4,168 research outputs found
An analysis of the phase space of Horava-Lifshitz cosmologies
Using the dynamical system approach, properties of cosmological models based
on the Horava-Lifshitz gravity are systematically studied. In particular, the
cosmological phase space of the Horava-Lifshitz model is characterized. The
analysis allows to compare some key physical consequences of the imposition (or
not) of detailed balance. A result of the investigation is that in the detailed
balance case one of the attractors in the theory corresponds to an oscillatory
behavior. Such oscillations can be associated to a bouncing universe, as
previously described by Brandenberger, and will prevent a possible evolution
towards a de Sitter universe. Other results obtained show that the cosmological
models generated by Horava-Lifshitz gravity without the detailed balance
assumption have indeed the potential to describe the transition between the
Friedmann and the dark energy eras. The whole analysis leads to the plausible
conclusion that a cosmology compatible with the present observations of the
universe can be achieved only if the detailed balance condition is broken.Comment: 12 pages, some typos corrected, some references adde
Role of Oxidative Stress in Transformation Induced by Metal Mixture
Metals are ubiquitous pollutants present as mixtures. In particular, mixture of arsenic-cadmium-lead is among the leading toxic agents detected in the environment. These metals have carcinogenic and cell-transforming potential. In this study, we used a two step cell transformation model, to determine the role of oxidative stress in transformation induced by a mixture of arsenic-cadmium-lead. Oxidative damage and antioxidant response were determined. Metal mixture treatment induces the increase of damage markers and the antioxidant response. Loss of cell viability and increased transforming potential were observed during the promotion phase. This finding correlated significantly with generation of reactive oxygen species. Cotreatment with N-acetyl-cysteine induces effect on the transforming capacity; while a diminution was found in initiation, in promotion phase a total block of the transforming capacity was observed. Our results suggest that oxidative stress generated by metal mixture plays an important role only in promotion phase promoting transforming capacity
Coupled reliability model of biodeterioration, chloride ingress and cracking for reinforced concrete structures
International audienceMaintaining and operating civil infrastructure systems has been recognized as a critical issue worldwide. Among all possible causes of safety reduction during the structural lifetime, deteriora- tion is particularly important. Structural deterioration is usually a slow time-dependent process controlled by safety and operation threshold specifications. This paper presents a model of RC deterioration by coupling biodeterioration (i.e., chemical, physical and mechanical action of live organisms), steel corrosion, and concrete cracking. The final purpose of the model is to compute the reduction of the concrete section and the area of steel reinforcement in order to assess the change of structural capacity with time. Given the uncertainties in both the parameters and the model, the probabilistic nature of loads, the material properties and the difussion process are taken into account to evaluate structural reliability. The model is illustrated with an example where the inelastic behavior of a pile subject to random loading is considered. The results of the analysis have shown that the effect of biodeterioration on the structural performance is significant and can cause an important reduction of its lifetime. On the whole, the paper states that modeling the effects of biodeterioration in RC structures should be included as part of infrastructure planning and design, especially, when they are located in aggressive environments
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