1,979 research outputs found
Radar backscattering data for surfaces of geological interest
Radar backscattering data for surfaces of geological interes
The Mutual Interpretation of Active and Passive Microwave Sensor Outputs
Mutual interpretation of active and passive microwave sensor output
Spin transition in GdN@C, detected by low-temperature on-chip SQUID technique
We present a magnetic study of the GdN@C molecule, consisting of a
Gd-trimer via a Nitrogen atom, encapsulated in a C cage. This molecular
system can be an efficient contrast agent for Magnetic Resonance Imaging (MRI)
applications. We used a low-temperature technique able to detect small magnetic
signals by placing the sample in the vicinity of an on-chip SQUID. The
technique implemented at NHMFL has the particularity to operate in high
magnetic fields of up to 7 T. The GdN@C shows a paramagnetic
behavior and we find a spin transition of the GdN structure at 1.2 K. We
perform quantum mechanical simulations, which indicate that one of the Gd ions
changes from a state () to a state (), likely due to a charge transfer between the C cage and the ion
Investigating the Magnetospheres of Rapidly Rotating B-type Stars
Recent spectropolarimetric surveys of bright, hot stars have found that ~10%
of OB-type stars contain strong (mostly dipolar) surface magnetic fields (~kG).
The prominent paradigm describing the interaction between the stellar winds and
the surface magnetic field is the magnetically confined wind shock (MCWS)
model. In this model, the stellar wind plasma is forced to move along the
closed field loops of the magnetic field, colliding at the magnetic equator,
and creating a shock. As the shocked material cools radiatively it will emit
X-rays. Therefore, X-ray spectroscopy is a key tool in detecting and
characterizing the hot wind material confined by the magnetic fields of these
stars. Some B-type stars are found to have very short rotational periods. The
effects of the rapid rotation on the X-ray production within the magnetosphere
have yet to be explored in detail. The added centrifugal force due to rapid
rotation is predicted to cause faster wind outflows along the field lines,
leading to higher shock temperatures and harder X-rays. However, this is not
observed in all rapidly rotating magnetic B-type stars. In order to address
this from a theoretical point of view, we use the X-ray Analytical Dynamical
Magnetosphere (XADM) model, originally developed for slow rotators, with an
implementation of new rapid rotational physics. Using X-ray spectroscopy from
ESA's XMM-Newton space telescope, we observed 5 rapidly rotating B-type stars
to add to the previous list of observations. Comparing the observed X-ray
luminosity and hardness ratio to that predicted by the XADM allows us to
determine the role the added centrifugal force plays in the magnetospheric
X-ray emission of these stars.Comment: IAUS Conference Proceeding
Comparison of Narcotic Prescribing Habits Between Trainee and Attending Orthopaedic Surgeons
Background: Orthopaedic surgeons are among the highest prescribing physicians of narcotics to opioidnaïve patients. Despite the current opioid epidemic, few studies have specifically quantified the appropriate amount of opioids necessary for postoperative pain control. We hypothesized a significant variability in the quantity of postoperative opioids prescribed among trainee (ie, residents and fellows) and attending surgeons at a single institution.
Methods: Postoperative narcotic prescribing habits were assessed using an anonymous survey. Ultimately, 28 trainee physicians and 17 attending physicians responded to the survey (86.5%). The survey recorded the amount of 5-mg oxycodone tablets that were commonly prescribed to manage pain after various typical orthopaedic procedures (eg, total knee arthroplasty). Non-narcotic analgesic use was also measured. Mean, standard deviation, and variance values were calculated, with significance set at α = 0.05.
Results: After the following procedures, the respondents reported prescribing the following quantities of 5-mg oxycodone tablets: total knee arthroplasty, 56 (SD, 16); total hip arthroplasty, 53 (SD, 13); anterior cruciate ligament reconstruction, 38 (SD, 16); partial meniscectomy, 23 (SD, 14); arthroscopic rotator cuff repair, 39 (SD, 16); carpal tunnel release, 10 (SD, 10); A1 pulley release for treating trigger finger, 9 (SD, 9); open reduction and internal fixation (ORIF) for treating distal radius fractures, 32 (SD, 16); and ORIF for treating ankle fractures, 39 (SD, 15). Statistically significant variation existed between trainee and attending physicians for total hip arthroplasty and A1 pulley release. There was no difference for acetaminophen or nonsteroidal anti-inflammatory drugs, with about 70% of patients receiving at least one of these adjuncts.
Conclusions: Variability exists in postoperative opioid prescribing habits between trainee and attending physicians at the academic training institution we accessed. In light of the ongoing opioid epidemic, institutions may benefit from standardized postoperative pain protocols
Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics
There is growing interest in using embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) derivatives for tissue regeneration. However, an increased understanding of human immune responses to stem cell-derived allografts is necessary for maintaining long-term graft persistence. To model this alloimmunity, humanized mice engrafted with human hematopoietic and immune cells could prove to be useful. In this study, an in-depth analysis of graft-infiltrating human lymphocytes and splenocytes revealed that humanized mice incompletely model human immune responses toward allogeneic stem cells and their derivatives. Furthermore, using an allogenized mouse model, we show the feasibility of reconstituting immunodeficient mice with a functional mouse immune system and describe a key role of innate immune cells in the rejection of mouse stem cell allografts
Geriatric Hip Fracture Quality Initiative
Introduction:
Multiple studies demonstrate increased morbidity, mortality, and loss of independence after hip fractures in geriatric patients. The 1-year mortality rate after a hip fracture has been estimated at anywhere from 14% to 58%. Hip fractures are one of the most common injuries evaluated by the UNM Orthopedic department. Geriatric hip fracture protocols have shown improved outcomes at many other centers with regard to improved functionality and decreased morbidity. The goal of this initiative is to improve outcomes with regard to length of hospital stay, functionality after surgery, and as a result, decreased morbidity and mortality.
Materials/methods:
All deaths in the orthopedic department were reviewed and analyzed from June 2009 to July 2019. Deaths were identified from morbidity and mortality submissions and NSQIP data. The geriatric hip fracture protocol was developed and implemented in Fall 2019, with non-critical care patients being primarily admitted to orthopedics, with hospitalist co-management. Specific post-operative and pain order sets were developed for efficiency and improved standard of care.
Results:
Early results of the newly developed geriatric hip fracture protocol demonstrate decreased length of stay in the hospital and earlier time to surgical intervention. It is too early to determine if morbidity and mortality has seen any decrease, however this can be anticipated with earlier time to surgery and decreased time in the hospital.
Conclusions:
We identified a need and successfully developed an initiative to improve care for geriatric patients with hip fractures. Implementation of this protocol decreased length of hospital stay as well as time to surgery. The analysis of the effect of this protocol on overall morbidity and mortality is ongoing
Research in and application of modern automatic control theory to nuclear rocket dynamics and control, volume I Semiannual status report
Linear optimal feedback control theory for nuclear rocket dynamics and control problem
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