1,297 research outputs found
Sources and directions of social support and life satisfaction among solitary Chinese older adults in Hong Kong: the mediating role of sense of loneliness
Based on survey data collected from 151 community-dwelling solitary Chinese older adults in Hong Kong, the present study used path analysis to examine the mediating role of sense of loneliness in the relationship between different sources and directions of social support and life satisfaction. The results showed that sense of loneliness mediated the effects of support from families, friends, and support for others on life satisfaction. In addition, a formal source of social support was not associated with life satisfaction among solitary older adults, although those with a more secure financial status had greater overall life satisfaction. These findings highlight the importance of enhancing awareness among social and health care service providers about the negative effects of insufficient social support on older adults’ sense of loneliness and life satisfaction. Family and friendship networks should be expanded for solitary older adults
Activity and expression of ADP-glucose pyrophosphorylase during rhizome formation in lotus (Nelumbo nucifera Gaertn.)
Additional file 7: Figure S6. Comparison of NnAGPS against AGPS of other species
Design of Interference Measurement System with Crystal
A kind of interference measurement system with crystal is designed, which is not influenced much by other factors such as vibration for the property of common path. For the distance measurement, the phase of fringes is calculated on the oblique incident holography to avoid effects of fringe curvature, backup and light fluctuation. But the measurement result is affected by the uniformity of the crystal, and another method of adjusting position based on normal incident holography is also discussed. B-splines function is used to calculate zero position in normal incident holography, which is fitted over the patch image around gray extreme points of the stripes obtained by gray projection. Experiment results show that combining the normal and oblique incident holography reduce the repeatability error of the system and improve the measurement precision effectively. DOI: http://dx.doi.org/10.11591/telkomnika.v11i3.230
1H NMR based metabolites analysis of murine melanoma cells and primary melanocytes
Melanoma is one of the most life-threatening skin cancer characterized by ineffective therapies and rising incidence. Here we applied 1H NMR to acquire details of metabolic rewiring between primary melanocytes and murine melanoma cells. A total of 29 metabolites were assigned and identified. The principal component analysis (PCA) illustrated a distinct separation along the first component. A constructed orthogonal partial least squares-discriminant (OPLS-DA) model obtained intrinsic variations as PCA analysis did. The corresponding S-plot and loading plot revealed some significant variations of metabolites in melanoma compared with the control group, including the obvious increases of isoleucine, leucine, valine, 3-hydroxybutyrate, lactate, alanine, 2-oxoglutarate, glutathione, creatine, glycine, tyrosine, phenylalanine, histidine and remarkable decreases of lysine, acetate, n-acetyl-CH3, n-acetyl cysteine, glutamine, glutamate, methionine, choline, taurine, glucose and formate. The down regulation of glucose and the accumulated lactate indicated enhanced aerobic glycolysis for energy requirements in melanoma cells. Decreased taurine acted to fight against reactive oxygen species, as evidenced by an active glutathione system in melanoma cells. Amino acid profiles altered different from any other cancer cells. Tumor-related amino acids identified by NMR might be helping advance the field of therapeutic intervention in melanoma. Keywords: melanocytes, melanoma, NMR, multivariate analysis, pathway DOI: 10.7176/JBAH/15-1-01 Publication date: January 30th 202
The Design of Scientific Research Project Management System in Universities
Researching and designing the university scientific research project management system based on network is conducive to tracking, guiding and managing product life-cycle of the whole research procedure management of projects. It also can provide information support for the managers to make scientific research management decisions and contribute to advancing the management level of scientific research and management. Fully understanding the procedure of scientific research management system, the paper researched problems which are important to project management and designed the basic structure of the scientific research management system according to the manager’s demands. Adopting Myeclipse, Tomcat, Mysql development tools, the function models such as information publishment, achievement exhibition, project management and academic communication can be constructed. Therefore the goal of all-dimensional management of progress, resources and results can be realized. It can not only facilitate project directors to do comprehensivize management of project, but also helpful for the management sector to get the advanced progress information of all the internal scientific research projects. The management system can meet the need of academic institutions macro-management and decision demand of scientific activities, providing support for the project participators’ evaluation
Analytical Modelling of Formation Damage in One-phase and Two-phase Flows: Applications for Laboratory Experiments
