5 research outputs found

    Minimum p-values from tests of association for the autosomal SNPs <sup>*</sup>.

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    <p><sup>*</sup>Genotypic tests of dominant, recessive, general, heterozygous advantage, and additive models, adjusted for HbS and ethnicity; in this analysis controls include uncomplicated malaria cases; the dashed line represents a p-value of 0.002.</p

    Single nucleotide polymorphisms.

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    <p>MinA = minor allele, MajA = major allele, MAF = overall minor allele frequency, HWE P is the Hardy-Weinberg p-value, OR = odds ratio, 95% Confidence interval (LCL, UCL), P = P-value; rs8176746 and rs8176719 are used to infer ABO blood groups; for X chromosome SNPs (rs3092945 (CD40), rs1126535 (CD40), rs1050829 (G6PD-376), rs1050828 (G6PD-202/A-), analyses are presented for separately for females (F) and males (M) and pooled to obtain overall results (Ov), NA not applicable; rs33950507, rs5743611, rs2814778, rs2227478, rs2535611 and rs1801274 did not pass quality control filters and are not presented.</p
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