The Universality of Initial Conditions for Globular Cluster Formation

We investigate a simple model for globular cluster (GC) formation. We simulate the violent relaxation of initially homogeneous isothermal stellar spheres and show that it leads to the formation of clusters with radial density profiles that match the observed profiles of GCs. The best match is achieved for dynamically unevolved clusters. In this model, all the observed correlations between global GC parameters are accurately reproduced if one assumes that all the clusters initially had the same value of the stellar density and the velocity dispersion. This suggests that the gas which formed GCs had the same values of density and temperature throughout the universe.Comment: 12 pages, 4 figures, 1 table. Accepted for publication in ApJ Letter

The Dynamical Implications of Multiple Stellar Formation Events in Galactic Globular Clusters

Various galactic globular clusters display abundance anomalies that affect the morphology of their colour-magnitude diagrams. In this paper we consider the possibility of helium enhancement in the anomalous horizontal branch of NGC 2808. We examine the dynamics of a self-enrichment scenario in which an initial generation of stars with a top-heavy initial mass function enriches the interstellar medium with helium via the low-velocity ejecta of its asymptotic giant branch stars. This enriched medium then produces a second generation of stars which are themselves helium-enriched. We use a direct N-body approach to perform five simulations and conclude that such two-generation clusters are both possible and would not differ significantly from their single-generation counterparts on the basis of dynamics. We find, however, that the stellar populations of such clusters would differ from single-generation clusters with a standard initial mass function and in particular would be enhanced in white dwarf stars. We conclude, at least from the standpoint of dynamics, that two-generation globular clusters are feasible.Comment: 24 pages, 7 figures, 3 tables. Accepted for publication in Ap

Constraining global properties of the Draco dwarf spheroidal galaxy

By fitting a flexible stellar anisotropy model to the observed surface brightness and line-of-sight velocity dispersion profiles of Draco we derive a sequence of cosmologically plausible two-component (stars + dark matter) models for this galaxy. The models are consistent with all the available observations and can have either cuspy Navarro-Frenk-White or flat-cored dark matter density profiles. The dark matter halos either formed relatively recently (at z~2...7) and are massive (up to ~5x10^9 M_Sun), or formed before the end of the reionization of the universe (z~7...11) and are less massive (down to ~7x10^7 M_Sun). Our results thus support either of the two popular solutions of the "missing satellites" problem of Lambda cold dark matter cosmology - that dwarf spheroidals are either very massive, or very old. We carry out high-resolution simulations of the tidal evolution of our two-component Draco models in the potential of the Milky Way. The results of our simulations suggest that the observable properties of Draco have not been appreciably affected by the Galactic tides after 10 Gyr of evolution. We rule out Draco being a "tidal dwarf" - a tidally disrupted dwarf galaxy. Almost radial Draco orbits (with the pericentric distance <15 kpc) are also ruled out by our analysis. The case of a harmonic dark matter core can be consistent with observations only for a very limited choice of Draco orbits (with the apocentric-to-pericentric distances ratio of <2.5).Comment: 18 pages, 14 figures; accepted by Ap

Models of Individual Blue Stragglers

This chapter describes the current state of models of individual blue stragglers. Stellar collisions, binary mergers (or coalescence), and partial or ongoing mass transfer have all been studied in some detail. The products of stellar collisions retain memory of their parent stars and are not fully mixed. Very high initial rotation rates must be reduced by an unknown process to allow the stars to collapse to the main sequence. The more massive collision products have shorter lifetimes than normal stars of the same mass, while products between low mass stars are long-lived and look very much like normal stars of their mass. Mass transfer can result in a merger, or can produce another binary system with a blue straggler and the remnant of the original primary. The products of binary mass transfer cover a larger portion of the colour-magnitude diagram than collision products for two reasons: there are more possible configurations which produce blue stragglers, and there are differing contributions to the blended light of the system. The effects of rotation may be substantial in both collision and merger products, and could result in significant mixing unless angular momentum is lost shortly after the formation event. Surface abundances may provide ways to distinguish between the formation mechanisms, but care must be taking to model the various mixing mechanisms properly before drawing strong conclusions. Avenues for future work are outlined.Comment: Chapter 12, in Ecology of Blue Straggler Stars, H.M.J. Boffin, G. Carraro & G. Beccari (Eds), Astrophysics and Space Science Library, Springe

Quality of Life Explorer Prototype to Address Socio-economic Problems: A Design Science Approach

This study develops a visualization Proof of Concept that is aimed at improving the quality of life for the city in the South-Eastern part of US as a case study. Using design science research method, we create interactive visual maps called the quality of life explorer (QoLE) for improving the livelihood of residents of the city under study. We then used analytics techniques to customize the map and enhance its visualization and interactivity capabilities in a way that is simple to understand and use. Furthermore, the QoLE website has a built-in capability that allows report generation as well as increase interactivity of Map and data distribution tables. The outcome of this study will help the city authorities and residents to better visualize the data in a smarter and realistic way so that they can make informed decisions in redeveloping their city. More specifically, the study outcomes will help the City authorities and stakeholders integrate the disparate data into a centralized location for easy accessibility and use for decision making

Genetic maps of Saccharum officinarum L. and Saccharum robustum Brandes & Jew ex grassl.