I hereby present a Ph.D. thesis by publication. This thesis includes six journal publications, four of which have been published and two have been submitted for publication. This thesis is focussed on the application of analytical modelling in laboratory experiments of formation damage in one-phase and two-phase flows in porous media. It targets formation damage with chemical reactions, fines migration, as well as onedimensional (1D) and two-dimensional (2D) two-phase flows accounting for capillary end effects. The thesis develops a novel system of fundamental equations for reactive flows with large deposition of solid reaction products. A new class of exact analytical solutions has been derived for reactive flows with any arbitrary stoichiometric coefficients. The analytical solution yields breakthrough concentration and pressure drop type curves, significantly facilitating the interpretation of the laboratory data. The developed system of governing equations has been validated by laboratory modelling and can be used for the prediction of mineral precipitation chemical reactive flows in porous media. In addition, the three-point pressure method for large scale deposits has been investigated for the first time and the results show that the inclusion of outlet concentration data significantly decreases parameter uncertainty. The large parameter uncertainties without using outlet concentration arise due to the inability for the model to distinguish between a set of deposit profiles. Laboratory studies applying the three-point pressure method have also been conducted for fines migration in porous media to predict formation damage in a hydraulically fractured well. The results show that while pressure measurements alone can predict formation damage due to fracture fluid leak-off, breakthrough fines concentration is able to fully predict model functions and coefficients to characterise the system. The two-phase flow in porous media investigated in this thesis comprises steady-state and transient 1D flow with capillary end effects, and steady-state 2D flow with capillary end effects near a hydraulically fractured production well. Steady-state analytical solutions, along with transient numerical solutions, have been applied in the so-called steady-state-transient test (SSTT). It includes a three-dimensional (3D) modelling of the SSTT with the treatment of the simulated data by a 1D inverse solver. The main result shows a significant reduction in the 3D flow effects when using an inlet distributor with spiral (or concentric-circle) grooves rather than one with halfmoon grooves. Following this result, two SSTTs were carried out in the laboratory. In the concentriccircle SSTT, a weighting method for water cut measurements at the effluent was used, while in the half-moon SSTT, a visualisation method was used. Based on the results, the use of a concentric-circle distributor and the weighting method in SSTTs is recommended. Lastly, the exact solution to the steady-state 2D flow towards a fractured well was derived and applied to predict formation damage due to capillary-trapped water, known as water blocking. The results show water blocking is likely to be a significant factor in the productivity decline for the case study conducted.Thesis (Ph.D.) -- University of Adelaide, Australian School of Petroleum and Energy Resources, 202
4-Bromo-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-(4-nitrobenzylideneamino)-1H-pyrazole-3-carbonitrile
The title compound, C18H7BrCl2F3N5O2, is an L-shaped tricyclic imine. The pyrazole ring is essentially coplanar with the nitro-substituted benzene ring [dihedral angle = 3.6 (2)°] and approximately perpendicular to the trifluoromethylsubstituted ring [dihedral angle = 88.5 (2)°]
A Review of Current Studies on Internet Finance in China
The Internet and finance are accelerating into integration in the 21st Century. Internet Finance was firstly proposed by Ma Weihua, the former president of China Merchants Bank in July 2012. On the basis of 74 latest research literatures selected from CSSCI Journals, Chinese Core Journals, authoritative magazines and related newspapers, this paper summarizes the current domestic research progress and trend about Internet Finance according to three dimensions, such as the sources of journals, research subjects and research contents. This research shows that the current domestic researches are not only shallow and superficial, but also lack the theoretical analyses and model applications; and the wealth-based and bank-based Internet Finance will be the research focus in the future
4-Bromo-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-(4-methoxybenzylideneamino)-1H-pyrazole-3-carbonitrile
The title compound, C19H10BrCl2F3N4O, is an imine with an overall Y shape. The dihedral angles between the pyrazole ring and the methoxy- and trifluoromethyl-substituted benzene ring planes are 88.4 (2) and 65.8 (2)°, respectively
A Semantic Search Engine Based on SKOS Model Ontology in Agriculture
Abstract. A simple agriculture ontology system was constructed under extended SKOS model in this paper. A theme relevance algorithm based on terms' distances in ontology system was tested and applied in improving the Pagerank evaluating. And also an online agricultural semantic search engine named as Sonong was implemented and deployed for service on internet. This online engine provides semantic hierarchy inference with the ontology system and a satisfying ranking list of retrieved information
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