An Overview of Three Promising Mechanical, Optical, and Biochemical Engineering Approaches to Improve Selective Photothermolysis of Refractory Port Wine Stains

During the last three decades, several laser systems, ancillary technologies, and treatment modalities have been developed for the treatment of port wine stains (PWSs). However, approximately half of the PWS patient population responds suboptimally to laser treatment. Consequently, novel treatment modalities and therapeutic techniques/strategies are required to improve PWS treatment efficacy. This overview therefore focuses on three distinct experimental approaches for the optimization of PWS laser treatment. The approaches are addressed from the perspective of mechanical engineering (the use of local hypobaric pressure to induce vasodilation in the laser-irradiated dermal microcirculation), optical engineering (laser-speckle imaging of post-treatment flow in laser-treated PWS skin), and biochemical engineering (light- and heat-activatable liposomal drug delivery systems to enhance the extent of post-irradiation vascular occlusion)

Translating Western learning into practice: biofeedback therapy for bowel dysfunctional patients

Poster Presentations: SPP-P Modernisation of Healthcare: no. SPP-P7.26Conference Theme: Consolidating HealthcAre - 固本培員, 健行不

A nurse-led psycho-education programme for chinese carers of patients with colorectal cancer

<p>Association between the sexual behaviours and demographic and socio-economic characteristics.</p

Four-year prospective review of Colorectal Cancer Detection Rate at 'One-stop Rectal Bleeding Clinic' in Queen Mary Hospital

Session: SPP-P6 – Clinical Safety and Quality Service 2Poster Presentatio

The impact of indocyanine-green fluorescence imaging on left-sided colonic resection: A prospective study

Digital Poster, Lower GI 'Neoplasia 3': Poster no. DP-0510 / Paper no. 2045Perfusion is one of the most important factors in colonic anastomotic healing. The near-infrared light (NIR) technology and intravenous injection of fluorescent dye with indocyanine-green (ICG) allow intraoperative assessment of colonic microvascular perfusion. Aim: The objective is to assess the impact of using NIR+ICG in left-sided colonic resections. Method: A prospective study was carried out for patients who had colonic or rectal resections that involve ligation of the inferior mesenteric artery. The primary endpoint was whether there was a change in operative decision: transection site, decision for splenic flexure mobilization and decision for stoma. The secondary endpoint was the anastomotic leakage rate. Results: Thirty patients were recruited. The mean age was 64.5 ± 11.7 years. Approximately 66.7% were male and 33.3% were female. They had either cancer of the descending colon (3.3%), sigmoid colon (26.7%) or rectum (70.0%). Total mesorectal excision was performed in 63.3% of the cases. For the site of transection, there was a change in decision in 53.3% of the cases, in which 50.0% had a more proximal transection, and 3.3% had a more distal transection. When there was a change of transection site, the mean distance between the intended and eventual transection site was 3.90 ± 3.34 cm (range 1-12 cm). In 10.0% of the cases, there was a change in the decision on whether to mobilize the splenic flexure of the colon or not. Defunctioning stoma was performed in 70.0% of the cases. There was no change in the decision in terms of stoma fashioning. There was no clinical anastomotic leak observed. Conclusion: The use of NIR+ICG to assess bowel perfusion in left-sided colonic resection has a major impact on intraoperative decision. There is a role for further studies to evaluate whether it has a positive impact on reducing anastomotic leakage rate