Genetic analysis was performed in a population composed of 100 F1 individuals derived from a cross between a cultivated sugarcane (S. officinarum La Purple) and its proposed progenitor species (S. robustum "Mol 5829'). Various types (arbitrarily primed-PCR, RFLPs, and AFLPs) of single-dose DNA markers (SDMs) were used to construct genetic linkage maps to both species. The LA Purple map was composed of 341 SDMs, spanning 74 linkage groups and 1.881 cM, white the Mol 5829 map contained 301 SDMs, spanning 65 linkage gropus and 1,189 cM, Transmission genetics in these two species showed incomplete polysomy based on the detection of 15% of SDMs linked in repulsion in LA Purple and 13% of these in Mol 5829. Because of this incomplete polysomy, multiple-dose markers could not be mapped for lack of a genetic model for their segregation. Due to inclusion of RFLP anchor probes, conserved in related species, the resulting maps will serve as useful tools for breeding, ecology, evolution, and molecular biology studies within the Andropogoneae

Array comparative genomic hybridization screening in IVF significantly reduces number of embryos available for cryopreservation

Objective During IVF, non-transferred embryos are usually selected for cryopreservation on the basis of morphological criteria. This investigation evaluated an application for array comparative genomic hybridization (aCGH) in assessment of surplus embryos prior to cryopreservation. Methods First-time IVF patients undergoing elective single embryo transfer and having at least one extra non-transferred embryo suitable for cryopreservation were offered enrollment in the study. Patients were randomized into two groups: Patients in group A (n=55) had embryos assessed first by morphology and then by aCGH, performed on cells obtained from trophectoderm biopsy on post-fertilization day 5. Only euploid embryos were designated for cryopreservation. Patients in group B (n=48) had embryos assessed by morphology alone, with only good morphology embryos considered suitable for cryopreservation. Results Among biopsied embryos in group A (n=425), euploidy was confirmed in 226 (53.1%). After fresh single embryo transfer, 64 (28.3%) surplus euploid embryos were cryopreserved for 51 patients (92.7%). In group B, 389 good morphology blastocysts were identified and a single top quality blastocyst was selected for fresh transfer. All group B patients (48/48) had at least one blastocyst remaining for cryopreservation. A total of 157 (40.4%) blastocysts were frozen in this group, a significantly larger proportion than was cryopreserved in group A (p=0.017, by chi-squared analysis). Conclusion While aCGH and subsequent frozen embryo transfer are currently used to screen embryos, this is the first investigation to quantify the impact of aCGH specifically on embryo cryopreservation. Incorporation of aCGH screening significantly reduced the total number of cryopreserved blastocysts compared to when suitability for freezing was determined by morphology only. IVF patients should be counseled that the benefits of aCGH screening will likely come at the cost of sharply limiting the number of surplus embryos available for cryopreservation

Discovery of another peculiar radial distribution of Blue Stragglers in Globular Clusters: The case of 47 Tuc

We have used high resolution WFPC2-HST and wide field ground-based observations to construct a catalog of blue straggler stars (BSS) in the globular cluster 47 Tuc spanning the entire radial extent of the cluster. The BSS distribution is highly peaked in the cluster center, rapidly decreases at intermediate radii, and finally rises again at larger radii. The observed distribution closely resembles that discovered in M3 by Ferraro et al (1993,1997). To date, complete BSS surveys covering the full radial extent (HST in the center and wide field CCD ground based observations of the exterior) have been performed for only these two clusters. Both show a bimodal radial distribution, despite their different dynamical properties. BSS surveys covering the full spatial extent of more globular clusters are clearly required to determine how common bimodality is and what its consequence is for theories of BSS formation and cluster dynamics.Comment: 21 pages, 6 figures, accepted for pubblication in Ap

Discovery of Carbon/Oxygen depleted Blue Straggler Stars in 47 Tucanae: the chemical signature of a mass-transfer formation process

We use high-resolution spectra obtained with the ESO Very Large Telescope to measure surface abundance patterns of 43 Blue Stragglers stars (BSS) in 47 Tuc. We discovered that a sub-population of BSS shows a significant depletion of Carbon and Oxygen with respect to the dominant population. This evidence would suggest the presence of CNO burning products on the BSS surface coming from a deeply peeled parent star, as expected in the case of mass-transfer process. This is the first detection of a chemical signature clearly pointing to a specific BSS formation process in a globular cluster.Comment: Published on 2006, August 10, in ApJ 647, L5

Correlations from gadopentetate dimeglumine-enhanced magnetic resonance imaging after methotrexate chemotherapy for hemorrhagic placenta increta

OBJECTIVE: To describe pre- and post-methotrexate (MTX) therapy images from pelvic magnetic resonance imaging (MRI) with gadopentetate dimeglumine contrast following chemotherapy for post-partum hemorrhage secondary to placenta increta. MATERIAL AND METHOD: A 28-year-old Caucasian female presented 4 weeks post-partum complaining of intermittent vaginal bleeding. She underwent dilatation and curettage immediately after vaginal delivery for suspected retained placental tissue but 28 d after delivery, the serum β-hCG persisted at 156 IU/mL. Office transvaginal sonogram (4 mHz B-mode) was performed, followed by pelvic MRI using a 1.5 Tesla instrument after administration of gadolinium-based contrast agent. MTX was administered intramuscularly, and MRI was repeated four weeks later. RESULTS: While transvaginal sonogram suggested retained products of conception confined to the endometrial compartment, an irregular 53 × 34 × 28 mm heterogeneous intrauterine mass was noted on MRI to extend into the anterior myometrium, consistent with placenta increta. Vaginal bleeding diminished following MTX treatment, with complete discontinuation of bleeding achieved by ~20 d post-injection. MRI using identical technique one month later showed complete resolution of the uterine lesion. Serum β-hCG was <5 IU/mL. CONCLUSION: Reduction or elimination of risks associated with surgical management of placenta increta is important to preserve uterine function and reproductive potential. For selected hemodynamically stable patients, placenta increta may be treated non-operatively with MTX as described here. A satisfactory response to MTX can be ascertained by serum hCG measurements with pre- and post-treatment pelvic MRI with gadopentetate dimeglumine enhancement, which offers advantages over standard transvaginal sonography