To investigate the definitions and applications of 'spaced learning' and to propose future directions for advancing its study and practice in health professions education. Method The authors searched five online databases for articles published on spaced learning in health professions education prior to February 2018. Two researchers independently screened articles for eligibility with set inclusion criteria. They extracted and analysed key data using both quantitative and qualitative methods. Results Of the 2972 records retrieved, 120 articles were included in the review. More than 90% of these articles were published in the last 10 years. The definition of spaced learning varied widely and was often not theoretically grounded. Spaced learning was applied in distinct contexts, including online learning, simulation training and classroom settings. There was a large variety of spacing formats, ranging from dispersion of information or practice on a single day, to intervals lasting several months. Generally, spaced learning was implemented in practice or testing phases and rarely during teaching. Conclusions Spaced learning is infrequently and poorly defined in the health professions education literature. We propose a comprehensive definition of spaced learning and emphasise that detailed descriptions of spacing formats are needed in future research to facilitate the operationalisation of spaced learning research and practice in health professions education.Cardiolog

    Semaphorin-1a Is Required for Aedes aegypti Embryonic Nerve Cord Development

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    Although mosquito genome projects have uncovered orthologues of many known developmental regulatory genes, extremely little is known about mosquito development. In this study, the role of semaphorin-1a (sema1a) was investigated during vector mosquito embryonic ventral nerve cord development. Expression of sema1a and the plexin A (plexA) receptor are detected in the embryonic ventral nerve cords of Aedes aegypti (dengue vector) and Anopheles gambiae (malaria vector), suggesting that Sema1a signaling may regulate mosquito nervous system development. Analysis of sema1a function was investigated through siRNA-mediated knockdown in A. aegypti embryos. Knockdown of sema1a during A. aegypti development results in a number of nerve cord phenotypes, including thinning, breakage, and occasional fusion of the longitudinal connectives, thin or absent commissures, and general distortion of the nerve cord. Although analysis of Drosophila melanogaster sema1a loss-of-function mutants uncovered many similar phenotypes, aspects of the longitudinal phenotypes differed between D. melanogaster and A. aegypti. The results of this investigation suggest that Sema1a is required for development of the insect ventral nerve cord, but that the developmental roles of this guidance molecule have diverged in dipteran insects

    siRNA-Mediated Gene Targeting in Aedes aegypti Embryos Reveals That Frazzled Regulates Vector Mosquito CNS Development

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    Although mosquito genome projects uncovered orthologues of many known developmental regulatory genes, extremely little is known about the development of vector mosquitoes. Here, we investigate the role of the Netrin receptor frazzled (fra) during embryonic nerve cord development of two vector mosquito species. Fra expression is detected in neurons just prior to and during axonogenesis in the embryonic ventral nerve cord of Aedes aegypti (dengue vector) and Anopheles gambiae (malaria vector). Analysis of fra function was investigated through siRNA-mediated knockdown in Ae. aegypti embryos. Confirmation of fra knockdown, which was maintained throughout embryogenesis, indicated that microinjection of siRNA is an effective method for studying gene function in Ae. aegypti embryos. Loss of fra during Ae. aegypti development results in thin and missing commissural axons. These defects are qualitatively similar to those observed in Dr. melanogaster fra null mutants. However, the Aa. aegypti knockdown phenotype is stronger and bears resemblance to the Drosophila commissureless mutant phenotype. The results of this investigation, the first targeted knockdown of a gene during vector mosquito embryogenesis, suggest that although Fra plays a critical role during development of the Ae. aegypti ventral nerve cord, mechanisms regulating embryonic commissural axon guidance have evolved in distantly related insects

    Comparative Genomic Analysis of Drosophila melanogaster and Vector Mosquito Developmental Genes

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    Genome sequencing projects have presented the opportunity for analysis of developmental genes in three vector mosquito species: Aedes aegypti, Culex quinquefasciatus, and Anopheles gambiae. A comparative genomic analysis of developmental genes in Drosophila melanogaster and these three important vectors of human disease was performed in this investigation. While the study was comprehensive, special emphasis centered on genes that 1) are components of developmental signaling pathways, 2) regulate fundamental developmental processes, 3) are critical for the development of tissues of vector importance, 4) function in developmental processes known to have diverged within insects, and 5) encode microRNAs (miRNAs) that regulate developmental transcripts in Drosophila. While most fruit fly developmental genes are conserved in the three vector mosquito species, several genes known to be critical for Drosophila development were not identified in one or more mosquito genomes. In other cases, mosquito lineage-specific gene gains with respect to D. melanogaster were noted. Sequence analyses also revealed that numerous repetitive sequences are a common structural feature of Drosophila and mosquito developmental genes. Finally, analysis of predicted miRNA binding sites in fruit fly and mosquito developmental genes suggests that the repertoire of developmental genes targeted by miRNAs is species-specific. The results of this study provide insight into the evolution of developmental genes and processes in dipterans and other arthropods, serve as a resource for those pursuing analysis of mosquito development, and will promote the design and refinement of functional analysis experiments

    Grazing and Haying Effects on Runoff and Erosion From a Former Conservation Reserve Program Site

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    Grazing and haying effects on runoff and erosion from a former Conservation Reserve Program (CRP) site near Streeter, North Dakota, were determined. Treatments included undisturbed CRP, twice-over rotational grazing, season-long grazing, haying, and burning. Runoff and erosion were measured from simulated rainfall which was applied to 3.7 x 10.7 m (12.0 X 35.1 ft) plots. Following an initial stabilization period, no significant difference in runoff or erosion was found between the season-long grazing and burned treatments. Use of the CRP site for grazing or haying resulted in a significant increase in runoff compared to leaving the area in an undisturbed condition. Similar amounts of erosion were measured from the twice-over rotational grazing, season-long grazing, and hayed treatments. If adequate canopy and basal cover is maintained, use of this CRP site for grazing or haying would not be expected to result in excessive erosion

    Critical Shear Stress and Critical Flow Rates for Initiation of Rilling

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    This study was conducted to identify critical shear stress and critical flow rates required to initiate rilling on selected sites. The data used in this investigation were collected from soils located throughout the USA where crop residues had been removed, and moldboard plowing and disking had occurred. Runoff and soil loss measurements were made on sites where simulated rainfall was applied to preformed rills. Multiple regression analyses were used to relate critical shear stress values and critical flow rates to selected soil properties. The soil-based regression equations were found to provide reliable estimates. Information identified in this study will improve our ability to understand and properly model upland runoff and erosion processes
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