Avaliação Da Percepção Háptica

7413

Applying a new version of the Brazilian-Portuguese UPSIT smell test in Brazil

Standardized olfactory tests are now available to quantitatively assess disorders of olfaction. A Brazilian-Portuguese version of the University of Pennsylvania Smell Identification Test (UPSIT) is currently being developed specifically for the Brazilian population. The most recent Brazilian-Portuguese version of the UPSIT (UPSIT-Br2) was administered to 88 Brazilian subjects who had no history of neurological or otorhinolaryngological disease. UPSIT-Br2 scores decreased with age, were lower in men than in women, and were lower in subjects with lower income. The degree to which the poorer performance of subjects with lower socio-economic status reflects lack of familiarity with test items is not known. Although this version of the UPSIT provides a sensitive and useful test of smell function for the Brazilian population, a revision of some test items is needed to achieve comparable norms to those found using the North American UPSIT in the United States

Diagnosing social anxiety in Parkinson’s disease: Characteristics and frequencies according to two diagnostic criteria

BACKGROUND: Studies found inconsistent frequencies of social anxiety disorder (SAD) in Parkinson’s disease (PD) (9.7%-50%). Previous reports did not test the impact of applying DSM-IV restrictive criteria that recommends the exclusion of secondary cases when diagnosing SAD in PD. OBJECTIVE: Our aim is to estimate the frequency of social anxiety according to DSM-IV criteria and according to an inclusive broader approach. Methods: One hundred and ten PD patients were assessed for the presence of SAD using SCID-I, diagnosis of social anxiety were determined according to two different criteria: following and not following DSM-IV recommendation for exclusion of cases though to be secondary to a general medical condition. RESULTS: SAD was present in 34 (31%) of patients, but 17 (15.5%) were secondary to a general medical condition. Patients with SAD were significantly younger, had earlier disease onset, had more severe PD symptoms, and were more frequently depressed. There was no difference in demographic and clinical features between primary and secondary SAD. DISCUSSION: We conclude that the use of different diagnostic criteria may have a massive impact in the estimation of frequency of SAD in PD

Tricks Of The Trade [pulo Do Gato]

[No abstract available]704245Hoch, W., McConville, J., Helms, S., Newsom-Davis, J., Melms, A., Vincent, A., Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies (2001) Nat Med, 7, pp. 365-368Leite, M.I., Jacob, S., Viegas, S., IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis (2008) Brain, 131, pp. 1940-1952Barber, P.A., Anderson, N.E., Vincent, A., Morvan's syndrome associated with voltage-gated K+ channel antibodies (2000) Neurology, 54, pp. 771-772Liguori, R., Vincent, A., Clover, L., Morvan's syndrome: Peripheral and central nervous system and cardiac involvement with antibodies to voltage-gated potassium channels (2001) Brain, 124, pp. 2417-2426Vincent, A., Buckley, C., Schott, J.M., Potassium channel antibody-associated encephalopathy: A potentially immunotherapy-responsive form of limbic encephalitis (2004) Brain, 127, pp. 701-712Irani, S.R., Alexander, S., Waters, P., Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia (2010) Brain, 133, pp. 2734-2748Hutchinson, M., Waters, P., McHugh, J., Progressive encephalomyelitis, rigidity, and myoclonus: A novel glycine receptor antibody (2008) Neurology, 71, pp. 1291-129

Um Guia Prático Sobre A Anatomia Do Rinencéfalo

7432933

Aplicando uma nova versão brasileira do UPSIT no Brasil

Standardized olfactory tests are now available to quantitatively assess disorders of olfaction. A Brazilian-Portuguese version of the University of Pennsylvania Smell Identification Test (UPSIT) is currently being developed specifically for the Brazilian population. The most recent Brazilian-Portuguese version of the UPSIT (UPSIT-Br2) was administered to 88 Brazilian subjects who had no history of neurological or otorhinolaryngological disease. UPSIT-Br2 scores decreased with age, were lower in men than in women, and were lower in subjects with lower income. The degree to which the poorer performance of subjects with lower socio-economic status reflects lack of familiarity with test items is not known. Although this version of the UPSIT provides a sensitive and useful test of smell function for the Brazilian population, a revision of some test items is needed to achieve comparable norms to those found using the North American UPSIT in the United States.Testes padronizados já estão disponíveis para testagem do olfato e uma versão em Português esta sendo desenvolvida para o University of Pennsylvania Smell Identification Test (UPSIT), especificamente para a população brasileira. A versão mais recente deste teste (chamada UPSIT-Br2) foi aplicada a 88 sujeitos brasileiros que não tinham história de qualquer problema neurológico ou otorrinolaringológico. Compatível com dados prévios da literatura, a performance no UPSIT-Br2 decaiu com a idade e foi inferior no genero masculino. Os resultados foram mais baixos em participantes de menor nível sócio-econômico e a relação deste achado com a falta de familiaridade para com os itens do teste não é conhecida. Apesar desta versão do UPSIT poder ser útil para o teste da função olfativa da população brasileira, a revisão de alguns itens se faz necessária para alcançar valores comparáveis aos dados normativos norte-americanos.Reta Lila Weston Trust for Medical Researc

Pisa syndrome in Parkinson's disease: a mobile or fixed deformity?

Although Pisa syndrome and scoliosis are sometimes used interchangeably to describe a laterally flexed postural deviation in Parkinson's disease (PD), the imaging findings of Pisa syndrome in PD have not been previously studied in detail

Is transcranial sonography useful to distinguish scans without evidence of dopaminergic deficit patients from Parkinson's disease?

BACKGROUND: Approximately 10% of patients clinically diagnosed with early Parkinson's disease (PD) subsequently have normal dopaminergic functional imaging. Transcranial sonography (TCS) has been shown to detect midbrain hyperechogenicity in approximately 90% of Parkinson's disease (PD) patients and 10% of the healthy population. The aim of this study was to investigate the prevalence of midbrain hyperechogenicity in patients with suspected parkinsonism and scans without evidence of dopaminergic deficit (SWEDD), in comparison to PD patients. METHODS: TCS was performed in 14 patients with SWEDD and 19 PD patients. RESULTS: There was a significantly increased area of echogenicity in the PD group (0.24 ± 0.06 cm(2) ), compared to the group of patients with SWEDD (0.13 ± 0.06 cm(2) ; P < 0.001). One (9.1%) of these patients, compared to 14 (82.5%) of the PD patients, was found to have hyperechogenicity (P < 0.001). CONCLUSIONS: We conclude that TCS is useful to distinguish PD patients from patients with suspected parkinsonism and SWEDD

PREDICT-PD: Identifying risk of Parkinson's disease in the community: methods and baseline results

To present methods and baseline results for an online screening tool to identify increased risk for Parkinson's disease (PD) in the UK population

Meta-Analysis of Early Nonmotor Features and Risk Factors for Parkinson Disease

"This is the peer reviewed version of the following article: Noyce, A. J., Bestwick, J. P., Silveira‐Moriyama, L. , Hawkes, C. H., Giovannoni, G. , Lees, A. J. and Schrag, A. (2012), Meta‐analysis of early nonmotor features and risk factors for Parkinson disease. Ann Neurol., 72: 893-901. doi:10.1002/ana.23687, which has been published in final form at [https://doi.org/10.1002/ana.23687 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.